Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e>  <link rel=3DPresentation-XML href=3D"OptymalnyprofilchoregozHRCP_pliki/pres= .xml"> <meta name=3DDescription content=3D"2009-10-08: Optymalny profil chorego z HRPC do leczenia chemiote= rapią"> <meta http-equiv=3Dexpires content=3D0> <![if !ppt]><script>  </script> <![endif]> </head> <body> <script></script><font face=3DArial size=3D2><b> <p>Ta prezentacja zawiera zawartość, którą przeglądarka może nie wyświetlać prawidłowo.</p> <p>Jeśli mimo wszystko chcesz kontynuować, kliknij <a href=3D"OptymalnyprofilchoregozHRCP_pliki/frame.htm">tutaj</a>.</p> </b></font><script></script> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/master03.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" 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1;position:absolute;top:74.25%;left:15.91%;width:68.16%;height:6.25%'><span style=3D'font-size:84%;color:#898989'>Katowice</span></div> </div> <div v:shape=3D"_x0000_s2052"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'text-align:center;mso-char-wrap:1;mso-kinsoku-over= flow: 1;position:absolute;top:94.0%;left:35.2%;width:29.77%;height:3.0%'><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:67%;color:#898989'>Pozna</span><span style=3D'mso-ascii-= font-family: Calibri;mso-hansi-font-family:Calibri;font-size:67%;color:#898989'>ń<= /span><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:67%;color:#898989'> 19 czerwca 2009</span></div> </div> </p:slide></div> </body> 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top:65.51%;left:3.66%;width:82.75%;height:34.48%'>m-cy </span></div> <div id=3D"_x0000_s5123_280_389" style=3D'mso-char-wrap:1;mso-kinsoku-over= flow: 1;position:absolute;top:91.25%;left:5.99%;width:91.76%;height:3.0%;white-s= pace: nowrap'><span style=3D'mso-special-format:nobullet;display:none;font-famil= y: Arial'>•</span><span style=3D'font-size:38%'>Petrylak DP. Chemothera= py for the treatment .. w Prostate and renal cancer…. Parthenon Publishing Group 2002 </span></div> <div style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1;position:absolute; top:95.25%;left:5.99%;width:88.2%;height:7.5%'><span style=3D'position:abs= olute; top:0%;left:4.24%;width:95.75%;height:100.0%'><span style=3D'visibility:hi= dden'><span style=3D'mso-special-format:bullet;position:absolute;left:-4.43%;font-fami= ly: Arial'>•</span></span><span style=3D'mso-special-format:lastCR;displ= ay: none'> </span></span></div> </div> </p:slide></div> <p:animation number=3D"-1740910880"/><oa:par id=3D"TimeNode0" dur=3D"indefi= nite" restart=3D"never" p:nodeType=3D"timingRoot"> <oa:seq id=3D"TimeNode1" dur=3D"indefinite" prev=3D"document.onpptprev" next=3D"document.onpptnext" concurrent=3D"enabled" nextAction=3D"seek" p:nodeType=3D"mainSeq"> <oa:par id=3D"TimeNode2" begin=3D"indefinite" fill=3D"hold"> <oa:par id=3D"TimeNode3" begin=3D"0.0" fill=3D"hold"> <oa:par id=3D"TimeNode4" o:presetID=3D"ppt_22" o:presetClass=3D"entranc= e" 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style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s6146" type=3D"= #_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s6147" type=3D"= #_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s6146" class=3DT style=3D'mso-char-wrap:1;mso-kinso= ku-overflow: 1;position:absolute;top:7.25%;left:5.99%;width:88.2%;height:10.25%'>HRCP</= div> <div v:shape=3D"_x0000_s6147" class=3DB> <div style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1'><span style=3D'posit= ion: absolute;top:24.0%;left:5.99%;width:104.86%;height:7.5%'><span style=3D'mso-special-format:nobullet;display:none;font-family:Arial'>̶= 6;</span><span style=3D'mso-spacerun:yes'> </span>Progresja choroby w t= rakcie hormonoterapii u </span><span style=3D'position:absolute;top:31.0%;left:9.= 73%; width:99.25%;height:7.5%'>pacjenta z udokumentowanym rozpoznaniem </span><= span style=3D'position:absolute;top:38.0%;left:9.73%;width:101.31%;height:7.5%'= >raka gruczołu krokowego<span style=3D'mso-spacerun:yes'> </span>po wykorzystaniu co </span><span style=3D'position:absolute;top:45.25%;left:9= .73%; width:84.45%;height:7.5%'>najmniej II rzutów leczenia </span></= div> <div style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1'><span style=3D'posit= ion: absolute;top:53.75%;left:9.73%;width:95.69%;height:7.5%'><span style=3D'mso-special-format:bullet;position:absolute;left:-3.91%;font-fami= ly: Arial'>•</span>I rzut –blokada analogiem GNRH (tzw. pełna= </span><span style=3D'position:absolute;top:60.75%;left:9.73%;width:91.01%;height:7.5%'= >blokada nie daje zysku klinicznego, a tylko </span><span style=3D'position:absolut= e; top:68.0%;left:9.73%;width:84.45%;height:7.5%'>większą ilość działań ubocznych) </span></div> <div style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1'><span style=3D'posit= ion: absolute;top:76.5%;left:9.73%;width:85.95%;height:7.5%'><span style=3D'mso-special-format:bullet;position:absolute;left:-4.35%;font-fami= ly: Arial'>•</span>II rzut – antyandrogeny (steroidowe lub </span>= <span style=3D'position:absolute;top:83.5%;left:9.73%;width:84.45%;height:7.5%'>= niesteroidowe)</span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0054.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 54.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: HRCP"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"7"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s7170" type=3D"= #_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s7171" type=3D"= #_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s7170" class=3DT style=3D'position:absolute;top:7.2= 5%; left:5.99%;width:88.2%;height:10.25%'>HRCP</div> <div v:shape=3D"_x0000_s7171" class=3DB> <div style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1;position:absolute; top:24.0%;left:5.99%;width:88.2%;height:7.5%'><span style=3D'mso-special-f= ormat: nobullet;display:none;font-family:Arial'>•</span>Wskazania do rozpoczęcia terapii: </div> <div style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1;position:absolute; top:32.5%;left:5.99%;width:88.2%;height:7.5%'><span style=3D'position:abso= lute; top:0%;left:4.24%;width:95.75%;height:100.0%'><span style=3D'mso-special-f= ormat: bullet;position:absolute;left:-4.43%;font-family:Arial'>•</span>Prog= resja kliniczna </span></div> <div style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1;position:absolute; top:41.0%;left:5.99%;width:88.2%;height:7.5%'><span style=3D'position:abso= lute; top:0%;left:4.24%;width:95.75%;height:100.0%'><span style=3D'mso-special-f= ormat: bullet;position:absolute;left:-4.43%;font-family:Arial'>•</span>Nara= stanie poziomu PSA </span></div> <div style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1;position:absolute; top:49.5%;left:5.99%;width:88.2%;height:7.5%'><span style=3D'position:abso= lute; top:0%;left:4.24%;width:95.75%;height:100.0%'><span style=3D'mso-special-f= ormat: bullet;position:absolute;left:-4.43%;font-family:Arial'>•</span>Kast= racyjny poziom testosteronu </span></div> <div style=3D'position:absolute;top:58.0%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span><span style=3D'mso-special-format:lastCR;display:none'> </span></span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0055.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 55.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Progresja w trakcie leczeni= a HRCP"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"8"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s8194" type=3D"= #_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s8195" type=3D"= #_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s8194" class=3DT style=3D'position:absolute;top:7.2= 5%; left:-.37%;width:100.74%;height:10.25%'>Progresja w trakcie leczenia HRCP<= /div> <div v:shape=3D"_x0000_s8195" class=3DB><span style=3D'position:absolute;t= op:24.0%; left:9.73%;width:94.94%;height:7.5%'><span class=3DBB style=3D'position:ab= solute; left:-3.94%'>•</span>Obecnie brak standardów postępowani= a po </span><span style=3D'position:absolute;top:31.0%;left:9.73%;width:84.45%; height:7.5%'>progresji<span style=3D'mso-spacerun:yes'> </span>po CH= T w HRPC </span><span style=3D'position:absolute;top:39.5%;left:9.73%; width:84.45%;height:7.5%'><span class=3DBB style=3D'position:absolute;left= :-4.43%'>•</span>Możliwość ponownego zastosowania </span><span style=3D'position:absolute;top:46.5%; left:9.73%;width:84.45%;height:7.5%'>hormonoterapii </span> <div style=3D'position:absolute;top:55.25%;left:5.99%;width:88.2%;height:7= .5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Powt&oacu= te;rna CHT</span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0049.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 49.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: HRCP"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"9"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s9218" type=3D"= #_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s9219" type=3D"= #_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s9218" class=3DT style=3D'position:absolute;top:7.2= 5%; left:5.99%;width:88.2%;height:10.25%'>HRCP</div> <div v:shape=3D"_x0000_s9219" class=3DB><span style=3D'position:absolute;t= op:24.0%; left:9.73%;width:84.45%;height:7.5%'><span class=3DBB style=3D'position:ab= solute; left:-4.43%'>•</span>Pacjent z HRPC typowo jest pacjentem </span><sp= an style=3D'position:absolute;top:31.0%;left:9.73%;width:84.45%;height:7.5%'>= starszym, często z licznymi chorobami </span><span style=3D'position:absolute; top:38.0%;left:9.73%;width:84.45%;height:7.5%'>współistniej= 61;cymi. </span><span style=3D'position:absolute;top:46.5%;left:9.73%;width:96.81%;height:7.5%'>= <span class=3DBB style=3D'position:absolute;left:-3.86%'>•</span>Odpowiedzi terapeutyczne (RR) na klasyczną </span><span style=3D'position:absolu= te; top:53.75%;left:9.73%;width:100.56%;height:7.5%'>chemioterapię jedn&#= 261; substancją<span style=3D'mso-spacerun:yes'> </span>w serii bada= ń </span><span style=3D'position:absolute;top:60.75%;left:9.73%;width:95.31%; height:7.5%'>wynosiły 8,7%, a mediana przeżycia 9-12 m-</span><s= pan style=3D'position:absolute;top:68.0%;left:9.73%;width:84.45%;height:7.5%'>= cy* </span> <div style=3D'position:absolute;top:76.5%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span> </span></div> <div style=3D'position:absolute;top:85.0%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span> </span></div> <div style=3D'position:absolute;top:92.75%;left:5.99%;width:88.2%;height:2= .75%'><span style=3D'mso-special-format:nobullet;display:none;font-family:Arial'>̶= 6;</span><span style=3D'font-size:34%'>Yagoda A, Petrylak D Cancer 1993;71:1098-109</span= ></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0023.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type 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style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s10242" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"t"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s10243" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s10243" class=3DB> <div style=3D'text-align:center;position:absolute;top:24.0%;left:5.99%; width:88.2%;height:7.5%'><span style=3D'mso-special-format:nobullet;displa= y: none;font-family:Arial'>•</span> </div> <div style=3D'text-align:center;position:absolute;top:32.5%;left:5.99%; width:88.2%;height:7.5%'><span style=3D'mso-special-format:nobullet;displa= y: none;font-family:Arial'>•</span> </div> <div style=3D'text-align:center;position:absolute;top:41.5%;left:5.99%; width:88.2%;height:10.25%'><span style=3D'mso-special-format:nobullet; display:none;font-family:Arial'>•</span><span style=3D'font-size:138= %'>Doświadczenia własne</span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0020.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 20.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D2009-10-08> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"11"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s11266" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"t"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s11267" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s11267" class=3DB><span style=3D'position:absolute; top:24.0%;left:5.99%;width:97.94%;height:7.5%'><span style=3D'mso-special-= format: nobullet;display:none;font-family:Arial'>•</span><span style=3D'mso-spacerun:yes'> </span>Do Ośrodka skier= owano łącznie 23 chorych </span><span style=3D'position:absolute;top:3= 1.0%; left:9.73%;width:84.45%;height:7.5%'>spełniających kryteria HRPC </span><span style=3D'position:absolute;top:39.5%;left:5.99%; width:88.2%;height:7.5%'><span style=3D'mso-special-format:nobullet;displa= y: none;font-family:Arial'>•</span>Do leczenia<span style=3D'mso-spacerun:yes'> </span>chemioterapią<span style=3D'mso-spacerun:yes'> </span>I rzutu </span><span style=3D'pos= ition: absolute;top:46.5%;left:9.73%;width:84.45%;height:7.5%'>zakwalifikowano:&#= 13;</span> <div style=3D'position:absolute;top:55.25%;left:5.99%;width:88.2%;height:7= .5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>21 choryc= h </span></div> <div style=3D'position:absolute;top:63.75%;left:5.99%;width:88.2%;height:7= .5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Wiek 49 d= o 81 lat </span></div> <span style=3D'position:absolute;top:72.25%;left:9.73%;width:85.39%;height= :7.5%'><span class=3DBB style=3D'position:absolute;left:-4.38%'>•</span>Podana ilość cykli 2 do 10 (średnio 5,6), </span><span style=3D'position:absolute;top:79.25%;left:9.73%;width:84.45%;height:7.5%'= >łącznie 117 podań </span> <div style=3D'position:absolute;top:87.75%;left:5.99%;width:88.2%;height:7= .5%'><span style=3D'mso-special-format:nobullet;display:none;font-family:Arial'>̶= 6;</span><span style=3D'mso-special-format:lastCR;display:none'> </span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0025.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type 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style=3D'position:absolute; top:2.5%;left:5.99%;width:88.2%;height:10.25%'>Choroby współistniejące<br> </span><span style=3D'position:absolute;top:12.25%;left:5.99%;width:88.2%; height:10.25%'>istotne klinicznie</span></div> <div v:shape=3D"_x0000_s12292"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1;position:ab= solute; top:24.0%;left:5.99%;width:83.52%;height:8.25%'><span style=3D'font-family= :Calibri; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;font-size:200%; color:white'><b>Nadci</b></span><span style=3D'mso-ascii-font-family:Calib= ri; mso-hansi-font-family:Calibri;font-size:200%;color:white'><b>ś</b></s= pan><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:white'><b>nienie<span style=3D'mso-spacerun:yes'> </span>t</b></span><span style=3D'mso-as= cii-font-family: Calibri;mso-hansi-font-family:Calibri;font-size:200%;color:white'><b>ę= ;</b></span><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:white'><b>tnicze WHO<span style=3D'mso-spacerun:yes'> </span>I-III)</b></span><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:white;mso-special-format:lastCR;display:none'= ><b> </b></span></div> </div> <div v:shape=3D"_x0000_s12293"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'text-align:center;mso-char-wrap:1;mso-kinsoku-over= flow: 1;position:absolute;top:24.0%;left:81.46%;width:12.73%;height:8.25%'><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:white'><b>17</b></span><span style=3D'font-fa= mily: Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri; font-size:200%;color:white;mso-special-format:lastCR;display:none'><b> = ;</b></span></div> </div> <div v:shape=3D"_x0000_s12294"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1;position:ab= solute; top:33.25%;left:5.99%;width:73.59%;height:8.25%'><span style=3D'font-famil= y: Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri; font-size:200%;color:black'>Choroba wie</span><span style=3D'mso-ascii-fon= t-family: Calibri;mso-hansi-font-family:Calibri;font-size:200%;color:black'>ń</= span><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:black'>cowa </span><span style=3D'font-family= :Calibri; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;font-size:200%; color:black;mso-special-format:lastCR;display:none'> </span></div> </div> <div v:shape=3D"_x0000_s12295"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'text-align:center;mso-char-wrap:1;mso-kinsoku-over= flow: 1;position:absolute;top:33.25%;left:81.46%;width:12.73%;height:8.25%'><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:black'>11</span><span style=3D'font-family:Ca= libri; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;font-size:200%; color:black;mso-special-format:lastCR;display:none'> </span></div> </div> <div v:shape=3D"_x0000_s12296"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1;position:ab= solute; top:42.5%;left:5.99%;width:87.26%;height:8.25%'><span style=3D'font-family= :Calibri; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;font-size:200%; color:black'>Niewydolno</span><span style=3D'mso-ascii-font-family:Calibri; mso-hansi-font-family:Calibri;font-size:200%;color:black'>ść</sp= an><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:black'> kr</span><span style=3D'mso-ascii-fon= t-family: Calibri;mso-hansi-font-family:Calibri;font-size:200%;color:black'>ą&#= 380;</span><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:black'>enia (NYHA I i II)</span><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:black;mso-special-format:lastCR;display:none'= > </span></div> </div> <div v:shape=3D"_x0000_s12297"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'text-align:center;mso-char-wrap:1;mso-kinsoku-over= flow: 1;position:absolute;top:42.5%;left:81.46%;width:12.73%;height:8.25%'><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:black'>7</span><span style=3D'font-family:Cal= ibri; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;font-size:200%; color:black;mso-special-format:lastCR;display:none'> </span></div> </div> <div v:shape=3D"_x0000_s12298"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1;position:ab= solute; top:52.0%;left:5.99%;width:73.59%;height:8.25%'><span style=3D'font-family= :Calibri; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;font-size:200%; color:black'>Cukrzyca typ II</span><span style=3D'font-family:Calibri; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;font-size:200%; color:black;mso-special-format:lastCR;display:none'> </span></div> </div> <div v:shape=3D"_x0000_s12299"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'text-align:center;mso-char-wrap:1;mso-kinsoku-over= flow: 1;position:absolute;top:52.0%;left:81.46%;width:12.73%;height:8.25%'><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:black'>5</span><span style=3D'font-family:Cal= ibri; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;font-size:200%; color:black;mso-special-format:lastCR;display:none'> </span></div> </div> <div v:shape=3D"_x0000_s12300"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1;position:ab= solute; top:61.25%;left:5.99%;width:73.59%;height:8.25%'><span style=3D'font-famil= y: Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri; font-size:200%;color:black'>Inne</span><span style=3D'font-family:Calibri; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;font-size:200%; color:black;mso-special-format:lastCR;display:none'> </span></div> </div> <div v:shape=3D"_x0000_s12301"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'text-align:center;mso-char-wrap:1;mso-kinsoku-over= flow: 1;position:absolute;top:61.25%;left:81.46%;width:12.73%;height:8.25%'><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:black'>2</span><span style=3D'font-family:Cal= ibri; 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font-size:222%;color:black'>CR</span><span style=3D'font-family:Calibri; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;font-size:222%; color:black;mso-special-format:lastCR;display:none'> </span></div> </div> <div v:shape=3D"_x0000_s14344"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'text-align:center;mso-char-wrap:1;mso-kinsoku-over= flow: 1;position:absolute;top:40.25%;left:75.28%;width:13.85%;height:9.25%'><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:222%;color:black'>1</span><span style=3D'font-family:Cal= ibri; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;font-size:222%; color:black;mso-special-format:lastCR;display:none'> </span></div> </div> <div v:shape=3D"_x0000_s14345"> <div 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xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 38.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D2009-10-08> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" 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width:88.2%;height:10.25%'><span style=3D'mso-special-format:nobullet; display:none;font-family:Arial'>•</span><span style=3D'font-size:138= %; display:none'> </span></div> <div style=3D'text-align:center;position:absolute;top:35.5%;left:5.99%; width:88.2%;height:10.25%'><span style=3D'mso-special-format:nobullet; display:none;font-family:Arial'>•</span><span style=3D'font-size:138= %'>Prezentacja przypadków</span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0040.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 40.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Wywiad"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"16"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s16386" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s16387" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s16386" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Wywiad</div> <div v:shape=3D"_x0000_s16387" class=3DB> <div style=3D'position:absolute;top:24.0%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Rozpoznan= ie ustalono w wieku 67 lat </span></div> <span style=3D'position:absolute;top:32.5%;left:9.73%;width:100.93%;height= :7.5%'><span class=3DBB style=3D'position:absolute;left:-3.71%'>•</span>PSA 27 ng= /ml, bez cech rozsiewu<span style=3D'mso-spacerun:yes'> </span>w badaniach </= span><span style=3D'position:absolute;top:39.5%;left:9.73%;width:84.45%;height:7.5%'>= obrazowych. </span><span style=3D'position:absolute;top:48.0%;left:5.99%;width:88.2%;height:7.5%'><= span style=3D'mso-special-format:nobullet;display:none;font-family:Arial'>̶= 6;</span><span style=3D'mso-spacerun:yes'> </span>Operowany z założeniem leczenia </span><span style=3D'position:absolute; top:55.25%;left:9.73%;width:84.45%;height:7.5%'>radykalnego </span><sp= an style=3D'position:absolute;top:63.75%;left:9.73%;width:95.88%;height:7.5%'= ><span class=3DBB style=3D'position:absolute;left:-3.9%'>•</span>Histologic= znie stopień złośliwości Gleason 8, </span><span style=3D'position:absolute;top:70.75%;left:9.73%;width:84.45%;height:7.5%'= >naciekanie torebki stercza </span> <div style=3D'position:absolute;top:79.25%;left:5.99%;width:97.37%;height:= 7.5%'><span style=3D'position:absolute;top:0%;left:3.84%;width:96.15%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.0%'>•</span>Po operacj= i spadek wartości PSA do 2ng/ml</span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0041.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 41.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Wywiad c.d."> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"17"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s17410" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s17411" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s17410" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Wywiad c.d.</div> <div v:shape=3D"_x0000_s17411" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:84.45%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>W 6 miesięcy po operacji – narastanie </span><span style=3D'position:absolute;top:31= .0%; left:9.73%;width:100.0%;height:7.5%'>poziomu PSA, w CT stwierdzono powiększenie </span><span style=3D'position:absolute;top:38.0%;left:9= .73%; width:84.83%;height:7.5%'>węzłów chłonnych miednicy małej oraz </span><span style=3D'position:absolute;top:45.25%;left:9.= 73%; width:84.45%;height:7.5%'>ogniska osteosklerotyczne w kościach </span= ><span style=3D'position:absolute;top:52.25%;left:9.73%;width:94.19%;height:7.5%'= >miednicy, klinicznie obrzęk kończyny dolnej </span><span style=3D'position= :absolute; top:59.5%;left:9.73%;width:84.45%;height:7.5%'>(ucisk na naczynia)</span><= /div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0026.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 26.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Leczenie"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"18"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s18434" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s18435" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s18434" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Leczenie</div> <div v:shape=3D"_x0000_s18435" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:98.5%;height:7.5%'><span class=3DBB style=3D'po= sition: absolute;left:-3.8%'>•</span>Włączono pełną blokadę hormonalną (analog </span><span style=3D'position:absolu= te; top:31.0%;left:9.73%;width:84.45%;height:7.5%'>GN-RH oraz flutamid, a następnie </span><span style=3D'position:absolute;top:38.0%;left:9.73= %; width:88.38%;height:7.5%'>bicalutamid), oraz w związku z objawami </s= pan><span style=3D'position:absolute;top:45.25%;left:9.73%;width:84.45%;height:7.5%'= >uciskowymi<span style=3D'mso-spacerun:yes'> </span>paliatywną RT </span><sp= an style=3D'position:absolute;top:53.75%;left:9.73%;width:97.37%;height:7.5%'= ><span class=3DBB style=3D'position:absolute;left:-3.84%'>•</span>Uzyskano ustąpienie dolegliwości klinicznych </span><span style=3D'positi= on: absolute;top:60.75%;left:9.73%;width:84.45%;height:7.5%'>oraz spadek pozio= mu PSA < 4ng/ml </span><span style=3D'position:absolute;top:69.25%; left:9.73%;width:84.45%;height:7.5%'><span class=3DBB style=3D'position:ab= solute; left:-4.43%'>•</span>Po 28 miesiącach leczenia bóle kost= ne, </span><span style=3D'position:absolute;top:76.5%;left:9.73%;width:84.45%;height:7.5%'>= narastanie<span style=3D'mso-spacerun:yes'> </span>poziomu PSA, zmiany </span><span style=3D'position:absolute;top:83.5%;left:9.73%;width:97.94%;height:7.5%'>= osteolityczno – osteosklerotyczne w kościach </span><span style=3D'position:a= bsolute; top:90.75%;left:9.73%;width:84.45%;height:7.5%'>miednicy i kręgosłupa. </span></div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0039.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 39.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Stwierdzenie HRPC"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"19"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s19458" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s19459" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s19458" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Stwierdzenie HRPC</div> <div v:shape=3D"_x0000_s19459"> <div class=3DB><span style=3D'position:absolute;top:24.0%;left:9.73%;width= :92.32%; height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.05%'>R= 26;</span>70 letni pracownik umysłowy, mieszkaniec </span><span style=3D'position:= absolute; top:31.0%;left:9.73%;width:84.45%;height:7.5%'>dużego miasta </s= pan></div> <div class=3DB style=3D'position:absolute;top:39.5%;left:5.99%;width:88.2%; height:7.5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.7= 5%; height:100.0%'><span class=3DBB style=3D'position:absolute;left:-4.43%'>&#= 8226;</span>Choroby współistniejące: </span></div> <div class=3DB1 style=3D'position:absolute;top:48.0%;left:11.04%;width:83.= 14%; height:6.5%'><span style=3D'position:absolute;top:0%;left:3.6%;width:96.17= %; height:100.0%'><span style=3D'mso-special-format:bullet;position:absolute; left:-3.74%;font-family:Wingdings'>Ø</span>Nadciśnienie tętnicze </span></div> <div class=3DB1 style=3D'position:absolute;top:55.5%;left:11.04%;width:83.= 14%; height:6.5%'><span style=3D'position:absolute;top:0%;left:3.6%;width:96.17= %; height:100.0%'><span style=3D'mso-special-format:bullet;position:absolute; left:-3.74%;font-family:Wingdings'>Ø</span>Choroba wieńcowa (leczony od 15 lat) </span></div> <div class=3DB style=3D'position:absolute;top:63.0%;left:5.99%;width:93.82= %; height:7.5%'><span style=3D'position:absolute;top:0%;left:3.99%;width:96.0= %; height:100.0%'><span class=3DBB style=3D'position:absolute;left:-4.15%'>&#= 8226;</span>Wieloletni palacz tytoniu, od 3 lat nie pali </span></div> <div class=3DB style=3D'position:absolute;top:71.5%;left:5.99%;width:88.2%; height:7.5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.7= 5%; height:100.0%'><span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span></span><span style=3D'mso-special-format:lastCR;display:none'> </span></span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0027.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 27.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Leczenie c.d."> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"20"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s20482" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s20483" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s20482" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Leczenie c.d.</div> <div v:shape=3D"_x0000_s20483" class=3DB> <div style=3D'position:absolute;top:24.0%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Przy przyjęciu: </span></div> <div style=3D'position:absolute;top:32.5%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Stan ogólny WHO I/II </span></div> <span style=3D'position:absolute;top:41.0%;left:9.73%;width:93.63%;height:= 7.5%'><span class=3DBB style=3D'position:absolute;left:-4.0%'>•</span>Nadciś= ;nienie wyrównane lekami, zapis EKG </span><span style=3D'position:absolute; top:48.0%;left:9.73%;width:84.45%;height:7.5%'>bez cech ostrego niedokrwienia </span><span style=3D'position:absolute;top:56.5%;left:9= .73%; width:93.82%;height:7.5%'><span class=3DBB style=3D'position:absolute;left= :-3.99%'>•</span>Układ krwiotwórczy, parametry wydolności </span><span style=3D'posit= ion: absolute;top:63.75%;left:9.73%;width:97.19%;height:7.5%'>wątroby oraz poziom kreatyniny prawidłowe </span><span style=3D'position:absol= ute; top:72.25%;left:9.73%;width:96.25%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-3.89%'>•</span>Poziom PSA narastający w ciągu 2 tyg<span style=3D'mso-spacerun:yes'> </span>z 79,8 </span><span style=3D'position:absolute;top:79.25%;left:9.73= %; width:84.45%;height:7.5%'>do 168ng/ml </span> <div style=3D'position:absolute;top:87.75%;left:5.99%;width:88.2%;height:7= .5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Poziom testosteronu - kastracyjny</span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0028.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 28.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Chemioterapia"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"21"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s21506" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s21507" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s21506" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Chemioterapia</div> <div v:shape=3D"_x0000_s21507" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:92.32%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.05%'>•</span>Docetaxel + Predniso= n w pełnych dawkach </span><span style=3D'position:absolute;top:31.0%; left:9.73%;width:84.45%;height:7.5%'>należnych </span><span style=3D'position:absolute;top:39.5%;left:9.73%;width:98.12%;height:7.5%'>= <span class=3DBB style=3D'position:absolute;left:-3.81%'>•</span>Po I cyklu znaczące zmniejszenie dolegliwości </span><span style=3D'positio= n: absolute;top:46.5%;left:9.73%;width:84.45%;height:7.5%'>bólowych (odstawiono <i>opioidy</i>) </span><span style=3D'position:absolute; top:55.25%;left:9.73%;width:84.45%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Łącznie IX cykli, bez opóźnień, bez </span><span style=3D'position:a= bsolute; top:62.25%;left:9.73%;width:88.38%;height:7.5%'>toksyczności >WHO = II, z dobra tolerancją </span><span style=3D'position:absolute;top:70= .75%; left:9.73%;width:91.01%;height:7.5%'><span class=3DBB style=3D'position:ab= solute; left:-4.11%'>•</span>Powolny spadek poziomu PSA do VI cyklu, </span>= <span style=3D'position:absolute;top:77.75%;left:9.73%;width:88.38%;height:7.5%'= >następnie stabilizacja, (bez<span style=3D'mso-spacerun:yes'> </span>normalizacji)<span style=3D'mso-spacerun:yes'> </span></span>= </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0029.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 29.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Follow-up"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"22"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s22530" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s22531" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s22530" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Follow-up</div> <div v:shape=3D"_x0000_s22531" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:93.25%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.01%'>•</span>Wobec braku dalszej regresji poziomu PSA, </span><span style=3D'position:absolute;top:31.0%; left:9.73%;width:100.18%;height:7.5%'>całkowitego ustąpienia dolegliwości bólowych </span><span style=3D'position:absolute; top:38.0%;left:9.73%;width:85.95%;height:7.5%'>oraz zmęczenia pacjenta chemioterapią </span><span style=3D'position:absolute;top:45.25%; left:9.73%;width:88.57%;height:7.5%'>odstąpiono od kontynuacji CHT i podjęto </span><span style=3D'position:absolute;top:52.25%;left:9.73%; width:98.12%;height:7.5%'>próbę leczenia hormonalnego (analog GN-RH </span><span style=3D'position:absolute;top:59.5%;left:9.73%;width:8= 4.45%; height:7.5%'>+ Bicalutamid) oraz bisfosfoniany. </span><span style=3D'position:absolute;top:68.0%;left:9.73%;width:100.56%;height:7.5%'= ><span class=3DBB style=3D'position:absolute;left:-3.72%'>•</span>Leczenie prowadzono przez 9 miesięcy; stabily </span><span style=3D'position:a= bsolute; top:75.0%;left:9.73%;width:88.57%;height:7.5%'>obraz kliniczny, poziom PSA= ok. 20 ng/ml</span></div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0030.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 30.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Follow-up"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"23"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s23554" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s23555" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s23554" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Follow-up</div> <div v:shape=3D"_x0000_s23555" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:84.45%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Po 9 miesiącach progresja: nasilenie </span><span style=3D'position:absolute;top:31.0%; left:9.73%;width:84.45%;height:7.5%'>dolegliwości bólowych, narastanie PSA </span><span style=3D'position:absolute;top:39.5%;left:= 9.73%; width:100.74%;height:7.5%'><span class=3DBB style=3D'position:absolute;lef= t:-3.71%'>•</span>Naciek w trzonach kręgów L4 i L5 – stabilizacja </span><span style=3D'position:absolute;top:46.5%;left:9.73%;width:84.45%;height:7.5%'>= operacyjna, a następnie paliatywna RT </span><span style=3D'position:absolute; top:55.25%;left:9.73%;width:97.56%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-3.83%'>•</span>Wobec narastania objawów chorobowych<span style=3D'mso-spacerun:yes'> </span>w= </span><span style=3D'position:absolute;top:62.25%;left:9.73%;width:93.82%;height:7.5%'= >tym dolegliwości bólowych zdecydowano o </span><span style=3D'posi= tion: absolute;top:69.25%;left:9.73%;width:84.45%;height:7.5%'>ponownym włączeniu leczenia </span><span style=3D'position:absolute;top:7= 6.5%; left:9.73%;width:84.45%;height:7.5%'>cytostatycznego </span> <div style=3D'position:absolute;top:85.0%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Poziom PSA 210ng/ml</span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0031.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 31.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: CHT – II rzut"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"24"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s24578" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s24579" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s24578" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>CHT – II rzut</div> <div v:shape=3D"_x0000_s24579" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:84.45%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Podano 2 cykle CHT w dawkach </span><span style=3D'position:absolute;top:31.0%;left:9.73%;width= :84.45%; height:7.5%'>zredukowanych o 10% </span><span style=3D'position:absol= ute; top:39.5%;left:9.73%;width:84.45%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Uzyskano zmniejszenie dolegliwości<span style=3D'mso-spacerun:yes'> </span></span><sp= an style=3D'position:absolute;top:46.5%;left:9.73%;width:100.74%;height:7.5%'= >bólowych, obniżenie poziomu PSA do 62ng/ml </span><span style=3D'position:a= bsolute; top:55.25%;left:9.73%;width:94.0%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-3.98%'>•</span>Tolerancja leczenia = dobra, bez toksyczności </span><span style=3D'position:absolute;top:62.25%; left:9.73%;width:84.45%;height:7.5%'>>WHO II</span></div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0032.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 32.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D2009-10-08> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"25"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s25602" type=3D= "#_x0000_m1026" 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grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s25603" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:98.31%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-3.8%'>•</span>W trakcie pobytu w do= mu ok. 10 dnia po CHT </span><span style=3D'position:absolute;top:31.0%;left:9.73= %; width:100.0%;height:7.5%'>zawał mięśnia sercowego zakończony zgonem </span><span style=3D'position:absolute;top:38.0%; left:9.73%;width:91.94%;height:7.5%'>(pacjent z wieloletnim wywiadem choro= by </span><span style=3D'position:absolute;top:45.25%;left:9.73%;width:89.51%;height:7.5%'= >wieńcowej i nadciśnienia) – zdarzenia nie </span><span style=3D'position:= absolute; top:52.25%;left:9.73%;width:84.45%;height:7.5%'>wiążemy z CHT= 3;</span> <div style=3D'position:absolute;top:60.75%;left:5.99%;width:88.2%;height:7= .5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span><span style=3D'mso-special-format:lastCR;display:none'> </span></span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0045.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 45.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Poziomy PSA w kolejnych badaniach od początku C= HT Oznaczenia co 3-4 tyg"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"26"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; 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style=3D'position:absolute; top:1.5%;left:2.05%;width:95.88%;height:8.25%'><span style=3D'font-size:82= %'>Poziomy PSA w kolejnych badaniach od </span></span><span style=3D'position:absolut= e; top:9.5%;left:5.99%;width:88.2%;height:8.25%'><span style=3D'font-size:82%= '>początku CHT </span><span style=3D'font-size:109%'><br> </span></span><span style=3D'position:absolute;top:17.5%;left:5.99%;width= :88.2%; height:5.75%'><span style=3D'font-size:55%'>Oznaczenia co 3-4 tyg</span></= span></div> <p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s2= 6627" type=3D"#_x0000_m1027" style=3D'position:absolute;left:35.5pt;top:125.75p= t; width:649pt;height:357.125pt;visibility:visible' o:spt=3D"75" o:preferrel= ative=3D"t" o:gfxdata=3D"UEsDBBQABgAIAAAAIQAUr971LwEAAOACAAATAAAAW0NvbnRlbnRfVHlwZXNd= LnhtbKRSy27CMBC8 V+o/WL5W2MChqqoEDg09tlVFP8CyNw81fshrAvx9N4EcQCogcbFlrWZmZ8bZcmdb1kHExrucz8SU M3Dam8ZVOf9Zv09eOMOknFGtd5DzPSBfLh4fsvU+ADJCO8x5nVJ4lRJ1DVah8AEcTUofrUr0jJUM 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v:shape=3D"_x0000_s27650" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Pacjent II</div> <div v:shape=3D"_x0000_s27651" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:87.26%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.29%'>•</span>72 letni pracownik fizyczny, mieszkaniec </span><span style=3D'position:absolute;top:31.0%; left:9.73%;width:84.45%;height:7.5%'>małego miasta w woj. śląskim </span><span style=3D'position:absolute;top:39.5%; left:9.73%;width:97.37%;height:7.5%'><span class=3DBB style=3D'position:ab= solute; left:-3.84%'>•</span>Przez 50 lat palił ok. 20 papierosów dziennie, </span><span style=3D'position:absolute;top:46.5%;left:9.73%; width:84.45%;height:7.5%'>od 5 lat nie pali </span><span style=3D'posi= tion: absolute;top:55.25%;left:9.73%;width:84.45%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Bez istotnych klinic= znie chorób </span><span style=3D'position:absolute;top:62.25%;left:9.73= %; width:84.45%;height:7.5%'>współistniejących </span><s= pan style=3D'position:absolute;top:70.75%;left:9.73%;width:84.45%;height:7.5%'= ><span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Rozpoznan= ie raka prostaty ustalono w </span><span style=3D'position:absolute;top:77.75%; left:9.73%;width:92.88%;height:7.5%'>stadium rozsiewu<span style=3D'mso-spacerun:yes'> </span>do kości w 70 roku życi= a </span> <div style=3D'position:absolute;top:86.5%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Histologi= czny stopień Gleason 8 </span></div> <div style=3D'position:absolute;top:95.0%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span> </span></div> <div style=3D'position:absolute;top:103.5%;left:5.99%;width:88.2%;height:7= .5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span><span style=3D'mso-special-format:lastCR;display:none'> </span></span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0034.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 34.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Wywiad Pacjent II"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"28"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s28674" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s28675" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s28674" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Wywiad Pacjent II</div> <div v:shape=3D"_x0000_s28675" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:97.56%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-3.83%'>•</span>Leczony : pełna blokada hormonalna (Analog </span><span style=3D'position:absolute;top:31.= 0%; left:9.73%;width:99.62%;height:7.5%'>GN-RH + Bicalutamid) przez okres 22 miesięcy </span><span style=3D'position:absolute;top:39.5%;left:9= .73%; width:84.45%;height:7.5%'><span class=3DBB style=3D'position:absolute;left= :-4.43%'>•</span>Przy pojawieniu się bólów kostnych i </span><span style=3D'position:absolute;top:46.5%;left:9.73%;width:93.63%;height:7.5%'>= narastaniu poziomu PSA hormonoterapia II </span><span style=3D'position:absolute; top:53.75%;left:9.73%;width:84.45%;height:7.5%'>rzutu – nieskuteczna </span><span style=3D'position:absolute;top:62.25%;left:9= .73%; width:93.25%;height:7.5%'><span class=3DBB style=3D'position:absolute;left= :-4.01%'>•</span>Z cechami hormonooporności (poziom PSA<span style=3D'mso-spacerun:yes'>= </span></span><span style=3D'position:absolute;top:69.25%;left:9.73%;width= :96.25%; height:7.5%'>211ng/ml, poziom testosteronu kastracyjny) </span><span style=3D'position:absolute;top:76.5%;left:9.73%;width:94.56%;height:7.5%'>= oraz progresją kliniczną zakwalifikowany do </span><span style=3D'position:absolute;top:83.5%;left:9.73%;width:84.45%;height:7.5%'>= CHT</span></div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0035.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 35.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Pacjent II: CHT"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"29"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s29698" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s29699" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s29698" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Pacjent II:<span style=3D'mso-spacerun:yes'> </span>CHT</div> <div v:shape=3D"_x0000_s29699" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:84.45%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Otrzymał łącznie 8 cykli Docetaxel + </span><span style=3D'position:absol= ute; top:31.0%;left:9.73%;width:84.45%;height:7.5%'>Prednison. </span><span style=3D'position:absolute;top:39.5%;left:9.73%;width:92.69%;height:7.5%'>= <span class=3DBB style=3D'position:absolute;left:-4.04%'>•</span>Tolerancja leczenia dobra. Ostatnie II cykle </span><span style=3D'position:absolute; top:46.5%;left:9.73%;width:90.26%;height:7.5%'>opóźnione o tydzień z powodu leukopenii </span><span style=3D'position:absolu= te; top:55.25%;left:9.73%;width:90.26%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.14%'>•</span>Stopniowy spadek PSA do<span style=3D'mso-spacerun:yes'> </span>wartości rzędu = </span><span style=3D'position:absolute;top:62.25%;left:9.73%;width:90.44%;height:7.5%'= >20ng/ml po 6 cyklu, następnie stabilizacja </span> <div style=3D'position:absolute;top:70.75%;left:5.99%;width:99.25%;height:= 7.5%'><span style=3D'position:absolute;top:0%;left:3.77%;width:96.22%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-3.92%'>•</span>Całk= owite ustąpienie dolegliwości bólowych</span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0036.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 36.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Pacjent II"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"30"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s30722" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s30723" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s30722" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Pacjent II</div> <div v:shape=3D"_x0000_s30723" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:97.19%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-3.85%'>•</span>Po 8 cyklach wobec b= raku „spadku PSA” oraz </span><span style=3D'position:absolute; top:31.0%;left:9.73%;width:87.82%;height:7.5%'>dobrego samopoczucia pacjent odmówił </span><span style=3D'position:absolute;top:38.0%; left:9.73%;width:84.45%;height:7.5%'>kontynuacji leczenia </span> <div style=3D'position:absolute;top:46.5%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Nie wyraz= ił zgody na hormonoterapię </span></div> <div style=3D'position:absolute;top:55.25%;left:5.99%;width:88.2%;height:7= .5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Nie zgłaszał się do kontroli </span></div> <span style=3D'position:absolute;top:63.75%;left:9.73%;width:100.0%;height= :7.5%'><span class=3DBB style=3D'position:absolute;left:-3.74%'>•</span>Po 9 miesiącach z nasilonymi bólami kostnymi </span><span style=3D'position:absolute;top:70.75%;left:9.73%;width:84.45%;height:7.5%'= >oraz PSA> 1000 zgłosił się do kontroli. </span><span style=3D'position:absolute;top:79.25%;left:9.73%;width:95.69%;height:7.5%'= ><span class=3DBB style=3D'position:absolute;left:-3.91%'>•</span>W badania= ch obrazowych – progresja zmian </span><span style=3D'position:absolute; top:86.5%;left:9.73%;width:84.45%;height:7.5%'>osteosklerotycznych </s= pan> <div style=3D'position:absolute;top:95.0%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span><span style=3D'mso-special-format:lastCR;display:none'> </span></span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0037.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 37.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Pacjent II"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"31"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" 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</span> <div style=3D'position:absolute;top:46.5%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Do chwili= obecnej otrzymał 3 cykle </span></div> <span style=3D'position:absolute;top:55.25%;left:9.73%;width:91.38%;height= :7.5%'><span class=3DBB style=3D'position:absolute;left:-4.09%'>•</span>Spadek po= ziomu PSA z >1000 do 786 i 470 </span><span style=3D'position:absolute;top:62= .25%; left:9.73%;width:84.45%;height:7.5%'>ng/ml </span> <div style=3D'position:absolute;top:70.75%;left:5.99%;width:88.2%;height:7= .5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Tolerancja leczenia dobra.</span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: 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v:shape=3D"_x0000_s33794" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Podsumowanie</div> <div v:shape=3D"_x0000_s33795" class=3DB> <div style=3D'position:absolute;top:24.0%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span> </span></div> <div style=3D'position:absolute;top:32.5%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span> </span></div> <span style=3D'position:absolute;top:41.0%;left:9.73%;width:84.45%;height:= 7.5%'><span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Więk= szość pacjentów<span style=3D'mso-spacerun:yes'> </span>z HRCP to s= tarsi </span><span style=3D'position:absolute;top:48.0%;left:9.73%;width:84.45%;height:7.5%'>= mężczyźni z typowymi dla tego wieku </span><span style=3D'position:absolute;top:55.2= 5%; left:9.73%;width:88.2%;height:7.5%'>współistniejącymi<span style=3D'mso-spacerun:yes'> </span>schorzeniami głównie = </span><span style=3D'position:absolute;top:62.25%;left:9.73%;width:84.45%;height:7.5%'= >układu krążenia </span> <div style=3D'position:absolute;top:70.75%;left:5.99%;width:88.2%;height:7= .5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span><span style=3D'mso-special-format:lastCR;display:none'> </span></span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0056.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 56.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Podsumowanie Docetaxel w HR= PC"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"34"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s34818" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s34819" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s34818" class=3DT><span style=3D'position:absolute; top:2.5%;left:5.99%;width:88.2%;height:10.25%'>Podsumowanie<br> </span><span style=3D'position:absolute;top:12.25%;left:5.99%;width:88.2%; height:10.25%'>Docetaxel w HRPC</span></div> <div v:shape=3D"_x0000_s34819" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:88.76%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.21%'>•</span>Dobra tolerancja lec= zenia pomimo wieku </span><span style=3D'position:absolute;top:31.0%;left:9.73%; width:84.45%;height:7.5%'>pacjentów </span><span style=3D'posit= ion: absolute;top:39.5%;left:9.73%;width:86.32%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.33%'>•</span>Terapia ze stosunkowo niewielką ilością </span><span style=3D'position:absolute; top:46.5%;left:9.73%;width:84.45%;height:7.5%'>istotnych klinicznie działań ubocznych </span><span style=3D'position:absolute; top:55.25%;left:9.73%;width:98.12%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-3.81%'>•</span>Zysk kliniczny u zna= cznego odsetka leczonych </span><span style=3D'position:absolute;top:62.25%;left:= 9.73%; width:91.38%;height:7.5%'>zarówno w czasie do progresji jak i <b>ja= kości </b></span><span style=3D'position:absolute;top:69.25%;left:9.73%;width:84= .45%; height:7.5%'><b>życia. </b></span><span style=3D'position:absolut= e; top:77.75%;left:9.73%;width:98.87%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-3.78%'>•</span>Możliwoś&#= 263; ponownej CHT - korzystna opcja w </span><span style=3D'position:absolute; top:85.0%;left:9.73%;width:84.45%;height:7.5%'>terapii HRPC </span> <div style=3D'position:absolute;top:93.5%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span><span style=3D'mso-special-format:lastCR;display:none'> </span></span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0051.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 51.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: ASCO 2009"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"35"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s35842" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s35843" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s35842" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>ASCO 2009</div> <div v:shape=3D"_x0000_s35843" class=3DB> <div style=3D'text-align:center'><span style=3D'position:absolute;top:24.0= %; left:5.99%;width:88.2%;height:9.25%'><span style=3D'mso-special-format:nob= ullet; display:none;font-family:Arial'>•</span><span style=3D'font-size:125= %'><span style=3D'mso-spacerun:yes'> </span>Standardem w leczeniu= HRPC </span></span><span style=3D'position:absolute;top:32.75%;left:8.05%;width:87.64%;height:9.25%= '><span style=3D'font-size:125%'>pozostaje docetaxel + Prednison </span></span= ></div> <div style=3D'text-align:center;position:absolute;top:43.5%;left:5.99%; width:88.2%;height:9.25%'><span style=3D'mso-special-format:nobullet;displ= ay: none;font-family:Arial'>•</span><span style=3D'font-size:125%;displa= y: none'> </span></div> <div style=3D'text-align:center'><span style=3D'position:absolute;top:54.0= %; left:-.18%;width:100.56%;height:9.25%'><span style=3D'mso-special-format:n= obullet; display:none;font-family:Arial'>•</span><span style=3D'font-size:125= %'>Próby kojarzenia docetaxelu z innymi </span></span><span style=3D'position:absol= ute; top:63.0%;left:9.73%;width:84.45%;height:9.25%'><span style=3D'font-size:1= 25%'>substancjami</span></span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0057.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 57.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Rak prostaty Nowe aspekty ASCO 2009"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"36"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s36866" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s36867" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s36866" class=3DT><span style=3D'position:absolute; top:2.5%;left:5.99%;width:88.2%;height:10.25%'>Rak prostaty <br> </span><span style=3D'position:absolute;top:12.25%;left:5.99%;width:88.2%; height:10.25%'>Nowe aspekty ASCO 2009</span></div> <div v:shape=3D"_x0000_s36867" class=3DB> <div style=3D'position:absolute;top:24.0%;left:5.99%;width:88.2%;height:6.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'font-size:88%'><span class=3DBB style=3D'position:absolute;left:-= 4.43%'>•</span></span><span style=3D'font-size:88%'>Wewnątrzguzowa synteza androgenów = </span></span></div> <span style=3D'position:absolute;top:31.5%;left:9.73%;width:93.07%;height:= 6.5%'><span style=3D'font-size:88%'><span class=3DBB style=3D'position:absolute;left:-= 4.02%'>•</span></span><span style=3D'font-size:88%'>Wzmożenie wrażliwości (upregulation) receptora </span></span><span style=3D'position:absolute;top:37.75%;left:9= .73%; width:90.26%;height:6.5%'><span style=3D'font-size:88%'>androgenowego w przerzutowym raku prostaty </span></span><span style=3D'position:abso= lute; top:45.0%;left:5.99%;width:97.94%;height:6.5%'><span style=3D'mso-special-= format: nobullet;display:none;font-family:Arial'>•</span><span style=3D'font= -size: 88%'><span style=3D'mso-spacerun:yes'> </span>Powyższe wyniki uzasadniają dwa bieżące trendy = </span></span><span style=3D'position:absolute;top:51.25%;left:9.73%;width:90.63%;height:6.5%'= ><span style=3D'font-size:88%'>rozwoju leków dla przerzutowego raka gruczołu </span></span><span style=3D'position:absolute;top:57.5%; left:9.73%;width:97.75%;height:6.5%'><span style=3D'font-size:88%'>krokowe= go znajdujące się w fazie badań klinicznych </span></span> <div style=3D'position:absolute;top:65.0%;left:5.99%;width:88.2%;height:6.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'font-size:88%'><span class=3DBB style=3D'position:absolute;left:-= 4.43%'>•</span></span><span style=3D'font-size:88%'>Nowy antyandrogen MDV3100 </span></span></div> <div style=3D'position:absolute;top:72.5%;left:5.99%;width:88.2%;height:6.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'font-size:88%'><span class=3DBB style=3D'position:absolute;left:-= 4.43%'>•</span></span><span style=3D'font-size:88%'>Inhibitor CYP17 -abirateron </span></span></di= v> <div style=3D'position:absolute;top:80.0%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span><span style=3D'mso-special-format:lastCR;display:none'> </span></span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0052.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 52.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Nowe terapie ASCO 2009"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script 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v:shape=3D"_x0000_s37890" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Nowe terapie ASCO 2009</div> <div v:shape=3D"_x0000_s37891" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:93.44%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.0%'>•</span>Receptor androgenowy pozostaje istotnym </span><span style=3D'position:absolute;top:31.0%;left:= 9.73%; width:84.45%;height:7.5%'>celem terapeutycznym nawet w HRPC </span><sp= an style=3D'position:absolute;top:39.5%;left:9.73%;width:97.94%;height:7.5%'>= <span class=3DBB style=3D'position:absolute;left:-3.82%'>•</span>MDV3100 j= est obiecującym antyandrogenem </span><span style=3D'position:absolute; top:46.5%;left:9.73%;width:88.01%;height:7.5%'>o mechaniźmie działania odmiennym niż </span><span style=3D'position:absolute; top:53.75%;left:9.73%;width:88.76%;height:7.5%'>bicalutamid, aktywnym w HR= PC zarówno </span><span style=3D'position:absolute;top:60.75%;left:9.7= 3%; width:84.45%;height:7.5%'>przed jak i po chemioetrapii </span> <div style=3D'position:absolute;top:69.25%;left:5.99%;width:88.2%;height:7= .5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Preparat w trakcie badań klinicznych</span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0053.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId 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style=3D'font-size:94%'>Immunoterapia w leczeniu HRPC nie wykazała </span></span><span style=3D'position:abso= lute; top:28.25%;left:9.73%;width:84.45%;height:7.0%'><span style=3D'font-size:9= 4%'>wpływu na ból, poziomy PSA lub chorobę </span></span><span style=3D'position:absolute;top:33.5%;left:9.73%;width:84.45%;height:7.0%'>= <span style=3D'font-size:94%'>mierzalną </span></span></div> <div class=3DB style=3D'mso-line-spacing:"80 20 0"'><span style=3D'position= :absolute; top:40.25%;left:9.73%;width:87.26%;height:7.0%'><span style=3D'font-size:9= 4%'><span style=3D'mso-special-format:bullet;position:absolute;left:-4.29%;font-fami= ly: Arial'>•</span></span><span style=3D'font-size:94%'>TYM NIEMNIEJ = 211; nieoczekiwanie wykazano </span></span><span style=3D'position:absolute; top:45.5%;left:9.73%;width:95.13%;height:7.0%'><span style=3D'font-size:94= %'>poprawę przeżyć całkowitych w 3 badaniach III </span></span><span style=3D'position:absolute;top:50.75%;left:9.73%;width:84.45%;height:7.0%'= ><span style=3D'font-size:94%'>fazy: </span></span></div> <div class=3DB1 style=3D'mso-line-spacing:"80 20 0";position:absolute;top:= 57.5%; left:11.04%;width:83.14%;height:6.0%'><span style=3D'position:absolute; top:0%;left:3.6%;width:96.17%;height:100.0%'><span style=3D'font-size:93%'= ><span style=3D'mso-special-format:bullet;position:absolute;left:-3.74%;font-fami= ly: Arial'>–</span></span><span style=3D'font-size:93%'><span style=3D'mso-spacerun:yes'> </span>Sipuleucel-T </span></span></= div> <div class=3DB1 style=3D'mso-line-spacing:"80 20 0"'><span style=3D'positi= on:absolute; top:63.25%;left:14.04%;width:86.7%;height:6.0%'><span style=3D'font-size:9= 3%'><span style=3D'mso-special-format:bullet;position:absolute;left:-3.45%;font-fami= ly: Arial'>–</span></span><span style=3D'font-size:93%'>sugerowana jest także przy użyciu PROSTVAC-VF-</span></span><span style=3D'posit= ion: absolute;top:68.0%;left:14.04%;width:79.96%;height:6.0%'><span style=3D'font-size:93%'>Tricom </span></span></div> <div class=3DB style=3D'text-align:center;mso-line-spacing:"80 20 0";posit= ion: absolute;top:73.75%;left:5.99%;width:88.2%;height:7.0%'><span style=3D'mso-special-format:nobullet;display:none;font-family:Arial'>̶= 6;</span><span style=3D'font-size:94%;color:red'>„BYĆ MOŻE IMMUNOTERAPIA DZIAŁA” </span></div> <div class=3DB style=3D'text-align:center;mso-line-spacing:"80 20 0";posit= ion: absolute;top:80.25%;left:5.99%;width:88.2%;height:4.75%'><span style=3D'mso-special-format:nobullet;display:none;font-family:Arial'>̶= 6;</span><span style=3D'font-size:63%'><i>(komentarz prowadzącego sesję)</i></s= pan><span style=3D'font-size:63%;mso-special-format:lastCR;display:none'><i> </i= ></span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/master01.htm 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g_scaleInFrame||(IsWin("PPTSld") && parent.IsFullScrMode() ) ) document.body.scroll=3D"no" _RSW() if( IsWin("PPTSld") && parent.IsFullScrMode() ) FullScrInit(); =09 MakeSldVis(); ChkAutoAdv() if( runAnimations ) { if( document.all("NSPlay") ) document.all("NSPlay").autoStart =3D false; if( sld.filters && sld.filters.revealtrans ) setTimeout( "document.body.start()", sld.filters.revealtrans.duration * = 1000 ); else document.body.start(); } } function MakeSldVis() { var fTrans=3Dg_showAnimation && SldHasTrans() if( fTrans ) { if( g_bgSound ) { idx=3Dg_bgSound.indexOf(","); pptSound.src=3Dg_bgSound.substr( 0, idx ); pptSound.loop=3D -(parseInt(g_bgSound.substr(idx+1))); } SlideObj.filters.revealtrans.Apply() } SlideObj.style.visibility=3D"visible" if( fTrans ) SlideObj.filters.revealtrans.Play() } function MakeNotesVis() { if( !IsNts() ) return false SlideObj.style.display=3D"none" nObj =3D document.all.item("NotesObj") parent.SetHasNts(0) if( nObj ) { nObj.style.display=3D"" parent.SetHasNts(1) } return 1 } function ChkAutoAdv() { if(SldHasTrans()) SlideObj.onfilterchange=3DAutoAdv else AutoAdv() } function AutoAdv() { if(!IsWin("PPTSld") || !gUseSldTimings )return var sld=3DGetCurSld() if( (sld.mAdvDelay>0) && !parent.IsFramesMode() ) setTimeout("parent.GoToNextSld()",sld.mAdvDelay) } function GetObj(id) { if(g_supportsPPTHTML) return document.all(id); else return document.getElementById(id); } function SldHasTrans() { return SlideObj.style.filter !=3D ""; } function GetSldId() { return sId=3Dlocation.href.substring(location.href.la= stIndexOf('/')+1) } function HideMenu() { if( frames["PPTSld"] && PPTSld.document.all.item("ctx= tmenu") && PPTSld.ctxtmenu.style.display!=3D"none" ) { PPTSld.ctxtmenu.styl= e.display=3D'none'; return true } return false } function IsWin( name ) { return window.name =3D=3D name } function IsNts() { return IsWin("PPTNts") } function IsSldOrNts() { return( IsWin("PPTSld")||IsWin("PPTNts") ) } function SupportsPPTAnimation() { return( navigator.platform =3D=3D "Win32"= && navigator.appVersion.indexOf("Windows")>0 ) } function SupportsPPTHTML() { var appVer=3Dnavigator.appVersion, msie=3DappVer.indexOf("MSIE "), ver=3D0 if( msie >=3D 0 ) ver=3DparseFloat( appVer.substring( msie+5, appVer.indexOf(";",msie) ) ) else ver=3DparseInt(appVer) return( ver >=3D 4 && msie >=3D 0 ) } function _RSW() { if( !g_supportsPPTHTML || IsNts() || ( !g_scaleInFrame && (!IsWin("PPTSld") || !parent.IsFullScrMode()) ) ) return var padding=3D0; if( IsWin("PPTSld") && parent.IsFramesMode() ) padding=3D6 cltWidth=3Ddocument.body.clientWidth-padding cltHeight=3Ddocument.body.clientHeight-padding factor=3D(1.0*cltWidth)/g_origW if( cltHeight < g_origH*factor ) factor=3D(1.0*cltHeight)/g_origH newSize =3D g_origSz * factor if( newSize < 1 ) newSize=3D1 s=3DSlideObj.style s.fontSize=3DnewSize+"px" s.posWidth=3Dg_origW*factor s.posHeight=3Dg_origH*factor s.posLeft=3D(cltWidth-s.posWidth+padding)/2 s.posTop=3D(cltHeight-s.posHeight+padding)/2 if( g_scaleHyperlinks ) ScaleHyperlinks( factor ) } function _InitAnimations() { animRuntimeInstalled =3D ''+document.body.localTime !=3D 'undefined'; isFullScreen =3D (window.name =3D=3D "PPTSld") && !parent.IsFramesMode(); g_animUseRuntime =3D g_showAnimation && animRuntimeInstalled && !(isFullSc= reen && parent.IsSldVisited()); if( g_animUseRuntime ) { collSeq =3D document.all.tags("seq"); if( collSeq !=3D null ) { for(ii=3D0;ii<collSeq.length;ii++) { if( collSeq[ii].getAttribute( "p:nodeType" ) =3D=3D "mainSeq" ) { g_animMainSequence =3D collSeq[ii]; break; } } } if( g_animItemsToHide && document.body.playAnimations !=3D false ) { for(jj =3D 0; jj < g_animItemsToHide.length; jj++) { if( hideObj =3D GetObj(g_animItemsToHide[jj]) ) hideObj.runtimeStyle.visibility=3D"hidden"; } } if( g_animInteractiveItems ){ for(jj =3D 0; jj < g_animInteractiveItems.length; jj++) { if( triggerObj =3D GetObj(g_animInteractiveItems[jj]) ) triggerObj.runtimeStyle.cursor=3D"hand"; } } if( gUseSldTimings && ''+g_animSlideTime !=3D 'undefined' ) { adjustedTime =3D document.body.calculateAutoAdvanceTimes( g_animSlideTim= e, g_animEffectTimings ); if( IsWin("PPTSld") && adjustedTime !=3D g_animSlideTime ) { var sld =3D GetCurSld(); sld.mAdvDelay =3D adjustedTime * 1000; } } } return g_animUseRuntime; } gSldJump =3D 0, gSldJumpTrack =3D 0, gSldJumpIdx =3D ""; function _KPH() { if( IsNts() ) return; if( !parent.IsFramesMode() && event.keyCode =3D=3D 27 && !HideMenu() ) parent.window.close( self ); else if( event.keyCode =3D=3D 32 ) { if( window.name =3D=3D "PPTSld" ) parent.PPTSld.DocumentOnClick(); else parent.GoToNextSld(); } CatchNumKeys( parent, event ); } function CatchNumKeys( win, event ) { if( win.IsFullScrMode() && (48<=3Devent.keyCode) && (event.keyCode<=3D57) = ) { gSldJump =3D 1; gSldJumpIdx +=3D (event.keyCode-48).toString(); } if( win.IsFullScrMode() && gSldJump && event.keyCode =3D=3D 13 ) { var numSlds =3D parent.GetSldList().mList.length if ( gSldJumpIdx > numSlds ) gSldJumpIdx =3D numSlds; if ( gSldJumpIdx >=3D 0 ) { if ( gSldJumpIdx =3D=3D 0 ) gSldJumpIdx =3D 1; var jumpTo =3D parseInt(gSldJumpIdx); gSldJump =3D 0; gSldJumpIdx =3D ""; win.GoToSld( parent.GetSldList().mList[jumpTo-1].mSldHref ) } } } function _KDH() { if( event.keyCode =3D=3D 8 ) { event.returnValue =3D 0; parent.GoToPrevSld(); } } function DocumentOnClick() { if( IsNts() || parent.HideMenu() ) return; if( ( g_allowAdvOnClick && (window.name=3D=3D"PPTSld") && !parent.IsFrames= Mode() ) || (event && event.keyCode=3D=3D32) ) { if( g_animUseRuntime && g_animMainSequence && g_animMainSequence.cangonex= t ) return; parent.GoToNextSld(); } } var g_supportsPPTHTML =3D SupportsPPTHTML(), g_scaleInFrame =3D 1, gId=3D""= , g_bgSound=3D"", g_scaleHyperlinks =3D false, g_allowAdvOnClick =3D 1, g_showInBrowser = =3D 0, gLoopCont =3D 0, gUseSldTimings =3D 1; var g_showAnimation =3D g_supportsPPTHTML && SupportsPPTAnimation() && ( (w= indow.name=3D=3D"PPTSld" && !parent.IsFramesMode()) || g_showInBrowser );va= r g_animManager =3D null; var g_animUseRuntime =3D false; var g_animItemsToHide, g_animInteractiveItems, g_animSlideTime; var g_animMainSequence =3D null; var ENDSHOW_MESG=3D"Koniec pokazu slajdów, kliknij, aby zakończ= yć.", SCREEN_MODE=3D"Frames", gIsEndShow=3D0, NUM_VIS_SLDS=3D37, SCRIP= T_HREF=3D"script.js", FULLSCR_HREF=3D"fullscreen.htm"; var gCurSld =3D gPrevSld =3D 1, g_offset =3D 0, gNtsOpen =3D gHasNts =3D gO= tlTxtExp =3D 0, gHasNarration =3D 0, gOtlOpen =3D true window.gPPTHTML=3DSupportsPPTHTML() var gMainDoc=3Dnew Array(new hrefList("slide0001.htm",1,-1,1),new hrefList(= "slide0047.htm",1,-1,1),new hrefList("slide0048.htm",1,-1,1),new hrefList("= slide0002.htm",1,-1,1),new hrefList("slide0003.htm",1,-1,1),new hrefList("s= lide0054.htm",1,-1,1),new hrefList("slide0055.htm",1,-1,1),new hrefList("sl= ide0049.htm",1,-1,1),new hrefList("slide0023.htm",1,-1,1),new hrefList("sli= de0020.htm",1,-1,1),new hrefList("slide0025.htm",1,-1,1),new hrefList("slid= e0021.htm",1,-1,1),new hrefList("slide0022.htm",1,-1,1),new hrefList("slide= 0038.htm",1,-1,1),new hrefList("slide0040.htm",1,-1,1),new hrefList("slide0= 041.htm",1,-1,1),new hrefList("slide0026.htm",1,-1,1),new hrefList("slide00= 39.htm",1,-1,1),new hrefList("slide0027.htm",1,-1,1),new hrefList("slide002= 8.htm",1,-1,1),new hrefList("slide0029.htm",1,-1,1),new hrefList("slide0030= .htm",1,-1,1),new hrefList("slide0031.htm",1,-1,1),new hrefList("slide0032.= htm",1,-1,1),new hrefList("slide0045.htm",1,-1,1),new hrefList("slide0033.h= tm",1,-1,1),new hrefList("slide0034.htm",1,-1,1),new hrefList("slide0035.ht= m",1,-1,1),new hrefList("slide0036.htm",1,-1,1),new hrefList("slide0037.htm= ",1,-1,1),new hrefList("slide0046.htm",1,-1,1),new hrefList("slide0024.htm"= ,1,-1,1),new hrefList("slide0056.htm",1,-1,1),new hrefList("slide0051.htm",= 1,-1,1),new hrefList("slide0057.htm",1,-1,1),new hrefList("slide0052.htm",1= ,-1,1),new hrefList("slide0053.htm",1,-1,1)); function FullScrInit() { g_allowAdvOnClick =3D GetCurSld().mAdvOnClk document.body.style.backgroundColor=3D"black" document.oncontextmenu=3Dparent._CM; document.onkeydown =3D _KDH; document.ondragstart=3DCancel document.onselectstart=3DCancel self.focus() } function Redirect( frmId ) { var str=3Ddocument.location.hash,idx=3Dstr.indexOf('#'), sId=3DGetSldId() if(idx>=3D0) str=3Dstr.substr(1); if( window.name !=3D frmId && ( sId !=3D str) ) { obj =3D GetObj("Main-File") window.location.href=3Dobj.href+"#"+sId return 1 } return 0 } var MHTMLPrefix =3D CalculateMHTMLPrefix(); function CalculateMHTMLPrefix() { if ( document.location.protocol =3D=3D 'mhtml:') { href=3Dnew String(document.location.href) Start=3Dhref.indexOf('!')+1 End=3Dhref.lastIndexOf('/')+1 if (End < Start) return href.substring(0, Start) else return href.substring(0, End) } return ''; } function GetTags(base,tag) { if(g_supportsPPTHTML) return base.all.tags(tag); else return base.getElementsByTagName(tag); } function UpdNtsPane(){ if(frames["PPTNts"]) PPTNts.location.replace( MHTMLP= refix+GetHrefObj( gCurSld ).mNtsHref ) } function UpdNavPane( sldIndex ){ if(gNavLoaded) PPTNav.UpdNav() } function UpdOtNavPane(){ if(gOtlNavLoaded) PPTOtlNav.UpdOtlNav() } function UpdOtlPane(){ if(gOtlLoaded) PPTOtl.UpdOtl() } function SetHasNts( fVal ) { if( gHasNts !=3D fVal ) { gHasNts=3DfVal UpdNavPane() } } function ToggleOtlText() { gOtlTxtExp=3D!gOtlTxtExp UpdOtlPane() } function ClearMedia() { if (PPTSld.pptSound) PPTSld.pptSound.loop =3D 0; } function FullScreen() { if ( PPTSld.g_animUseRuntime ) PPTSld.document.body.pause(); ClearMedia(); var href =3D ( document.location.protocol =3D=3D 'mhtml:') ? FULLSCR_HREF = : FULLSCR_HREF+"#"+GetHrefObj(gCurSld).mSldHref; if(PPTNav.event.ctrlKey) { var w =3D (window.screen.availWidth * 1.0) / 2.0 var h =3D w * (PPTSld.g_origH * 1.0) / PPTSld.g_origW win =3D window.open( MHTMLPrefix+href,null,"toolbar=3D0,resizable=3D1,top= =3D0,left=3D0," + "width=3D"+ w + ",height=3D" + h ); if( win.document.body && PPTSld.g_animUseRuntime ) win.document.body.PPTSldFrameset=3Dwindow; } else { win =3D window.open( MHTMLPrefix+href,null,"fullscreen=3Dyes" ); if( win.document.body && PPTSld.g_animUseRuntime ) win.document.body.PPTSldFrameset=3Dwindow; } } function ToggleVNarration() { rObj=3DPPTSld.document.all("NSPlay") if( rObj && !PPTSld.g_animUseRuntime ) { if( (rObj.playState =3D=3D 1)||(rObj.playState =3D=3D 0) ) rObj.Play() else if( rObj.playState =3D=3D 2 ) rObj.Pause() else return; } else if( PPTSld.g_animUseRuntime ) { narObj =3D PPTSld.document.all("narrationID") if( narObj ) narObj.togglePause() } } function GetCurSldNum() { obj=3DGetHrefObj(gCurSld) if( obj.mOrigVis =3D=3D 1 ) return obj.mSldIdx else return gCurSld } function GetNumSlds() { if( GetHrefObj(gCurSld).mOrigVis =3D=3D 1 ) return GetSldList().mNumVisSlds; else return GetSldList().mList.length } function GetSldNum( href ) { for(ii=3D0; ii<GetSldList().mList.length; ii++) { if ( GetSldList().mList[ii].mSldHref =3D=3D href ) return ii+1 } return 1 } function GetHrefObj( sldIdx ){ return GetSldList().mList[sldIdx-1] } function IsFramesMode(){ return ( SCREEN_MODE =3D=3D "Frames" ) } function IsFullScrMode(){ return ( SCREEN_MODE =3D=3D "FullScreen" ) } function GoToNextSld() { ii=3DgCurSld + 1 if( GetHrefObj( ii-1 ).mOrigVis =3D=3D 0 ) { if( ii<=3DGetSldList().mList.length ) { obj=3DGetHrefObj(ii) obj.mVis=3D1 GoToSldNum(ii) return } } else { obj=3DGetHrefObj( ii ) while ( obj && ( obj.mOrigVis =3D=3D 0 ) ) obj=3DGetHrefObj(++ii) if( obj && obj.mOrigVis ) { GoToSldNum(ii) return } } if( gSldStack.length > 1 ) PopSldList(); else if( !IsFramesMode() ) { if( gLoopCont ) GoToFirst() else EndShow() } } function GoToPrevSld() { ii=3DgCurSld-1 if( ii > 0 ) { obj=3DGetHrefObj(ii) while ( obj && ( obj.mVis =3D=3D 0 ) && ( ii>0 ) ) obj=3DGetHrefObj(--ii) if( ii =3D=3D 0 ) ii=3D1 GoToSldNum(ii) } } function GoToFirst(){ GoToSld( GetHrefObj(1).mSldHref ) } function GoToLast() { ii=3DGetSldList().mList.length if( ii !=3D gCurSld ) GoToSld( GetHrefObj(ii).mSldHref ) } function GoToSldNum( num ) { if( PPTSld.event ) PPTSld.event.cancelBubble=3Dtrue obj =3D GetHrefObj( num ) obj.mVis=3D1 gPrevSld=3DgCurSld gCurSld =3D num; PPTSld.location.replace(MHTMLPrefix+obj.mSldHref) if( IsFramesMode() ) { UpdNavPane(); UpdOtlPane(); UpdNtsPane() } } function GoToSld( href ) { if( PPTSld.event ) PPTSld.event.cancelBubble=3Dtrue GetHrefObj( GetSldNum(href) ).mVis=3D1 PPTSld.location.replace(MHTMLPrefix+href) } function SldUpdated( id ) { if( id =3D=3D GetHrefObj(gCurSld).mSldHref ) return gPrevSld=3DgCurSld gCurSld=3DGetSldNum(id) if( IsFramesMode() ) { UpdNavPane(); UpdOtlPane(); UpdNtsPane() } } function PrevSldViewed(){ GoToSld( GetHrefObj(gPrevSld).mSldHref ) } function HasPrevSld() { return ( gIsEndShow || ( gCurSld !=3D 1 && GetHrefO= bj( gCurSld-1 ).mVis =3D=3D 1 )||( GetCurSldNum() > 1 ) ) } function HasNextSld() { return (GetCurSldNum() !=3D GetNumSlds()) } function CloseWindow() { if( HideMenu() ) return; var event =3D PPTSld.event; if( !IsFramesMode() && event && (event.keyCode=3D=3D27 || event.keyCode=3D= =3D32 || event.type=3D=3D"click" ) ) window.close( self ); CatchNumKeys( self, event ); } function Unload() { gIsEndShow=3D0; } function SetupEndShow() { gIsEndShow=3D1; PPTSld.document.body.scroll=3D"no"; PPTSld.document.onkeypress=3DCloseWindow; PPTSld.document.onclick=3DCloseWindow; PPTSld.document.oncontextmenu=3D_CM; } function EndShow() { if( IsFramesMode() ) return if( PPTSld.event ) PPTSld.event.cancelBubble=3Dtrue doc=3DPPTSld.document var dir =3D doc.body.dir if( dir !=3D "rtl" ) dir =3D "ltr"; doc.open() doc.writeln('<html><body dir=3D' + dir + ' bgcolor=3Dblack onload=3Dparent= .SetupEndShow() onunload=3Dparent.Unload()><center><p><font face=3DTahoma c= olor=3Dwhite size=3D2><br><b>' + ENDSHOW_MESG + '</b></font></p></center></= body></html>') doc.close() } function SetSldVisited(){ GetSldList().mList[gCurSld-1].mVisited=3Dtrue } function IsSldVisited(){ return GetSldList().mList[gCurSld-1].mVisited } function hrefList( sldHref, visible, advDelay, advClk ) { this.mSldHref=3D this.mNtsHref =3D sldHref this.mOrigVis=3D this.mVis =3D visible this.mVisited=3D false this.mAdvDelay=3D advDelay this.mAdvOnClk=3D advClk } function SldList(arr,curSld,fEnd) { this.mCurSld =3D curSld; this.mList =3D new Array(); var idx =3D 1; for(ii=3D0;ii<arr.length;ii++) { this.mList[ii] =3D new hrefList( arr[ii].mSldHref, arr[ii].mOrigVis, arr[= ii].mAdvDelay, arr[ii].mAdvOnClk ); if( arr[ii].mOrigVis ) this.mList[ii].mSldIdx =3D idx++; } this.mNumVisSlds =3D idx-1; this.fEndShow =3D fEnd; } function GetSldList() { return gSldStack[gSldStack.length-1] } function GetCurSld() { return parent.GetSldList().mList[parent.gCurSld - 1]= } gSldStack =3D new Array(); gSldStack[0] =3D new SldList(gMainDoc,gCurSld,1) function ToggleOtlPane() { frmset=3Ddocument.all("PPTHorizAdjust") frm=3Ddocument.all("PPTOtl") if( gOtlOpen ) frmset.cols=3D"*,100%" else frmset.cols=3D"25%,*" gOtlOpen=3D!gOtlOpen frm.noResize=3D!frm.noResize UpdOtNavPane() } function ToggleNtsPane() { frmset=3Ddocument.all("PPTVertAdjust") frm=3Ddocument.all("PPTNts") if( gNtsOpen ) frmset.rows=3D"100%,*" else frmset.rows=3D"*,20%" gNtsOpen=3D!gNtsOpen UpdNtsPane() } function ViewCustomShow(idx,fEnd) { if( !IsFullScrMode() ) return; var sldList =3D new Array(); var custShow =3D custShowList[idx-1]; var jj =3D 0; for( ii=3D0;ii<custShow.length;ii++ ) { if( custShow[ii] <=3D gMainDoc.length ) sldList[jj++] =3D gMainDoc[custShow[ii]-1]; } if (sldList.length > 0) { PushSldList(sldList,fEnd); gCurSld =3D 1; } else if( PPTSld.event ) PPTSld.event.cancelBubble=3Dtrue } function PushSldList(arr,fEnd) { var ii =3D gSldStack.length; gSldStack[ii] =3D new SldList(arr,gCurSld,fEnd); GoToSld( gSldStack[ii].mList[0].mSldHref ); } function PopSldList() { if (gSldStack[gSldStack.length-1].fEndShow) EndShow() else { gCurSld =3D gSldStack[gSldStack.length-1].mCurSld; gSldStack[gSldStack.length-1] =3D null; gSldStack.length--; var sldList =3D gSldStack[gSldStack.length-1]; GoToSld( sldList.mList[gCurSld - 1].mSldHref ); } } var custShowList=3Dnew Array(); function ImgBtn( oId,bId,w,action ) { var t=3Dthis t.Perform =3D _IBP t.SetActive =3D _IBSetA t.SetInactive=3D _IBSetI t.SetPressed =3D _IBSetP t.SetDisabled=3D _IBSetD t.Enabled =3D _IBSetE t.ChangeIcon =3D null t.UserAction =3D action t.ChgState =3D _IBUI t.mObjId =3D oId t.mBorderId=3D bId t.mWidth =3D w t.mIsOn =3D t.mCurState =3D 0 } function _IBSetA() { if( this.mIsOn ) { obj=3Dthis.ChgState( gHiliteClr,gShadowClr,2 ) obj.style.posTop=3D0 } } function _IBSetI() { if( this.mIsOn ) { obj=3Dthis.ChgState( gFaceClr,gFaceClr,1 ) obj.style.posTop=3D0 } } function _IBSetP() { if( this.mIsOn ) { obj=3Dthis.ChgState( gShadowClr,gHiliteClr,2 ) obj.style.posLeft+=3D1; obj.style.posTop+=3D1 } } function _IBSetD() { obj=3Dthis.ChgState( gFaceClr,gFaceClr,0 ) obj.style.posTop=3D0 } function _IBSetE( state ) { var t=3Dthis GetObj( t.mBorderId ).style.visibility=3D"visible" if( state !=3D t.mIsOn ) { t.mIsOn=3Dstate if( state ) t.SetInactive() else t.SetDisabled() } } function _IBP() { var t=3Dthis if( t.mIsOn ) { if( t.UserAction !=3D null ) t.UserAction() if( t.ChangeIcon ) { obj=3DGetObj(t.mObjId) if( t.ChangeIcon() ) obj.style.posLeft=3Dobj.style.posLeft+(t.mCurState-4)*t.mWidth else obj.style.posLeft=3Dobj.style.posLeft+(t.mCurState-0)*t.mWidth } t.SetActive() } } function _IBUI( clr1,clr2,nextState ) { var t=3Dthis SetBorder( GetObj( t.mBorderId ),clr1,clr2 ) obj=3DGetObj( t.mObjId ) obj.style.posLeft=3Dobj.style.posLeft+(t.mCurState-nextState)*t.mWidth-obj= .style.posTop t.mCurState=3DnextState return obj } function TxtBtn( oId,oeId,action,chkState ) { var t=3Dthis t.Perform =3D _TBP t.SetActive =3D _TBSetA t.SetInactive=3D _TBSetI t.SetPressed =3D _TBSetP t.SetDisabled=3D _TBSetD t.SetEnabled =3D _TBSetE t.GetState =3D chkState t.UserAction =3D action t.ChgState =3D _TBUI t.mObjId =3D oId t.m_elementsId=3D oeId t.mIsOn =3D 1 } function _TBSetA() { var t=3Dthis if( t.mIsOn && !t.GetState() ) t.ChgState( gHiliteClr,gShadowClr,0,0 ) } function _TBSetI() { var t=3Dthis if( t.mIsOn && !t.GetState() ) t.ChgState( gFaceClr,gFaceClr,0,0 ) } function _TBSetP() { if( this.mIsOn ) this.ChgState( gShadowClr,gHiliteClr,1,1 ) } function _TBSetD() { this.ChgState( gFaceClr,gFaceClr,0,0 ) this.mIsOn =3D 0 } function _TBSetE() { var t=3Dthis if( !t.GetState() ) t.ChgState( gFaceClr,gFaceClr,0,0 ) else t.ChgState( gShadowClr,gHiliteClr,1,1 ) t.mIsOn =3D 1 } function _TBP() { var t=3Dthis if( t.mIsOn ) { if( t.UserAction !=3D null ) t.UserAction() if( !t.GetState ) return if( t.GetState() ) t.SetPressed() else t.SetActive() } } function _TBUI( clr1,clr2,lOffset,tOffset ) { SetBorder( GetObj( this.mObjId ),clr1,clr2 ) Offset( GetObj( this.m_elementsId ),lOffset,tOffset ) } function Offset( obj, top, left ){ obj.style.top=3Dtop; obj.style.left=3Dle= ft } function SetBorder( obj, upperLeft, lowerRight ) { s=3Dobj.style; s.borderStyle =3D "solid" s.borderWidth =3D 1 s.borderLeftColor =3D s.borderTopColor =3D upperLeft s.borderBottomColor=3D s.borderRightColor =3D lowerRight } function GetBtnObj(){ return gBtnArr[window.event.srcElement.id] } function BtnOnOver(){ b=3DGetBtnObj(); if( b !=3D null ) b.SetActive() } function BtnOnDown(){ b=3DGetBtnObj(); if( b !=3D null ) b.SetPressed() } function BtnOnOut(){ b=3DGetBtnObj(); if( b !=3D null ) b.SetInactive() } function BtnOnUp() { b=3DGetBtnObj() if( b !=3D null ) b.Perform() else Upd() } function GetNtsState(){ return parent.gNtsOpen } function GetOtlState(){ return parent.gOtlOpen } function GetOtlTxtState(){ return parent.gOtlTxtExp } function NtsBtnSetFlag( fVal ) { s=3Ddocument.all.item( this.m_flagId ).style s.display=3D"none" if( fVal ) s.display=3D"" else s.display=3D"none" } function _BSetA_Border(){ b =3D gBtnArr[this.mObjId]; if( b !=3D null ) b.S= etActive() } function _BSetI_Border(){ b =3D gBtnArr[this.mObjId]; if( b !=3D null ) b.S= etInactive() } function _BSetP_Border(){ b =3D gBtnArr[this.mObjId]; if( b !=3D null ) b.S= etPressed() } function _BSetA_BorderImg() { b =3D gBtnArr[this.mBorderId] if( b !=3D null && this.mIsOn && !b.GetState() ) { obj=3Dthis.ChgState( gHiliteClr,gShadowClr,2 ) obj.style.posTop=3D0 } } function _BSetI_BorderImg() { b =3D gBtnArr[this.mBorderId] if( b !=3D null && this.mIsOn && !b.GetState() ) { obj=3Dthis.ChgState( gFaceClr,gFaceClr,1 ) obj.style.posTop=3D0 } } var gHiliteClr=3D"THREEDHIGHLIGHT",gShadowClr=3D"THREEDSHADOW",gFaceClr=3D"= THREEDFACE" var gBtnArr =3D new Array() gBtnArr["nb_otl"] =3D new TxtBtn( "nb_otl","nb_otlElem",parent.ToggleOtlPan= e,GetOtlState ) gBtnArr["nb_otlElem"] =3D new TxtBtn( "nb_otl","nb_otlElem",parent.ToggleOt= lPane,GetOtlState ) gBtnArr["nb_nts"] =3D new ImgBtn( "nb_nts","nb_ntsBorder",10,parent.ToggleN= tsPane ) gBtnArr["nb_nts"].SetActive =3D _BSetA_BorderImg; gBtnArr["nb_nts"].SetInactive =3D _BSetI_BorderImg; gBtnArr["nb_ntsBorder"] =3D new TxtBtn( "nb_ntsBorder","nb_ntsElem",parent.= ToggleNtsPane,GetNtsState ) gBtnArr["nb_ntsElem"] =3D new TxtBtn( "nb_ntsBorder","nb_ntsElem",parent.To= ggleNtsPane,GetNtsState ) gBtnArr["nb_prevBorder"] =3D gBtnArr["nb_prev"]=3D new ImgBtn( "nb_prev","n= b_prevBorder",30,parent.GoToPrevSld ) gBtnArr["nb_nextBorder"] =3D gBtnArr["nb_next"]=3D new ImgBtn( "nb_next","n= b_nextBorder",30,parent.GoToNextSld ) gBtnArr["nb_sldshw"]=3D new ImgBtn( "nb_sldshw","nb_sldshwBorder",18,parent= .FullScreen ) gBtnArr["nb_sldshwBorder"] =3D new TxtBtn( "nb_sldshw","nb_sldshwBorder",pa= rent.FullScreen,null ) gBtnArr["nb_sldshwBorder"].SetActive =3D _BSetA_Border; gBtnArr["nb_sldshwBorder"].SetInactive =3D _BSetI_Border; gBtnArr["nb_sldshwText"] =3D new TxtBtn( "nb_sldshw","nb_sldshwText",parent= .FullScreen,null ) gBtnArr["nb_sldshwText"].SetActive =3D _BSetA_Border; gBtnArr["nb_sldshwText"].SetInactive =3D _BSetI_Border; gBtnArr["nb_voice"] =3D gBtnArr["nb_voiceBorder"] =3D new ImgBtn( "nb_voice= ","nb_voiceBorder",18,parent.ToggleVNarration ) gBtnArr["nb_otlTxtBorder"] =3D gBtnArr["nb_otlTxt"]=3D new ImgBtn( "nb_otlT= xt","nb_otlTxtBorder",23,parent.ToggleOtlText ) gBtnArr["nb_ntsBorder"].m_flagId=3D "nb_nts" gBtnArr["nb_ntsBorder"].SetFlag =3D NtsBtnSetFlag gBtnArr["nb_otlTxt"].ChangeIcon=3D GetOtlTxtState var sNext=3D"Dalej",sPrev=3D"Poprzedni",sEnd=3D"Zakończ pokaz",sFont= =3D"Arial",sArrow=3D"Strzałka",sFreeform=3D"Dowolny kształt",sRec= t=3D"Prostokąt",sOval=3D"Owal" function ShowMenu() { BuildMenu(); var doc=3DPPTSld.document.body,x=3DPPTSld.event.clientX+doc.scrollLeft,y= =3DPPTSld.event.clientY+doc.scrollTop m =3D PPTSld.document.all.item("ctxtmenu") m.style.pixelLeft=3Dx if( (x+m.scrollWidth > doc.clientWidth)&&(x-m.scrollWidth > 0) ) m.style.pixelLeft=3Dx-m.scrollWidth m.style.pixelTop=3Dy if( (y+m.scrollHeight > doc.clientHeight)&&(y-m.scrollHeight > 0) ) m.style.pixelTop=3Dy-m.scrollHeight m.style.display=3D"" } function _CM() { if( !parent.IsFullScrMode() ) return; if(!PPTSld.event.ctrlKey) { ShowMenu() return false } else HideMenu() } function BuildMenu() { if( PPTSld.document.all.item("ctxtmenu") ) return var mObj=3DCreateItem( PPTSld.document.body ) mObj.id=3D"ctxtmenu" mObj.style.visibility=3D"hidden" var s=3DmObj.style s.position=3D"absolute" s.cursor=3D"default" s.width=3D"120px" SetCMBorder(mObj,"menu","black") var iObj=3DCreateItem( mObj ) SetCMBorder( iObj, "threedhighlight","threedshadow" ) iObj.style.padding=3D2 CreateMenuItem( iObj,sNext,M_GoNextSld,M_True ) CreateMenuItem( iObj,sPrev,M_GoPrevSld,M_HasPrevSld ) CreateSeparator( iObj ) CreateMenuItem( iObj,sEnd,M_End,M_True ) mObj.style.visibility=3D"visible" } function Cancel() { window.event.cancelBubble=3Dtrue; window.event.returnVa= lue=3Dfalse } function Highlight() { ChangeClr("activecaption","threedhighlight") } function Deselect() { ChangeClr("threedface","menutext") } function Perform() { e=3DPPTSld.event.srcElement if( e.type=3D=3D"menuitem" && e.IsActive() ) e.Action() else PPTSld.event.cancelBubble=3Dtrue } function ChangeClr( bg,clr ) { e=3DPPTSld.event.srcElement if( e.type=3D=3D"menuitem" && e.IsActive() ) { e.style.backgroundColor=3Dbg e.style.color=3Dclr } } function M_HasPrevSld() { return( parent.HasPrevSld() ) } function M_GoNextSld() { if( gIsEndShow ) M_End(); else GoToNextSld() } function M_GoPrevSld() { if( gIsEndShow ) { gIsEndShow=3D0; history.back();= PPTSld.event.cancelBubble=3Dtrue; } else GoToPrevSld() } function M_True() { return true } function M_End() { window.close( self ) } function CreateMenuItem( node,text,action,eval ) { var e=3DCreateItem( node ) e.type=3D"menuitem" e.Action=3Daction e.IsActive=3Deval e.innerHTML=3Dtext if( !e.IsActive() ) e.style.color=3D"threedshadow" e.onclick=3DPerform e.onmouseover=3DHighlight e.onmouseout=3DDeselect s=3De.style; s.fontFamily=3DsFont s.fontSize=3D"9pt" s.paddingLeft=3D2 } function CreateSeparator( node ) { var sObj=3DCreateItem( node ) SetCMBorder(sObj,"menu","menu") var s=3DsObj.style s.borderTopColor=3D"threedshadow" s.borderBottomColor=3D"threedhighlight" s.height=3D1 s.fontSize=3D"0px" } function CreateItem( node ) { var elem=3DPPTSld.document.createElement("DIV") node.insertBefore( elem ) return elem } function SetCMBorder( o,ltClr,rbClr ) { var s=3Do.style s.backgroundColor=3D"menu" s.borderStyle=3D"solid" s.borderWidth=3D1 s.borderColor=3DltClr+" "+rbClr+" "+rbClr+" "+ltClr } ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/fullscreen.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; 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charset="us-ascii" <html> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf> <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\frame.h= tm" id=3D"webarch_temp_base_tag"> <![endif]><![if !ppt]><script src=3Dscript.js></script><script>  </script>  <![endif]> </head> <frameset rows=3D"*,25" border=3D0> <frameset cols=3D"25%,*" onload=3D"Load()" id=3DPPTHorizAdjust framespacin= g=3D1 frameborder=3D1> <frame src=3Doutline.htm title=3D"Konspekt" name=3DPPTOtl> <frame src=3Dslide0001.htm title=3D"Slajd" name=3DPPTSld> </frameset> <frameset cols=3D"25%,*" framespacing=3D1> <frame src=3Doutline.htm title=3D"Pasek nawigacyjny konspektu" name=3DPPTOtlNav scrolling=3Dno noresize> <frame src=3Doutline.htm title=3D"Pasek nawigacyjny slajdu" name=3DPPTNav scrolling=3Dno noresize> </frameset> </frameset> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/outline.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; 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font-family:Arial;color:buttontext;font-size:9pt; cursor:default'> <img src=3D"notes_flag.gif" id=3D"nb_nts" style=3D'display:none'> No= tatki</div> <div id=3D"nb_ntsBorder" title =3D"Pokaż/Ukryj notatki" onfocus=3D"BtnOnOver()" onblur=3D"BtnOnOut()" TABINDEX=3D1 style= =3D'position:absolute;top:0%;left:0%;width:100%;height:20px'> </div> </td> </table> <table style=3D'position:relative;width:70px' align=3Dright cellpadding=3D0= cellspacing=3D0> <td nowrap> <div id=3D"nb_sldshwText" title=3D"Pokaz slajdów na pełnym ekr= anie" align=3Dcenter style=3D'position:relative;margin-left:20px;padding:3p= x; font-family:Arial;color:buttontext;font-size:9pt;cursor:default'>Pokaz slajdów</div> <div id=3D"nb_sldshwBorder" title=3D"Pokaz slajdów na pełnym ekranie" onfocus=3D"BtnOnOver()" onblur=3D"BtnOnOut()" TABINDEX= =3D5 style=3D'position:absolute;top:0%;left:0%;width:100%;height:20px'> <div style=3D'position:absolute;clip:rect(0px, 18px, 18px, 0px)'><img src=3D"buttons.gif" id=3D"nb_sldshw" style=3D'position:relative;left:-254p= x'></div> </div> </td> <td> <div id=3D"nb_voiceBorder" style=3D'display:none;position:absolute;top:0;l= eft:-40px; width:20px;height:20px' onfocus=3D"BtnOnOver()" onblur=3D"BtnOnOut()" TABI= NDEX=3D4 class=3Dbutton> <div style=3D'position:absolute;clip:rect(0px, 18px, 18px, 0px)'><img src=3D"buttons.gif" id=3D"nb_voice" title=3D"Wstrzymaj/Odtwarzaj narracj&#= 281;" style=3D'position: relative;left:-290px'></div> </div> </td> </table> <table style=3D'position:relative' align=3Dcenter cellpadding=3D0 cellspaci= ng=3D0> <td nowrap> <div id=3D"nb_prevBorder" onfocus=3D"BtnOnOver()" onblur=3D"BtnOnOut()" TA= BINDEX=3D2 class=3Dbutton style=3D'left:-30px'> <div style=3D'position:absolute;clip:rect(0px, 30px, 18px, 0px)'><img src=3D"buttons.gif" id=3D"nb_prev" title=3D"Poprzedni slajd" style=3D'posi= tion:relative; left:0px'></div> </div> <span id=3D"nav_text" style=3D'position:relative;top:3px;width:100px;font-= family: Arial;color:buttontext;font-size:9pt'></span> <div id=3D"nb_nextBorder" onfocus=3D"BtnOnOver()" onblur=3D"BtnOnOut()" TA= BINDEX=3D3 class=3Dbutton> <div style=3D'position:absolute;clip:rect(0px, 30px, 18px, 0px)'><img src=3D"buttons.gif" id=3D"nb_next" title=3D"Następny slajd" style=3D'= position:relative; left:-90px'></div> </div> </td> </table> </div> <div id=3DOtlNavObj onload=3D"Load()" onmouseover=3D"BtnOnOver()" onmousedown=3D"BtnOnDown()" onmouseout=3D"BtnOnOut()" onmouseup=3D"BtnOnUp(= )" onkeypress=3D"ExecBtn()" style=3D'display:none;visibility:hidden'> <table style=3D'position:relative;width:70px' align=3Dleft cellpadding=3D0 = cellspacing=3D0> <td nowrap><div title=3D"Pokaż/Ukryj konspekt" id=3D"nb_otl" onfocus=3D"BtnOnOver()" onblur=3D"BtnOnOut()" TABIN= DEX=3D11 style=3D'position:absolute;top:0%;left:0%;width:100%;height:100%;cursor:de= fault'> <div id=3D"nb_otlElem" align=3Dcenter style=3D'position:relative;padding:3= px;font-family:Arial; color:buttontext;font-size:9pt'>Konspekt</div></div> </td> </table> <table style=3D'position:relative' align=3Dcenter cellpadding=3D0 cellspaci= ng=3D0> <td> <div style=3D'position:absolute;left:-18px;width:24px;height:20px;border-s= tyle: solid;border-width:1px;border-color:threedface' onfocus=3D"BtnOnOver()" on= blur=3D"BtnOnOut()" TABINDEX=3D12 id=3D"nb_otlTxtBorder"> <div style=3D'position:absolute;clip:rect(0px, 22px, 18px, 0px)'><img src=3Dbuttons.gif id=3D"nb_otlTxt" title=3D"Rozwiń/Zwiń konspekt" style=3D'position:relative;left:-157px'></div> </div> </td> </table> </div> <div id=3DOtlObj style=3D'display:none;visibility:hidden;'> <table width=3D"100%" style=3D'font-family:Arial;font-size:9pt'> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>1</font></div> </td> <td width=3D"100%"> <div id=3DPPTP1 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0001.htm');" id=3DPPTL1>Optymalny profil= chorego z HRPC<br> do leczenia chemioterapią</a></font></div> <div id=3DPPTC1 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Wojciech Poborski</li> <li>Oddział Onkologii</li> <li>Szpitala im St. Leszczyńskiego</li> <li>Katowice</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>2</font></div> </td> <td> <div id=3DPPTP2 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0047.htm');" id=3DPPTL2>Zarejestrowane zachorowania na raka prostaty w grupach wiekowych 5 lat w <br> woj. śląskim (2005)</a></font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>3</font></div> </td> <td> <div id=3DPPTP3 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0048.htm');" id=3DPPTL3>Współ= ;czynniki zachorowań na raka prostaty w grupach wiekowych 5 letnich <br> w woj. śląskim (2005)</a></font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>4</font></div> </td> <td> <div id=3DPPTP4 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0002.htm');" id=3DPPTL4>HRPC</a></font><= /div> <div id=3DPPTC4 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Rak gruczołu krokowego rozpoznawany jest zazwyczaj w grupie pacjentów powyżej 60 roku życia.</li> <li>Do powstania hormonooporności dochodzi zazwyczaj po kilku latach leczenia (mediana 18-24 m-cy)</li> <li>Po powstaniu hormonooporności rokowanie jest niekorzystne; czas przeżycia wynosił 9-12 m-cy</li> <li>Petrylak DP. Chemotherapy for the treatment .. w Prostate and renal cancer…. Parthenon Publishing Group 2002</li> <br> <br> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>5</font></div> </td> <td> <div id=3DPPTP5 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0003.htm');" id=3DPPTL5>HRCP</a></font><= /div> <div id=3DPPTC5 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li><span style=3D'mso-spacerun:yes'> </span>Progresja choroby w trakcie hormonoterapii u pacjenta z udokumentowanym rozpoznaniem raka gruczołu krokowego<span style=3D'mso-spacerun:yes'> </span>po wykorzystaniu co najmnie= j II rzutów leczenia</li> <li>I rzut –blokada analogiem GNRH (tzw. pełna blokada nie da= je zysku klinicznego, a tylko większą ilość działań ubocznych)</li> <li>II rzut – antyandrogeny (steroidowe lub niesteroidowe)</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>6</font></div> </td> <td> <div id=3DPPTP6 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0054.htm');" id=3DPPTL6>HRCP</a></font><= /div> <div id=3DPPTC6 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Wskazania do rozpoczęcia terapii:</li> <li>Progresja kliniczna</li> <li>Narastanie poziomu PSA</li> <li>Kastracyjny poziom testosteronu</li> <br> <br> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>7</font></div> </td> <td> <div id=3DPPTP7 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0055.htm');" id=3DPPTL7>Progresja w trak= cie leczenia HRCP</a></font></div> <div id=3DPPTC7 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Obecnie brak standardów postępowania po progresji<span style=3D'mso-spacerun:yes'> </span>po CHT w HRPC</li> <li>Możliwość ponownego zastosowania hormonoterapii</li> <li>Powtórna CHT</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>8</font></div> </td> <td> <div id=3DPPTP8 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0049.htm');" id=3DPPTL8>HRCP</a></font><= /div> <div id=3DPPTC8 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Pacjent z HRPC typowo jest pacjentem starszym, często z licznymi chorobami współistniejącymi.</li> <li>Odpowiedzi terapeutyczne (RR) na klasyczną chemioterapię jedną substancją<span style=3D'mso-spacerun:yes'> </= span>w serii badań wynosiły 8,7%, a mediana przeżycia 9-12 m= -cy*</li> <br> <br> <br> <li>Yagoda A, Petrylak D Cancer 1993;71:1098-109</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>9</font></div> </td> <td> <div id=3DPPTP9 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0023.htm');" id=3DPPTL9>"Doświ= adczenia własne"</a></font></div> <div id=3DPPTC9 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <br> <br> <li>Doświadczenia własne</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>10</font></div> </td> <td> <div id=3DPPTP10 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0020.htm');" id=3DPPTL10>"Do Oś= ;rodka skierowano łącznie 23..."</a></font></div> <div id=3DPPTC10 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li><span style=3D'mso-spacerun:yes'> </span>Do Oś= ;rodka skierowano łącznie 23 chorych spełniających kryt= eria HRPC</li> <li>Do leczenia<span style=3D'mso-spacerun:yes'> </span>chemioterapią<span style=3D'mso-spacerun:yes'> </s= pan>I rzutu zakwalifikowano:</li> <li>21 chorych</li> <li>Wiek 49 do 81 lat</li> <li>Podana ilość cykli 2 do 10 (średnio 5,6), łącznie 117 podań</li> <br> <br> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>11</font></div> </td> <td> <div id=3DPPTP11 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0025.htm');" id=3DPPTL11>Choroby współistniejące<br> istotne klinicznie</a></font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>12</font></div> </td> <td> <div id=3DPPTP12 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0021.htm');" id=3DPPTL12>Tolerancja lecz= enia</a></font></div> <div id=3DPPTC12 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>U 1 pacjenta leukopenia i trombocytopenia WHO III/IV (wiek 81 lat, pomimo zredukowania dawki)</li> <li>Przy 37 cyklach leukopenie ustępujące po odroczeniu cyklu = (o tydzień)</li> <li>Pozostałe objawy uboczne<span style=3D'mso-spacerun:yes'> </span>istotne klinicznie w nasileniu WHO<II</li> <br> <br> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>13</font></div> </td> <td> <div id=3DPPTP13 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0022.htm');" id=3DPPTL13>Odpowiedzi klin= iczne</a></font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>14</font></div> </td> <td> <div id=3DPPTP14 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0038.htm');" id=3DPPTL14>"Prezentac= ja przypadków"</a></font></div> <div id=3DPPTC14 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <br> <li>Prezentacja przypadków</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>15</font></div> </td> <td> <div id=3DPPTP15 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0040.htm');" id=3DPPTL15>Wywiad</a></fon= t></div> <div id=3DPPTC15 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Rozpoznanie ustalono w wieku 67 lat</li> <li>PSA 27 ng/ml, bez cech rozsiewu<span style=3D'mso-spacerun:yes'>&nbs= p; </span>w badaniach obrazowych.</li> <li><span style=3D'mso-spacerun:yes'> </span>Operowany= z założeniem leczenia radykalnego</li> <li>Histologicznie stopień złośliwości Gleason 8, naciekanie torebki stercza</li> <li>Po operacji spadek wartości PSA do 2ng/ml</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>16</font></div> </td> <td> <div id=3DPPTP16 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0041.htm');" id=3DPPTL16>Wywiad c.d.</a>= </font></div> <div id=3DPPTC16 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>W 6 miesięcy po operacji – narastanie poziomu PSA, w CT stwierdzono powiększenie węzłów chłonnych miednicy małej oraz ogniska osteosklerotyczne w kościach miednicy, klinicznie obrzęk kończyny dolnej (ucisk na naczynia)</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>17</font></div> </td> <td> <div id=3DPPTP17 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0026.htm');" id=3DPPTL17>Leczenie</a></f= ont></div> <div id=3DPPTC17 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Włączono pełną blokadę hormonalną (ana= log GN-RH oraz flutamid, a następnie bicalutamid), oraz w zwią= zku z objawami uciskowymi<span style=3D'mso-spacerun:yes'> </span>paliatywną RT</li> <li>Uzyskano ustąpienie dolegliwości klinicznych oraz spadek poziomu PSA < 4ng/ml</li> <li>Po 28 miesiącach leczenia bóle kostne, narastanie<span style=3D'mso-spacerun:yes'> </span>poziomu PSA, zmiany osteoli= tyczno – osteosklerotyczne w kościach miednicy i kręgosłupa.</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>18</font></div> </td> <td> <div id=3DPPTP18 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0039.htm');" id=3DPPTL18>Stwierdzenie HR= PC</a></font></div> <div id=3DPPTC18 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>70 letni pracownik umysłowy, mieszkaniec dużego miasta</li> <li>Choroby współistniejące:</li> <ul> <li>Nadciśnienie tętnicze</li> <li>Choroba wieńcowa (leczony od 15 lat)</li> </ul> <li>Wieloletni palacz tytoniu, od 3 lat nie pali</li> <br> <br> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>19</font></div> </td> <td> <div id=3DPPTP19 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0027.htm');" id=3DPPTL19>Leczenie c.d.</= a></font></div> <div id=3DPPTC19 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Przy przyjęciu:</li> <li>Stan ogólny WHO I/II</li> <li>Nadciśnienie wyrównane lekami, zapis EKG bez cech ostrego niedokrwienia</li> <li>Układ krwiotwórczy, parametry wydolności wątro= by oraz poziom kreatyniny prawidłowe</li> <li>Poziom PSA narastający w ciągu 2 tyg<span style=3D'mso-spacerun:yes'> </span>z 79,8 do 168ng/ml</li> <li>Poziom testosteronu - kastracyjny</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>20</font></div> </td> <td> <div id=3DPPTP20 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0028.htm');" id=3DPPTL20>Chemioterapia</= a></font></div> <div id=3DPPTC20 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Docetaxel + Prednison w pełnych dawkach należnych</li> <li>Po I cyklu znaczące zmniejszenie dolegliwości bólow= ych (odstawiono opioidy)</li> <li>Łącznie IX cykli, bez opóźnień, bez toksyczności >WHO II, z dobra tolerancją</li> <li>Powolny spadek poziomu PSA do VI cyklu, następnie stabilizacja, (bez<span style=3D'mso-spacerun:yes'> </span>normalizacji)</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>21</font></div> </td> <td> <div id=3DPPTP21 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0029.htm');" id=3DPPTL21>Follow-up</a></= font></div> <div id=3DPPTC21 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Wobec braku dalszej regresji poziomu PSA, całkowitego ustąpienia dolegliwości bólowych oraz zmęczenia pacjenta chemioterapią odstąpiono od kontynuacji CHT i podjęto próbę leczenia hormonalnego (analog GN-RH + Bicalutamid) oraz bisfosfoniany.</li> <li>Leczenie prowadzono przez 9 miesięcy; stabily obraz kliniczny, poziom PSA ok. 20 ng/ml</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>22</font></div> </td> <td> <div id=3DPPTP22 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0030.htm');" id=3DPPTL22>Follow-up</a></= font></div> <div id=3DPPTC22 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Po 9 miesiącach progresja: nasilenie dolegliwości bólowych, narastanie PSA</li> <li>Naciek w trzonach kręgów L4 i L5 – stabilizacja operacyjna, a następnie paliatywna RT</li> <li>Wobec narastania objawów chorobowych<span style=3D'mso-spacerun:yes'> </span>w tym dolegliwości bólowych zdecydowano o ponownym włączeniu leczenia cytostatycznego</li> <li>Poziom PSA 210ng/ml</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>23</font></div> </td> <td> <div id=3DPPTP23 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0031.htm');" id=3DPPTL23>CHT – II = rzut</a></font></div> <div id=3DPPTC23 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Podano 2 cykle CHT w dawkach zredukowanych o 10%</li> <li>Uzyskano zmniejszenie dolegliwości<span style=3D'mso-spacerun:yes'> </span>bólowych, obniż= enie poziomu PSA do 62ng/ml</li> <li>Tolerancja leczenia dobra, bez toksyczności >WHO II</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>24</font></div> </td> <td> <div id=3DPPTP24 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0032.htm');" id=3DPPTL24>"W trakcie= pobytu w domu..."</a></font></div> <div id=3DPPTC24 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>W trakcie pobytu w domu ok. 10 dnia po CHT zawał mięś= nia sercowego zakończony zgonem (pacjent z wieloletnim wywiadem cho= roby wieńcowej i nadciśnienia) – zdarzenia nie wiążemy z CHT</li> <br> <br> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>25</font></div> </td> <td> <div id=3DPPTP25 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0045.htm');" id=3DPPTL25>Poziomy PSA w k= olejnych badaniach od początku CHT <br> Oznaczenia co 3-4 tyg</a></font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>26</font></div> </td> <td> <div id=3DPPTP26 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0033.htm');" id=3DPPTL26>Pacjent II</a><= /font></div> <div id=3DPPTC26 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>72 letni pracownik fizyczny, mieszkaniec małego miasta w woj. śląskim</li> <li>Przez 50 lat palił ok. 20 papierosów dziennie, od 5 lat = nie pali</li> <li>Bez istotnych klinicznie chorób współistniejących</li> <li>Rozpoznanie raka prostaty ustalono w stadium rozsiewu<span style=3D'mso-spacerun:yes'> </span>do kości w 70 roku życia</li> <li>Histologiczny stopień Gleason 8</li> <br> <br> <br> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>27</font></div> </td> <td> <div id=3DPPTP27 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0034.htm');" id=3DPPTL27>Wywiad Pacjent = II</a></font></div> <div id=3DPPTC27 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Leczony : pełna blokada hormonalna (Analog GN-RH + Bicalutamid) przez okres 22 miesięcy</li> <li>Przy pojawieniu się bólów kostnych i narastaniu poziomu PSA hormonoterapia II rzutu – nieskuteczna</li> <li>Z cechami hormonooporności (poziom PSA<span style=3D'mso-spacerun:yes'> </span>211ng/ml, poziom testostero= nu kastracyjny) oraz progresją kliniczną zakwalifikowany do C= HT</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>28</font></div> </td> <td> <div id=3DPPTP28 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0035.htm');" id=3DPPTL28>Pacjent II:<span style=3D'mso-spacerun:yes'> </span>CHT</a></font></div> <div id=3DPPTC28 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Otrzymał łącznie 8 cykli Docetaxel + Prednison.</li> <li>Tolerancja leczenia dobra. Ostatnie II cykle opóźnione o tydzień z powodu leukopenii</li> <li>Stopniowy spadek PSA do<span style=3D'mso-spacerun:yes'> </span>wartości rzędu 20ng/ml po 6 cyklu, następnie stabilizacja</li> <li>Całkowite ustąpienie dolegliwości bólowych</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>29</font></div> </td> <td> <div id=3DPPTP29 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0036.htm');" id=3DPPTL29>Pacjent II</a><= /font></div> <div id=3DPPTC29 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Po 8 cyklach wobec braku „spadku PSA” oraz dobrego samopoczucia pacjent odmówił kontynuacji leczenia</li> <li>Nie wyraził zgody na hormonoterapię</li> <li>Nie zgłaszał się do kontroli</li> <li>Po 9 miesiącach z nasilonymi bólami kostnymi oraz PSA> 1000 zgłosił się do kontroli.</li> <li>W badaniach obrazowych – progresja zmian osteosklerotycznych</= li> <br> <br> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>30</font></div> </td> <td> <div id=3DPPTP30 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0037.htm');" id=3DPPTL30>Pacjent II</a><= /font></div> <div id=3DPPTC30 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Włączono ponownie chemioterapię: Docetaxel (dawka zredukowana o 15% - uprzednie leukopenie) wraz z Prednisonem.</li> <li>Do chwili obecnej otrzymał 3 cykle</li> <li>Spadek poziomu PSA z >1000 do 786 i 470 ng/ml</li> <li>Tolerancja leczenia dobra.</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>31</font></div> </td> <td> <div id=3DPPTP31 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0046.htm');" id=3DPPTL31>Pacjent II<br> Poziomy PSA w trakcie CHT<br> Oznaczenia co 3-4<span style=3D'mso-spacerun:yes'> </span>tyg</a>= </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>32</font></div> </td> <td> <div id=3DPPTP32 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0024.htm');" id=3DPPTL32>Podsumowanie</a= ></font></div> <div id=3DPPTC32 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <br> <br> <li>Większość pacjentów<span style=3D'mso-spacerun:yes'> </span>z HRCP to starsi mężczyźni z typowymi dla tego wieku współistniejącymi<span style=3D'mso-spacerun:yes'>&= nbsp; </span>schorzeniami głównie układu krążen= ia</li> <br> <br> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>33</font></div> </td> <td> <div id=3DPPTP33 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0056.htm');" id=3DPPTL33>Podsumowanie<br> Docetaxel w HRPC</a></font></div> <div id=3DPPTC33 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Dobra tolerancja leczenia pomimo wieku pacjentów</li> <li>Terapia ze stosunkowo niewielką ilością istotnych klinicznie działań ubocznych</li> <li>Zysk kliniczny u znacznego odsetka leczonych zarówno w czasie= do progresji jak i jakości życia.</li> <li>Możliwość ponownej CHT - korzystna opcja w terapii HR= PC</li> <br> <br> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>34</font></div> </td> <td> <div id=3DPPTP34 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0051.htm');" id=3DPPTL34>ASCO 2009</a></= font></div> <div id=3DPPTC34 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li><span style=3D'mso-spacerun:yes'> </span>Standarde= m w leczeniu HRPC pozostaje docetaxel + Prednison</li> <br> <br> <li>Próby kojarzenia docetaxelu z innymi substancjami</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>35</font></div> </td> <td> <div id=3DPPTP35 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0057.htm');" id=3DPPTL35>Rak prostaty <b= r> Nowe aspekty ASCO 2009</a></font></div> <div id=3DPPTC35 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Wewnątrzguzowa synteza androgenów</li> <li>Wzmożenie wrażliwości (upregulation) receptora androgenowego w przerzutowym raku prostaty</li> <li><span style=3D'mso-spacerun:yes'> </span>Powyższe wyniki uzasadniają dwa bieżące trendy rozwoju leków dla przerzutowego raka gruczołu krokowego znajdujące się w fazie badań klinicznych</l= i> <li>Nowy antyandrogen MDV3100</li> <li>Inhibitor CYP17 -abirateron</li> <br> <br> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>36</font></div> </td> <td> <div id=3DPPTP36 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0052.htm');" id=3DPPTL36>Nowe terapie AS= CO 2009</a></font></div> <div id=3DPPTC36 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Receptor androgenowy pozostaje istotnym celem terapeutycznym nawet w HRPC</li> <li>MDV3100 jest obiecującym antyandrogenem o mechaniźmie działania odmiennym niż bicalutamid, aktywnym w HRPC zarówno przed jak i po chemioetrapii</li> <li>Preparat w trakcie badań klinicznych</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>37</font></div> </td> <td> <div id=3DPPTP37 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0053.htm');" id=3DPPTL37>Nowe terapie AS= CO 2009<br> immunoterapia</a></font></div> <div id=3DPPTC37 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Immunoterapia w leczeniu HRPC nie wykazała wpływu na ból, poziomy PSA lub chorobę mierzalną</li> <li>TYM NIEMNIEJ – nieoczekiwanie wykazano poprawę przeżyć całkowitych w 3 badaniach III fazy:</li> <ul> <li><span style=3D'mso-spacerun:yes'> </span>Sipuleucel-T</li> <li>sugerowana jest także przy użyciu PROSTVAC-VF-Tricom</li> </ul> <li>„BYĆ MOŻE IMMUNOTERAPIA DZIAŁA”</li> <li>(komentarz prowadzącego sesję)</li> </ul> </font></div> </td> </tr> </table> </div> <div style=3D'display:none'><a href=3D"../OptymalnyprofilchoregozHRCP.htm">= 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Pobierz przeglądarkę obsługującą archiwa sieci Web, na przykład program Windows® Internet Explorer®. ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e>  <link rel=3DPresentation-XML href=3D"OptymalnyprofilchoregozHRCP_pliki/pres= .xml"> <meta name=3DDescription content=3D"2009-10-08: Optymalny profil chorego z HRPC do leczenia chemiote= rapią"> <meta http-equiv=3Dexpires content=3D0> <![if !ppt]><script>  </script> <![endif]> </head> <body> <script></script><font face=3DArial size=3D2><b> <p>Ta prezentacja zawiera zawartość, którą przeglądarka może nie wyświetlać prawidłowo.</p> <p>Jeśli mimo wszystko chcesz kontynuować, kliknij <a href=3D"OptymalnyprofilchoregozHRCP_pliki/frame.htm">tutaj</a>.</p> </b></font><script></script> </body> </html> ------=_NextPart_01CA4839.6400CBF0 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</span><span style=3D'position:absolute;top:41.75%;left:8.42%;width:83.14= %; height:10.25%'>do leczenia chemioterapią</span></div> <div v:shape=3D"_x0000_s2051"> <div class=3DCB1 style=3D'mso-margin-left-alt:468'></div> <div class=3DCB2 style=3D'mso-margin-left-alt:720'></div> <div class=3DCB3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DCB4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DCB style=3D'mso-line-spacing:"80 20 0";mso-char-wrap:1;mso-ki= nsoku-overflow: 1;position:absolute;top:56.25%;left:15.91%;width:68.16%;height:6.25%'><span style=3D'font-size:84%;color:#898989'>Wojciech Poborski </span></div> <div class=3DCB style=3D'mso-line-spacing:"80 20 0";mso-char-wrap:1;mso-ki= nsoku-overflow: 1;position:absolute;top:62.25%;left:15.91%;width:68.16%;height:6.25%'><span style=3D'font-size:84%;color:#898989'>Oddział Onkologii </span></= div> <div class=3DCB style=3D'mso-line-spacing:"80 20 0";mso-char-wrap:1;mso-ki= nsoku-overflow: 1;position:absolute;top:68.25%;left:15.91%;width:68.16%;height:6.25%'><span style=3D'font-size:84%;color:#898989'>Szpitala im St. Leszczyńskiego&= #13;</span></div> <div class=3DCB style=3D'mso-line-spacing:"80 20 0";mso-char-wrap:1;mso-ki= nsoku-overflow: 1;position:absolute;top:74.25%;left:15.91%;width:68.16%;height:6.25%'><span style=3D'font-size:84%;color:#898989'>Katowice</span></div> </div> <div v:shape=3D"_x0000_s2052"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'text-align:center;mso-char-wrap:1;mso-kinsoku-over= flow: 1;position:absolute;top:94.0%;left:35.2%;width:29.77%;height:3.0%'><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:67%;color:#898989'>Pozna</span><span style=3D'mso-ascii-= font-family: 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top:33.33%;left:3.66%;width:96.33%;height:34.48%'>jest niekorzystne; czas przeżycia wynosił 9-12 </span><span style=3D'position:absolute; top:65.51%;left:3.66%;width:82.75%;height:34.48%'>m-cy </span></div> <div id=3D"_x0000_s5123_280_389" style=3D'mso-char-wrap:1;mso-kinsoku-over= flow: 1;position:absolute;top:91.25%;left:5.99%;width:91.76%;height:3.0%;white-s= pace: nowrap'><span style=3D'mso-special-format:nobullet;display:none;font-famil= y: Arial'>•</span><span style=3D'font-size:38%'>Petrylak DP. Chemothera= py for the treatment .. w Prostate and renal cancer…. Parthenon Publishing Group 2002 </span></div> <div style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1;position:absolute; top:95.25%;left:5.99%;width:88.2%;height:7.5%'><span style=3D'position:abs= olute; top:0%;left:4.24%;width:95.75%;height:100.0%'><span style=3D'visibility:hi= dden'><span style=3D'mso-special-format:bullet;position:absolute;left:-4.43%;font-fami= ly: Arial'>•</span></span><span style=3D'mso-special-format:lastCR;displ= ay: none'> </span></span></div> </div> </p:slide></div> <p:animation number=3D"-1740910880"/><oa:par id=3D"TimeNode0" dur=3D"indefi= nite" restart=3D"never" p:nodeType=3D"timingRoot"> <oa:seq id=3D"TimeNode1" dur=3D"indefinite" prev=3D"document.onpptprev" next=3D"document.onpptnext" concurrent=3D"enabled" nextAction=3D"seek" p:nodeType=3D"mainSeq"> <oa:par id=3D"TimeNode2" begin=3D"indefinite" fill=3D"hold"> <oa:par id=3D"TimeNode3" begin=3D"0.0" fill=3D"hold"> <oa:par id=3D"TimeNode4" o:presetID=3D"ppt_22" o:presetClass=3D"entranc= e" 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style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s6146" type=3D"= #_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s6147" type=3D"= #_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s6146" class=3DT style=3D'mso-char-wrap:1;mso-kinso= ku-overflow: 1;position:absolute;top:7.25%;left:5.99%;width:88.2%;height:10.25%'>HRCP</= div> <div v:shape=3D"_x0000_s6147" class=3DB> <div style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1'><span style=3D'posit= ion: absolute;top:24.0%;left:5.99%;width:104.86%;height:7.5%'><span style=3D'mso-special-format:nobullet;display:none;font-family:Arial'>̶= 6;</span><span style=3D'mso-spacerun:yes'> </span>Progresja choroby w t= rakcie hormonoterapii u </span><span style=3D'position:absolute;top:31.0%;left:9.= 73%; width:99.25%;height:7.5%'>pacjenta z udokumentowanym rozpoznaniem </span><= span style=3D'position:absolute;top:38.0%;left:9.73%;width:101.31%;height:7.5%'= >raka gruczołu krokowego<span style=3D'mso-spacerun:yes'> </span>po wykorzystaniu co </span><span style=3D'position:absolute;top:45.25%;left:9= .73%; width:84.45%;height:7.5%'>najmniej II rzutów leczenia </span></= div> <div style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1'><span style=3D'posit= ion: absolute;top:53.75%;left:9.73%;width:95.69%;height:7.5%'><span style=3D'mso-special-format:bullet;position:absolute;left:-3.91%;font-fami= ly: Arial'>•</span>I rzut –blokada analogiem GNRH (tzw. pełna= </span><span style=3D'position:absolute;top:60.75%;left:9.73%;width:91.01%;height:7.5%'= >blokada nie daje zysku klinicznego, a tylko </span><span style=3D'position:absolut= e; top:68.0%;left:9.73%;width:84.45%;height:7.5%'>większą ilość działań ubocznych) </span></div> <div style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1'><span style=3D'posit= ion: absolute;top:76.5%;left:9.73%;width:85.95%;height:7.5%'><span style=3D'mso-special-format:bullet;position:absolute;left:-4.35%;font-fami= ly: Arial'>•</span>II rzut – antyandrogeny (steroidowe lub </span>= <span style=3D'position:absolute;top:83.5%;left:9.73%;width:84.45%;height:7.5%'>= niesteroidowe)</span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0054.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 54.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: HRCP"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap 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adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s7171" type=3D"= #_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s7170" class=3DT style=3D'position:absolute;top:7.2= 5%; left:5.99%;width:88.2%;height:10.25%'>HRCP</div> <div v:shape=3D"_x0000_s7171" class=3DB> <div style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1;position:absolute; top:24.0%;left:5.99%;width:88.2%;height:7.5%'><span style=3D'mso-special-f= ormat: nobullet;display:none;font-family:Arial'>•</span>Wskazania do rozpoczęcia terapii: </div> <div style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1;position:absolute; top:32.5%;left:5.99%;width:88.2%;height:7.5%'><span style=3D'position:abso= lute; top:0%;left:4.24%;width:95.75%;height:100.0%'><span style=3D'mso-special-f= ormat: bullet;position:absolute;left:-4.43%;font-family:Arial'>•</span>Prog= resja kliniczna </span></div> <div style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1;position:absolute; top:41.0%;left:5.99%;width:88.2%;height:7.5%'><span style=3D'position:abso= lute; top:0%;left:4.24%;width:95.75%;height:100.0%'><span style=3D'mso-special-f= ormat: bullet;position:absolute;left:-4.43%;font-family:Arial'>•</span>Nara= stanie poziomu PSA </span></div> <div style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1;position:absolute; top:49.5%;left:5.99%;width:88.2%;height:7.5%'><span style=3D'position:abso= lute; top:0%;left:4.24%;width:95.75%;height:100.0%'><span style=3D'mso-special-f= ormat: bullet;position:absolute;left:-4.43%;font-family:Arial'>•</span>Kast= racyjny poziom testosteronu </span></div> <div style=3D'position:absolute;top:58.0%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span><span style=3D'mso-special-format:lastCR;display:none'> </span></span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0055.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 55.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Progresja w trakcie leczeni= a HRCP"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"8"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s8194" type=3D"= #_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" 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v:shape=3D"_x0000_s8194" class=3DT style=3D'position:absolute;top:7.2= 5%; left:-.37%;width:100.74%;height:10.25%'>Progresja w trakcie leczenia HRCP<= /div> <div v:shape=3D"_x0000_s8195" class=3DB><span style=3D'position:absolute;t= op:24.0%; left:9.73%;width:94.94%;height:7.5%'><span class=3DBB style=3D'position:ab= solute; left:-3.94%'>•</span>Obecnie brak standardów postępowani= a po </span><span style=3D'position:absolute;top:31.0%;left:9.73%;width:84.45%; height:7.5%'>progresji<span style=3D'mso-spacerun:yes'> </span>po CH= T w HRPC </span><span style=3D'position:absolute;top:39.5%;left:9.73%; width:84.45%;height:7.5%'><span class=3DBB style=3D'position:absolute;left= :-4.43%'>•</span>Możliwość ponownego zastosowania </span><span style=3D'position:absolute;top:46.5%; left:9.73%;width:84.45%;height:7.5%'>hormonoterapii </span> <div style=3D'position:absolute;top:55.25%;left:5.99%;width:88.2%;height:7= .5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Powt&oacu= te;rna CHT</span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0049.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 49.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: HRCP"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"9"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s9218" type=3D"= #_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s9219" type=3D"= #_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s9218" class=3DT style=3D'position:absolute;top:7.2= 5%; left:5.99%;width:88.2%;height:10.25%'>HRCP</div> <div v:shape=3D"_x0000_s9219" class=3DB><span style=3D'position:absolute;t= op:24.0%; left:9.73%;width:84.45%;height:7.5%'><span class=3DBB style=3D'position:ab= solute; left:-4.43%'>•</span>Pacjent z HRPC typowo jest pacjentem </span><sp= an style=3D'position:absolute;top:31.0%;left:9.73%;width:84.45%;height:7.5%'>= starszym, często z licznymi chorobami </span><span style=3D'position:absolute; top:38.0%;left:9.73%;width:84.45%;height:7.5%'>współistniej= 61;cymi. </span><span style=3D'position:absolute;top:46.5%;left:9.73%;width:96.81%;height:7.5%'>= <span class=3DBB style=3D'position:absolute;left:-3.86%'>•</span>Odpowiedzi terapeutyczne (RR) na klasyczną </span><span style=3D'position:absolu= te; top:53.75%;left:9.73%;width:100.56%;height:7.5%'>chemioterapię jedn&#= 261; substancją<span style=3D'mso-spacerun:yes'> </span>w serii bada= ń </span><span style=3D'position:absolute;top:60.75%;left:9.73%;width:95.31%; height:7.5%'>wynosiły 8,7%, a mediana przeżycia 9-12 m-</span><s= pan style=3D'position:absolute;top:68.0%;left:9.73%;width:84.45%;height:7.5%'>= cy* </span> <div style=3D'position:absolute;top:76.5%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span> </span></div> <div style=3D'position:absolute;top:85.0%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span> </span></div> <div style=3D'position:absolute;top:92.75%;left:5.99%;width:88.2%;height:2= .75%'><span style=3D'mso-special-format:nobullet;display:none;font-family:Arial'>̶= 6;</span><span style=3D'font-size:34%'>Yagoda A, Petrylak D Cancer 1993;71:1098-109</span= ></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0023.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type 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style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s10242" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"t"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s10243" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s10243" class=3DB> <div style=3D'text-align:center;position:absolute;top:24.0%;left:5.99%; width:88.2%;height:7.5%'><span style=3D'mso-special-format:nobullet;displa= y: none;font-family:Arial'>•</span> </div> <div style=3D'text-align:center;position:absolute;top:32.5%;left:5.99%; width:88.2%;height:7.5%'><span style=3D'mso-special-format:nobullet;displa= y: none;font-family:Arial'>•</span> </div> <div style=3D'text-align:center;position:absolute;top:41.5%;left:5.99%; width:88.2%;height:10.25%'><span style=3D'mso-special-format:nobullet; display:none;font-family:Arial'>•</span><span style=3D'font-size:138= %'>Doświadczenia własne</span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0020.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 20.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D2009-10-08> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"11"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s11266" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"t"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s11267" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s11267" class=3DB><span style=3D'position:absolute; top:24.0%;left:5.99%;width:97.94%;height:7.5%'><span style=3D'mso-special-= format: nobullet;display:none;font-family:Arial'>•</span><span style=3D'mso-spacerun:yes'> </span>Do Ośrodka skier= owano łącznie 23 chorych </span><span style=3D'position:absolute;top:3= 1.0%; left:9.73%;width:84.45%;height:7.5%'>spełniających kryteria HRPC </span><span style=3D'position:absolute;top:39.5%;left:5.99%; width:88.2%;height:7.5%'><span style=3D'mso-special-format:nobullet;displa= y: none;font-family:Arial'>•</span>Do leczenia<span style=3D'mso-spacerun:yes'> </span>chemioterapią<span style=3D'mso-spacerun:yes'> </span>I rzutu </span><span style=3D'pos= ition: absolute;top:46.5%;left:9.73%;width:84.45%;height:7.5%'>zakwalifikowano:&#= 13;</span> <div style=3D'position:absolute;top:55.25%;left:5.99%;width:88.2%;height:7= .5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>21 choryc= h </span></div> <div style=3D'position:absolute;top:63.75%;left:5.99%;width:88.2%;height:7= .5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Wiek 49 d= o 81 lat </span></div> <span style=3D'position:absolute;top:72.25%;left:9.73%;width:85.39%;height= :7.5%'><span class=3DBB style=3D'position:absolute;left:-4.38%'>•</span>Podana ilość cykli 2 do 10 (średnio 5,6), </span><span style=3D'position:absolute;top:79.25%;left:9.73%;width:84.45%;height:7.5%'= >łącznie 117 podań </span> <div style=3D'position:absolute;top:87.75%;left:5.99%;width:88.2%;height:7= .5%'><span style=3D'mso-special-format:nobullet;display:none;font-family:Arial'>̶= 6;</span><span style=3D'mso-special-format:lastCR;display:none'> </span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0025.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type 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style=3D'position:absolute; top:2.5%;left:5.99%;width:88.2%;height:10.25%'>Choroby współistniejące<br> </span><span style=3D'position:absolute;top:12.25%;left:5.99%;width:88.2%; height:10.25%'>istotne klinicznie</span></div> <div v:shape=3D"_x0000_s12292"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1;position:ab= solute; top:24.0%;left:5.99%;width:83.52%;height:8.25%'><span style=3D'font-family= :Calibri; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;font-size:200%; color:white'><b>Nadci</b></span><span style=3D'mso-ascii-font-family:Calib= ri; mso-hansi-font-family:Calibri;font-size:200%;color:white'><b>ś</b></s= pan><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:white'><b>nienie<span style=3D'mso-spacerun:yes'> </span>t</b></span><span style=3D'mso-as= cii-font-family: Calibri;mso-hansi-font-family:Calibri;font-size:200%;color:white'><b>ę= ;</b></span><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:white'><b>tnicze WHO<span style=3D'mso-spacerun:yes'> </span>I-III)</b></span><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:white;mso-special-format:lastCR;display:none'= ><b> </b></span></div> </div> <div v:shape=3D"_x0000_s12293"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'text-align:center;mso-char-wrap:1;mso-kinsoku-over= flow: 1;position:absolute;top:24.0%;left:81.46%;width:12.73%;height:8.25%'><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:white'><b>17</b></span><span style=3D'font-fa= mily: Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri; font-size:200%;color:white;mso-special-format:lastCR;display:none'><b> = ;</b></span></div> </div> <div v:shape=3D"_x0000_s12294"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1;position:ab= solute; top:33.25%;left:5.99%;width:73.59%;height:8.25%'><span style=3D'font-famil= y: Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri; font-size:200%;color:black'>Choroba wie</span><span style=3D'mso-ascii-fon= t-family: Calibri;mso-hansi-font-family:Calibri;font-size:200%;color:black'>ń</= span><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:black'>cowa </span><span style=3D'font-family= :Calibri; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;font-size:200%; color:black;mso-special-format:lastCR;display:none'> </span></div> </div> <div v:shape=3D"_x0000_s12295"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'text-align:center;mso-char-wrap:1;mso-kinsoku-over= flow: 1;position:absolute;top:33.25%;left:81.46%;width:12.73%;height:8.25%'><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:black'>11</span><span style=3D'font-family:Ca= libri; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;font-size:200%; color:black;mso-special-format:lastCR;display:none'> </span></div> </div> <div v:shape=3D"_x0000_s12296"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1;position:ab= solute; top:42.5%;left:5.99%;width:87.26%;height:8.25%'><span style=3D'font-family= :Calibri; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;font-size:200%; color:black'>Niewydolno</span><span style=3D'mso-ascii-font-family:Calibri; mso-hansi-font-family:Calibri;font-size:200%;color:black'>ść</sp= an><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:black'> kr</span><span style=3D'mso-ascii-fon= t-family: Calibri;mso-hansi-font-family:Calibri;font-size:200%;color:black'>ą&#= 380;</span><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:black'>enia (NYHA I i II)</span><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:black;mso-special-format:lastCR;display:none'= > </span></div> </div> <div v:shape=3D"_x0000_s12297"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'text-align:center;mso-char-wrap:1;mso-kinsoku-over= flow: 1;position:absolute;top:42.5%;left:81.46%;width:12.73%;height:8.25%'><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:black'>7</span><span style=3D'font-family:Cal= ibri; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;font-size:200%; color:black;mso-special-format:lastCR;display:none'> </span></div> </div> <div v:shape=3D"_x0000_s12298"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1;position:ab= solute; top:52.0%;left:5.99%;width:73.59%;height:8.25%'><span style=3D'font-family= :Calibri; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;font-size:200%; color:black'>Cukrzyca typ II</span><span style=3D'font-family:Calibri; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;font-size:200%; color:black;mso-special-format:lastCR;display:none'> </span></div> </div> <div v:shape=3D"_x0000_s12299"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'text-align:center;mso-char-wrap:1;mso-kinsoku-over= flow: 1;position:absolute;top:52.0%;left:81.46%;width:12.73%;height:8.25%'><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:black'>5</span><span style=3D'font-family:Cal= ibri; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;font-size:200%; color:black;mso-special-format:lastCR;display:none'> </span></div> </div> <div v:shape=3D"_x0000_s12300"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'mso-char-wrap:1;mso-kinsoku-overflow:1;position:ab= solute; top:61.25%;left:5.99%;width:73.59%;height:8.25%'><span style=3D'font-famil= y: Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri; font-size:200%;color:black'>Inne</span><span style=3D'font-family:Calibri; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;font-size:200%; color:black;mso-special-format:lastCR;display:none'> </span></div> </div> <div v:shape=3D"_x0000_s12301"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'text-align:center;mso-char-wrap:1;mso-kinsoku-over= flow: 1;position:absolute;top:61.25%;left:81.46%;width:12.73%;height:8.25%'><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:200%;color:black'>2</span><span style=3D'font-family:Cal= ibri; 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font-size:222%;color:black'>CR</span><span style=3D'font-family:Calibri; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;font-size:222%; color:black;mso-special-format:lastCR;display:none'> </span></div> </div> <div v:shape=3D"_x0000_s14344"> <div class=3DO1 style=3D'mso-margin-left-alt:468'></div> <div class=3DO2 style=3D'mso-margin-left-alt:720'></div> <div class=3DO3 style=3D'mso-margin-left-alt:1008'></div> <div class=3DO4 style=3D'mso-margin-left-alt:1296'></div> <div class=3DO style=3D'text-align:center;mso-char-wrap:1;mso-kinsoku-over= flow: 1;position:absolute;top:40.25%;left:75.28%;width:13.85%;height:9.25%'><span style=3D'font-family:Calibri;mso-ascii-font-family:Calibri;mso-hansi-font-= family: Calibri;font-size:222%;color:black'>1</span><span style=3D'font-family:Cal= ibri; mso-ascii-font-family:Calibri;mso-hansi-font-family:Calibri;font-size:222%; color:black;mso-special-format:lastCR;display:none'> </span></div> </div> <div v:shape=3D"_x0000_s14345"> <div 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xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 38.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D2009-10-08> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" 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width:88.2%;height:10.25%'><span style=3D'mso-special-format:nobullet; display:none;font-family:Arial'>•</span><span style=3D'font-size:138= %; display:none'> </span></div> <div style=3D'text-align:center;position:absolute;top:35.5%;left:5.99%; width:88.2%;height:10.25%'><span style=3D'mso-special-format:nobullet; display:none;font-family:Arial'>•</span><span style=3D'font-size:138= %'>Prezentacja przypadków</span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0040.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 40.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Wywiad"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"16"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s16386" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s16387" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s16386" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Wywiad</div> <div v:shape=3D"_x0000_s16387" class=3DB> <div style=3D'position:absolute;top:24.0%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Rozpoznan= ie ustalono w wieku 67 lat </span></div> <span style=3D'position:absolute;top:32.5%;left:9.73%;width:100.93%;height= :7.5%'><span class=3DBB style=3D'position:absolute;left:-3.71%'>•</span>PSA 27 ng= /ml, bez cech rozsiewu<span style=3D'mso-spacerun:yes'> </span>w badaniach </= span><span style=3D'position:absolute;top:39.5%;left:9.73%;width:84.45%;height:7.5%'>= obrazowych. </span><span style=3D'position:absolute;top:48.0%;left:5.99%;width:88.2%;height:7.5%'><= span style=3D'mso-special-format:nobullet;display:none;font-family:Arial'>̶= 6;</span><span style=3D'mso-spacerun:yes'> </span>Operowany z założeniem leczenia </span><span style=3D'position:absolute; top:55.25%;left:9.73%;width:84.45%;height:7.5%'>radykalnego </span><sp= an style=3D'position:absolute;top:63.75%;left:9.73%;width:95.88%;height:7.5%'= ><span class=3DBB style=3D'position:absolute;left:-3.9%'>•</span>Histologic= znie stopień złośliwości Gleason 8, </span><span style=3D'position:absolute;top:70.75%;left:9.73%;width:84.45%;height:7.5%'= >naciekanie torebki stercza </span> <div style=3D'position:absolute;top:79.25%;left:5.99%;width:97.37%;height:= 7.5%'><span style=3D'position:absolute;top:0%;left:3.84%;width:96.15%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.0%'>•</span>Po operacj= i spadek wartości PSA do 2ng/ml</span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0041.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 41.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Wywiad c.d."> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"17"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s17410" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s17411" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s17410" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Wywiad c.d.</div> <div v:shape=3D"_x0000_s17411" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:84.45%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>W 6 miesięcy po operacji – narastanie </span><span style=3D'position:absolute;top:31= .0%; left:9.73%;width:100.0%;height:7.5%'>poziomu PSA, w CT stwierdzono powiększenie </span><span style=3D'position:absolute;top:38.0%;left:9= .73%; width:84.83%;height:7.5%'>węzłów chłonnych miednicy małej oraz </span><span style=3D'position:absolute;top:45.25%;left:9.= 73%; width:84.45%;height:7.5%'>ogniska osteosklerotyczne w kościach </span= ><span style=3D'position:absolute;top:52.25%;left:9.73%;width:94.19%;height:7.5%'= >miednicy, klinicznie obrzęk kończyny dolnej </span><span style=3D'position= :absolute; top:59.5%;left:9.73%;width:84.45%;height:7.5%'>(ucisk na naczynia)</span><= /div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0026.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 26.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Leczenie"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"18"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s18434" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s18435" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s18434" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Leczenie</div> <div v:shape=3D"_x0000_s18435" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:98.5%;height:7.5%'><span class=3DBB style=3D'po= sition: absolute;left:-3.8%'>•</span>Włączono pełną blokadę hormonalną (analog </span><span style=3D'position:absolu= te; top:31.0%;left:9.73%;width:84.45%;height:7.5%'>GN-RH oraz flutamid, a następnie </span><span style=3D'position:absolute;top:38.0%;left:9.73= %; width:88.38%;height:7.5%'>bicalutamid), oraz w związku z objawami </s= pan><span style=3D'position:absolute;top:45.25%;left:9.73%;width:84.45%;height:7.5%'= >uciskowymi<span style=3D'mso-spacerun:yes'> </span>paliatywną RT </span><sp= an style=3D'position:absolute;top:53.75%;left:9.73%;width:97.37%;height:7.5%'= ><span class=3DBB style=3D'position:absolute;left:-3.84%'>•</span>Uzyskano ustąpienie dolegliwości klinicznych </span><span style=3D'positi= on: absolute;top:60.75%;left:9.73%;width:84.45%;height:7.5%'>oraz spadek pozio= mu PSA < 4ng/ml </span><span style=3D'position:absolute;top:69.25%; left:9.73%;width:84.45%;height:7.5%'><span class=3DBB style=3D'position:ab= solute; left:-4.43%'>•</span>Po 28 miesiącach leczenia bóle kost= ne, </span><span style=3D'position:absolute;top:76.5%;left:9.73%;width:84.45%;height:7.5%'>= narastanie<span style=3D'mso-spacerun:yes'> </span>poziomu PSA, zmiany </span><span style=3D'position:absolute;top:83.5%;left:9.73%;width:97.94%;height:7.5%'>= osteolityczno – osteosklerotyczne w kościach </span><span style=3D'position:a= bsolute; top:90.75%;left:9.73%;width:84.45%;height:7.5%'>miednicy i kręgosłupa. </span></div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0039.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 39.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Stwierdzenie HRPC"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"19"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s19458" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s19459" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s19458" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Stwierdzenie HRPC</div> <div v:shape=3D"_x0000_s19459"> <div class=3DB><span style=3D'position:absolute;top:24.0%;left:9.73%;width= :92.32%; height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.05%'>R= 26;</span>70 letni pracownik umysłowy, mieszkaniec </span><span style=3D'position:= absolute; top:31.0%;left:9.73%;width:84.45%;height:7.5%'>dużego miasta </s= pan></div> <div class=3DB style=3D'position:absolute;top:39.5%;left:5.99%;width:88.2%; height:7.5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.7= 5%; height:100.0%'><span class=3DBB style=3D'position:absolute;left:-4.43%'>&#= 8226;</span>Choroby współistniejące: </span></div> <div class=3DB1 style=3D'position:absolute;top:48.0%;left:11.04%;width:83.= 14%; height:6.5%'><span style=3D'position:absolute;top:0%;left:3.6%;width:96.17= %; height:100.0%'><span style=3D'mso-special-format:bullet;position:absolute; left:-3.74%;font-family:Wingdings'>Ø</span>Nadciśnienie tętnicze </span></div> <div class=3DB1 style=3D'position:absolute;top:55.5%;left:11.04%;width:83.= 14%; height:6.5%'><span style=3D'position:absolute;top:0%;left:3.6%;width:96.17= %; height:100.0%'><span style=3D'mso-special-format:bullet;position:absolute; left:-3.74%;font-family:Wingdings'>Ø</span>Choroba wieńcowa (leczony od 15 lat) </span></div> <div class=3DB style=3D'position:absolute;top:63.0%;left:5.99%;width:93.82= %; height:7.5%'><span style=3D'position:absolute;top:0%;left:3.99%;width:96.0= %; height:100.0%'><span class=3DBB style=3D'position:absolute;left:-4.15%'>&#= 8226;</span>Wieloletni palacz tytoniu, od 3 lat nie pali </span></div> <div class=3DB style=3D'position:absolute;top:71.5%;left:5.99%;width:88.2%; height:7.5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.7= 5%; height:100.0%'><span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span></span><span style=3D'mso-special-format:lastCR;display:none'> </span></span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0027.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 27.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Leczenie c.d."> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"20"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s20482" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s20483" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s20482" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Leczenie c.d.</div> <div v:shape=3D"_x0000_s20483" class=3DB> <div style=3D'position:absolute;top:24.0%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Przy przyjęciu: </span></div> <div style=3D'position:absolute;top:32.5%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Stan ogólny WHO I/II </span></div> <span style=3D'position:absolute;top:41.0%;left:9.73%;width:93.63%;height:= 7.5%'><span class=3DBB style=3D'position:absolute;left:-4.0%'>•</span>Nadciś= ;nienie wyrównane lekami, zapis EKG </span><span style=3D'position:absolute; top:48.0%;left:9.73%;width:84.45%;height:7.5%'>bez cech ostrego niedokrwienia </span><span style=3D'position:absolute;top:56.5%;left:9= .73%; width:93.82%;height:7.5%'><span class=3DBB style=3D'position:absolute;left= :-3.99%'>•</span>Układ krwiotwórczy, parametry wydolności </span><span style=3D'posit= ion: absolute;top:63.75%;left:9.73%;width:97.19%;height:7.5%'>wątroby oraz poziom kreatyniny prawidłowe </span><span style=3D'position:absol= ute; top:72.25%;left:9.73%;width:96.25%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-3.89%'>•</span>Poziom PSA narastający w ciągu 2 tyg<span style=3D'mso-spacerun:yes'> </span>z 79,8 </span><span style=3D'position:absolute;top:79.25%;left:9.73= %; width:84.45%;height:7.5%'>do 168ng/ml </span> <div style=3D'position:absolute;top:87.75%;left:5.99%;width:88.2%;height:7= .5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Poziom testosteronu - kastracyjny</span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0028.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 28.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Chemioterapia"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"21"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s21506" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s21507" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s21506" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Chemioterapia</div> <div v:shape=3D"_x0000_s21507" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:92.32%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.05%'>•</span>Docetaxel + Predniso= n w pełnych dawkach </span><span style=3D'position:absolute;top:31.0%; left:9.73%;width:84.45%;height:7.5%'>należnych </span><span style=3D'position:absolute;top:39.5%;left:9.73%;width:98.12%;height:7.5%'>= <span class=3DBB style=3D'position:absolute;left:-3.81%'>•</span>Po I cyklu znaczące zmniejszenie dolegliwości </span><span style=3D'positio= n: absolute;top:46.5%;left:9.73%;width:84.45%;height:7.5%'>bólowych (odstawiono <i>opioidy</i>) </span><span style=3D'position:absolute; top:55.25%;left:9.73%;width:84.45%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Łącznie IX cykli, bez opóźnień, bez </span><span style=3D'position:a= bsolute; top:62.25%;left:9.73%;width:88.38%;height:7.5%'>toksyczności >WHO = II, z dobra tolerancją </span><span style=3D'position:absolute;top:70= .75%; left:9.73%;width:91.01%;height:7.5%'><span class=3DBB style=3D'position:ab= solute; left:-4.11%'>•</span>Powolny spadek poziomu PSA do VI cyklu, </span>= <span style=3D'position:absolute;top:77.75%;left:9.73%;width:88.38%;height:7.5%'= >następnie stabilizacja, (bez<span style=3D'mso-spacerun:yes'> </span>normalizacji)<span style=3D'mso-spacerun:yes'> </span></span>= </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0029.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 29.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Follow-up"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"22"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s22530" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s22531" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s22530" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Follow-up</div> <div v:shape=3D"_x0000_s22531" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:93.25%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.01%'>•</span>Wobec braku dalszej regresji poziomu PSA, </span><span style=3D'position:absolute;top:31.0%; left:9.73%;width:100.18%;height:7.5%'>całkowitego ustąpienia dolegliwości bólowych </span><span style=3D'position:absolute; top:38.0%;left:9.73%;width:85.95%;height:7.5%'>oraz zmęczenia pacjenta chemioterapią </span><span style=3D'position:absolute;top:45.25%; left:9.73%;width:88.57%;height:7.5%'>odstąpiono od kontynuacji CHT i podjęto </span><span style=3D'position:absolute;top:52.25%;left:9.73%; width:98.12%;height:7.5%'>próbę leczenia hormonalnego (analog GN-RH </span><span style=3D'position:absolute;top:59.5%;left:9.73%;width:8= 4.45%; height:7.5%'>+ Bicalutamid) oraz bisfosfoniany. </span><span style=3D'position:absolute;top:68.0%;left:9.73%;width:100.56%;height:7.5%'= ><span class=3DBB style=3D'position:absolute;left:-3.72%'>•</span>Leczenie prowadzono przez 9 miesięcy; stabily </span><span style=3D'position:a= bsolute; top:75.0%;left:9.73%;width:88.57%;height:7.5%'>obraz kliniczny, poziom PSA= ok. 20 ng/ml</span></div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0030.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 30.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Follow-up"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"23"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s23554" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s23555" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s23554" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Follow-up</div> <div v:shape=3D"_x0000_s23555" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:84.45%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Po 9 miesiącach progresja: nasilenie </span><span style=3D'position:absolute;top:31.0%; left:9.73%;width:84.45%;height:7.5%'>dolegliwości bólowych, narastanie PSA </span><span style=3D'position:absolute;top:39.5%;left:= 9.73%; width:100.74%;height:7.5%'><span class=3DBB style=3D'position:absolute;lef= t:-3.71%'>•</span>Naciek w trzonach kręgów L4 i L5 – stabilizacja </span><span style=3D'position:absolute;top:46.5%;left:9.73%;width:84.45%;height:7.5%'>= operacyjna, a następnie paliatywna RT </span><span style=3D'position:absolute; top:55.25%;left:9.73%;width:97.56%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-3.83%'>•</span>Wobec narastania objawów chorobowych<span style=3D'mso-spacerun:yes'> </span>w= </span><span style=3D'position:absolute;top:62.25%;left:9.73%;width:93.82%;height:7.5%'= >tym dolegliwości bólowych zdecydowano o </span><span style=3D'posi= tion: absolute;top:69.25%;left:9.73%;width:84.45%;height:7.5%'>ponownym włączeniu leczenia </span><span style=3D'position:absolute;top:7= 6.5%; left:9.73%;width:84.45%;height:7.5%'>cytostatycznego </span> <div style=3D'position:absolute;top:85.0%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Poziom PSA 210ng/ml</span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0031.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 31.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: CHT – II rzut"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"24"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s24578" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s24579" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s24578" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>CHT – II rzut</div> <div v:shape=3D"_x0000_s24579" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:84.45%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Podano 2 cykle CHT w dawkach </span><span style=3D'position:absolute;top:31.0%;left:9.73%;width= :84.45%; height:7.5%'>zredukowanych o 10% </span><span style=3D'position:absol= ute; top:39.5%;left:9.73%;width:84.45%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Uzyskano zmniejszenie dolegliwości<span style=3D'mso-spacerun:yes'> </span></span><sp= an style=3D'position:absolute;top:46.5%;left:9.73%;width:100.74%;height:7.5%'= >bólowych, obniżenie poziomu PSA do 62ng/ml </span><span style=3D'position:a= bsolute; top:55.25%;left:9.73%;width:94.0%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-3.98%'>•</span>Tolerancja leczenia = dobra, bez toksyczności </span><span style=3D'position:absolute;top:62.25%; left:9.73%;width:84.45%;height:7.5%'>>WHO II</span></div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0032.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 32.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D2009-10-08> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"25"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s25602" type=3D= "#_x0000_m1026" 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grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s25603" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:98.31%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-3.8%'>•</span>W trakcie pobytu w do= mu ok. 10 dnia po CHT </span><span style=3D'position:absolute;top:31.0%;left:9.73= %; width:100.0%;height:7.5%'>zawał mięśnia sercowego zakończony zgonem </span><span style=3D'position:absolute;top:38.0%; left:9.73%;width:91.94%;height:7.5%'>(pacjent z wieloletnim wywiadem choro= by </span><span style=3D'position:absolute;top:45.25%;left:9.73%;width:89.51%;height:7.5%'= >wieńcowej i nadciśnienia) – zdarzenia nie </span><span style=3D'position:= absolute; top:52.25%;left:9.73%;width:84.45%;height:7.5%'>wiążemy z CHT= 3;</span> <div style=3D'position:absolute;top:60.75%;left:5.99%;width:88.2%;height:7= .5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span><span style=3D'mso-special-format:lastCR;display:none'> </span></span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0045.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 45.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Poziomy PSA w kolejnych badaniach od początku C= HT Oznaczenia co 3-4 tyg"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"26"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; 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style=3D'position:absolute; top:1.5%;left:2.05%;width:95.88%;height:8.25%'><span style=3D'font-size:82= %'>Poziomy PSA w kolejnych badaniach od </span></span><span style=3D'position:absolut= e; top:9.5%;left:5.99%;width:88.2%;height:8.25%'><span style=3D'font-size:82%= '>początku CHT </span><span style=3D'font-size:109%'><br> </span></span><span style=3D'position:absolute;top:17.5%;left:5.99%;width= :88.2%; height:5.75%'><span style=3D'font-size:55%'>Oznaczenia co 3-4 tyg</span></= span></div> <p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s2= 6627" type=3D"#_x0000_m1027" style=3D'position:absolute;left:35.5pt;top:125.75p= t; width:649pt;height:357.125pt;visibility:visible' o:spt=3D"75" o:preferrel= ative=3D"t" o:gfxdata=3D"UEsDBBQABgAIAAAAIQAUr971LwEAAOACAAATAAAAW0NvbnRlbnRfVHlwZXNd= LnhtbKRSy27CMBC8 V+o/WL5W2MChqqoEDg09tlVFP8CyNw81fshrAvx9N4EcQCogcbFlrWZmZ8bZcmdb1kHExrucz8SU M3Dam8ZVOf9Zv09eOMOknFGtd5DzPSBfLh4fsvU+ADJCO8x5nVJ4lRJ1DVah8AEcTUofrUr0jJUM 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v:shape=3D"_x0000_s27650" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Pacjent II</div> <div v:shape=3D"_x0000_s27651" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:87.26%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.29%'>•</span>72 letni pracownik fizyczny, mieszkaniec </span><span style=3D'position:absolute;top:31.0%; left:9.73%;width:84.45%;height:7.5%'>małego miasta w woj. śląskim </span><span style=3D'position:absolute;top:39.5%; left:9.73%;width:97.37%;height:7.5%'><span class=3DBB style=3D'position:ab= solute; left:-3.84%'>•</span>Przez 50 lat palił ok. 20 papierosów dziennie, </span><span style=3D'position:absolute;top:46.5%;left:9.73%; width:84.45%;height:7.5%'>od 5 lat nie pali </span><span style=3D'posi= tion: absolute;top:55.25%;left:9.73%;width:84.45%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Bez istotnych klinic= znie chorób </span><span style=3D'position:absolute;top:62.25%;left:9.73= %; width:84.45%;height:7.5%'>współistniejących </span><s= pan style=3D'position:absolute;top:70.75%;left:9.73%;width:84.45%;height:7.5%'= ><span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Rozpoznan= ie raka prostaty ustalono w </span><span style=3D'position:absolute;top:77.75%; left:9.73%;width:92.88%;height:7.5%'>stadium rozsiewu<span style=3D'mso-spacerun:yes'> </span>do kości w 70 roku życi= a </span> <div style=3D'position:absolute;top:86.5%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Histologi= czny stopień Gleason 8 </span></div> <div style=3D'position:absolute;top:95.0%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span> </span></div> <div style=3D'position:absolute;top:103.5%;left:5.99%;width:88.2%;height:7= .5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span><span style=3D'mso-special-format:lastCR;display:none'> </span></span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0034.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 34.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Wywiad Pacjent II"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"28"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s28674" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s28675" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s28674" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Wywiad Pacjent II</div> <div v:shape=3D"_x0000_s28675" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:97.56%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-3.83%'>•</span>Leczony : pełna blokada hormonalna (Analog </span><span style=3D'position:absolute;top:31.= 0%; left:9.73%;width:99.62%;height:7.5%'>GN-RH + Bicalutamid) przez okres 22 miesięcy </span><span style=3D'position:absolute;top:39.5%;left:9= .73%; width:84.45%;height:7.5%'><span class=3DBB style=3D'position:absolute;left= :-4.43%'>•</span>Przy pojawieniu się bólów kostnych i </span><span style=3D'position:absolute;top:46.5%;left:9.73%;width:93.63%;height:7.5%'>= narastaniu poziomu PSA hormonoterapia II </span><span style=3D'position:absolute; top:53.75%;left:9.73%;width:84.45%;height:7.5%'>rzutu – nieskuteczna </span><span style=3D'position:absolute;top:62.25%;left:9= .73%; width:93.25%;height:7.5%'><span class=3DBB style=3D'position:absolute;left= :-4.01%'>•</span>Z cechami hormonooporności (poziom PSA<span style=3D'mso-spacerun:yes'>= </span></span><span style=3D'position:absolute;top:69.25%;left:9.73%;width= :96.25%; height:7.5%'>211ng/ml, poziom testosteronu kastracyjny) </span><span style=3D'position:absolute;top:76.5%;left:9.73%;width:94.56%;height:7.5%'>= oraz progresją kliniczną zakwalifikowany do </span><span style=3D'position:absolute;top:83.5%;left:9.73%;width:84.45%;height:7.5%'>= CHT</span></div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0035.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 35.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Pacjent II: CHT"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"29"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s29698" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s29699" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s29698" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Pacjent II:<span style=3D'mso-spacerun:yes'> </span>CHT</div> <div v:shape=3D"_x0000_s29699" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:84.45%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Otrzymał łącznie 8 cykli Docetaxel + </span><span style=3D'position:absol= ute; top:31.0%;left:9.73%;width:84.45%;height:7.5%'>Prednison. </span><span style=3D'position:absolute;top:39.5%;left:9.73%;width:92.69%;height:7.5%'>= <span class=3DBB style=3D'position:absolute;left:-4.04%'>•</span>Tolerancja leczenia dobra. Ostatnie II cykle </span><span style=3D'position:absolute; top:46.5%;left:9.73%;width:90.26%;height:7.5%'>opóźnione o tydzień z powodu leukopenii </span><span style=3D'position:absolu= te; top:55.25%;left:9.73%;width:90.26%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.14%'>•</span>Stopniowy spadek PSA do<span style=3D'mso-spacerun:yes'> </span>wartości rzędu = </span><span style=3D'position:absolute;top:62.25%;left:9.73%;width:90.44%;height:7.5%'= >20ng/ml po 6 cyklu, następnie stabilizacja </span> <div style=3D'position:absolute;top:70.75%;left:5.99%;width:99.25%;height:= 7.5%'><span style=3D'position:absolute;top:0%;left:3.77%;width:96.22%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-3.92%'>•</span>Całk= owite ustąpienie dolegliwości bólowych</span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0036.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 36.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Pacjent II"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"30"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s30722" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s30723" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s30722" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Pacjent II</div> <div v:shape=3D"_x0000_s30723" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:97.19%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-3.85%'>•</span>Po 8 cyklach wobec b= raku „spadku PSA” oraz </span><span style=3D'position:absolute; top:31.0%;left:9.73%;width:87.82%;height:7.5%'>dobrego samopoczucia pacjent odmówił </span><span style=3D'position:absolute;top:38.0%; left:9.73%;width:84.45%;height:7.5%'>kontynuacji leczenia </span> <div style=3D'position:absolute;top:46.5%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Nie wyraz= ił zgody na hormonoterapię </span></div> <div style=3D'position:absolute;top:55.25%;left:5.99%;width:88.2%;height:7= .5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Nie zgłaszał się do kontroli </span></div> <span style=3D'position:absolute;top:63.75%;left:9.73%;width:100.0%;height= :7.5%'><span class=3DBB style=3D'position:absolute;left:-3.74%'>•</span>Po 9 miesiącach z nasilonymi bólami kostnymi </span><span style=3D'position:absolute;top:70.75%;left:9.73%;width:84.45%;height:7.5%'= >oraz PSA> 1000 zgłosił się do kontroli. </span><span style=3D'position:absolute;top:79.25%;left:9.73%;width:95.69%;height:7.5%'= ><span class=3DBB style=3D'position:absolute;left:-3.91%'>•</span>W badania= ch obrazowych – progresja zmian </span><span style=3D'position:absolute; top:86.5%;left:9.73%;width:84.45%;height:7.5%'>osteosklerotycznych </s= pan> <div style=3D'position:absolute;top:95.0%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span><span style=3D'mso-special-format:lastCR;display:none'> </span></span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0037.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 37.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Pacjent II"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"31"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" 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</span> <div style=3D'position:absolute;top:46.5%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Do chwili= obecnej otrzymał 3 cykle </span></div> <span style=3D'position:absolute;top:55.25%;left:9.73%;width:91.38%;height= :7.5%'><span class=3DBB style=3D'position:absolute;left:-4.09%'>•</span>Spadek po= ziomu PSA z >1000 do 786 i 470 </span><span style=3D'position:absolute;top:62= .25%; left:9.73%;width:84.45%;height:7.5%'>ng/ml </span> <div style=3D'position:absolute;top:70.75%;left:5.99%;width:88.2%;height:7= .5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Tolerancja leczenia dobra.</span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: 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v:shape=3D"_x0000_s33794" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Podsumowanie</div> <div v:shape=3D"_x0000_s33795" class=3DB> <div style=3D'position:absolute;top:24.0%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span> </span></div> <div style=3D'position:absolute;top:32.5%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span> </span></div> <span style=3D'position:absolute;top:41.0%;left:9.73%;width:84.45%;height:= 7.5%'><span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Więk= szość pacjentów<span style=3D'mso-spacerun:yes'> </span>z HRCP to s= tarsi </span><span style=3D'position:absolute;top:48.0%;left:9.73%;width:84.45%;height:7.5%'>= mężczyźni z typowymi dla tego wieku </span><span style=3D'position:absolute;top:55.2= 5%; left:9.73%;width:88.2%;height:7.5%'>współistniejącymi<span style=3D'mso-spacerun:yes'> </span>schorzeniami głównie = </span><span style=3D'position:absolute;top:62.25%;left:9.73%;width:84.45%;height:7.5%'= >układu krążenia </span> <div style=3D'position:absolute;top:70.75%;left:5.99%;width:88.2%;height:7= .5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span><span style=3D'mso-special-format:lastCR;display:none'> </span></span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0056.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 56.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Podsumowanie Docetaxel w HR= PC"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"34"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s34818" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s34819" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s34818" class=3DT><span style=3D'position:absolute; top:2.5%;left:5.99%;width:88.2%;height:10.25%'>Podsumowanie<br> </span><span style=3D'position:absolute;top:12.25%;left:5.99%;width:88.2%; height:10.25%'>Docetaxel w HRPC</span></div> <div v:shape=3D"_x0000_s34819" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:88.76%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.21%'>•</span>Dobra tolerancja lec= zenia pomimo wieku </span><span style=3D'position:absolute;top:31.0%;left:9.73%; width:84.45%;height:7.5%'>pacjentów </span><span style=3D'posit= ion: absolute;top:39.5%;left:9.73%;width:86.32%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.33%'>•</span>Terapia ze stosunkowo niewielką ilością </span><span style=3D'position:absolute; top:46.5%;left:9.73%;width:84.45%;height:7.5%'>istotnych klinicznie działań ubocznych </span><span style=3D'position:absolute; top:55.25%;left:9.73%;width:98.12%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-3.81%'>•</span>Zysk kliniczny u zna= cznego odsetka leczonych </span><span style=3D'position:absolute;top:62.25%;left:= 9.73%; width:91.38%;height:7.5%'>zarówno w czasie do progresji jak i <b>ja= kości </b></span><span style=3D'position:absolute;top:69.25%;left:9.73%;width:84= .45%; height:7.5%'><b>życia. </b></span><span style=3D'position:absolut= e; top:77.75%;left:9.73%;width:98.87%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-3.78%'>•</span>Możliwoś&#= 263; ponownej CHT - korzystna opcja w </span><span style=3D'position:absolute; top:85.0%;left:9.73%;width:84.45%;height:7.5%'>terapii HRPC </span> <div style=3D'position:absolute;top:93.5%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span><span style=3D'mso-special-format:lastCR;display:none'> </span></span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0051.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 51.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: ASCO 2009"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"35"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s35842" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s35843" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s35842" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>ASCO 2009</div> <div v:shape=3D"_x0000_s35843" class=3DB> <div style=3D'text-align:center'><span style=3D'position:absolute;top:24.0= %; left:5.99%;width:88.2%;height:9.25%'><span style=3D'mso-special-format:nob= ullet; display:none;font-family:Arial'>•</span><span style=3D'font-size:125= %'><span style=3D'mso-spacerun:yes'> </span>Standardem w leczeniu= HRPC </span></span><span style=3D'position:absolute;top:32.75%;left:8.05%;width:87.64%;height:9.25%= '><span style=3D'font-size:125%'>pozostaje docetaxel + Prednison </span></span= ></div> <div style=3D'text-align:center;position:absolute;top:43.5%;left:5.99%; width:88.2%;height:9.25%'><span style=3D'mso-special-format:nobullet;displ= ay: none;font-family:Arial'>•</span><span style=3D'font-size:125%;displa= y: none'> </span></div> <div style=3D'text-align:center'><span style=3D'position:absolute;top:54.0= %; left:-.18%;width:100.56%;height:9.25%'><span style=3D'mso-special-format:n= obullet; display:none;font-family:Arial'>•</span><span style=3D'font-size:125= %'>Próby kojarzenia docetaxelu z innymi </span></span><span style=3D'position:absol= ute; top:63.0%;left:9.73%;width:84.45%;height:9.25%'><span style=3D'font-size:1= 25%'>substancjami</span></span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0057.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 57.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Rak prostaty Nowe aspekty ASCO 2009"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script src=3Dscript.js></script><script></script><![endif]><o:shapelayout v:ext=3D"edit"> <o:idmap v:ext=3D"edit" data=3D"36"/> </o:shapelayout> </head> <body lang=3DPL style=3D'margin:0px;background-color:black' onclick=3D"DocumentOnClick()" onresize=3D"_RSW()" onload=3D"LoadSld()" onkeypress=3D"_KPH()"> <div id=3DSlideObj class=3Dsld style=3D'position:absolute;top:0px;left:0px; width:534px;height:400px;font-size:16px;background-color:white;clip:rect(0%= , 101%, 101%, 0%); visibility:hidden'><p:slide coordsize=3D"720,540" colors=3D"#ffffff,#000000,#eeece1,#1f497d,#4f81bd,#c0504d,#0000ff,#800080" masterhref=3D"master03.xml"> <p:shaperange href=3D"master03.xml#_x0000_s1025"/><p:shaperange href=3D"master03.xml#_x0000_m1026"/><v:shape id=3D"_x0000_s36866" type=3D= "#_x0000_m1026" style=3D'position:absolute;left:36pt;top:21.625pt;width:9in;height:90pt; visibility:visible;mso-wrap-style:square;v-text-anchor:middle'> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"title" position=3D"-1"/></v:shape><p:shaperange href=3D"master03.xml#_x0000_m1027"/><v:shape id=3D"_x0000_s36867" type=3D= "#_x0000_m1027" style=3D'position:absolute;left:36pt;top:126pt;width:9in;height:356.375pt; visibility:visible;mso-wrap-style:square;v-text-anchor:top'> <v:fill o:detectmouseclick=3D"t"/> <v:stroke o:forcedash=3D"f"/> <v:path arrowok=3D"t"/> <o:lock v:ext=3D"edit" rotation=3D"f" aspectratio=3D"f" position=3D"f" se= lection=3D"f" verticies=3D"f" text=3D"f" adjusthandles=3D"f" grouping=3D"t" shapetype= =3D"f"/> <v:textbox style=3D'layout-flow:horizontal;mso-rotate-with-shape:t' inset= =3D"7.2pt,3.6pt,7.2pt,3.6pt"/> <p:placeholder type=3D"object" position=3D"-1"/></v:shape> <div v:shape=3D"_x0000_s36866" class=3DT><span style=3D'position:absolute; top:2.5%;left:5.99%;width:88.2%;height:10.25%'>Rak prostaty <br> </span><span style=3D'position:absolute;top:12.25%;left:5.99%;width:88.2%; height:10.25%'>Nowe aspekty ASCO 2009</span></div> <div v:shape=3D"_x0000_s36867" class=3DB> <div style=3D'position:absolute;top:24.0%;left:5.99%;width:88.2%;height:6.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'font-size:88%'><span class=3DBB style=3D'position:absolute;left:-= 4.43%'>•</span></span><span style=3D'font-size:88%'>Wewnątrzguzowa synteza androgenów = </span></span></div> <span style=3D'position:absolute;top:31.5%;left:9.73%;width:93.07%;height:= 6.5%'><span style=3D'font-size:88%'><span class=3DBB style=3D'position:absolute;left:-= 4.02%'>•</span></span><span style=3D'font-size:88%'>Wzmożenie wrażliwości (upregulation) receptora </span></span><span style=3D'position:absolute;top:37.75%;left:9= .73%; width:90.26%;height:6.5%'><span style=3D'font-size:88%'>androgenowego w przerzutowym raku prostaty </span></span><span style=3D'position:abso= lute; top:45.0%;left:5.99%;width:97.94%;height:6.5%'><span style=3D'mso-special-= format: nobullet;display:none;font-family:Arial'>•</span><span style=3D'font= -size: 88%'><span style=3D'mso-spacerun:yes'> </span>Powyższe wyniki uzasadniają dwa bieżące trendy = </span></span><span style=3D'position:absolute;top:51.25%;left:9.73%;width:90.63%;height:6.5%'= ><span style=3D'font-size:88%'>rozwoju leków dla przerzutowego raka gruczołu </span></span><span style=3D'position:absolute;top:57.5%; left:9.73%;width:97.75%;height:6.5%'><span style=3D'font-size:88%'>krokowe= go znajdujące się w fazie badań klinicznych </span></span> <div style=3D'position:absolute;top:65.0%;left:5.99%;width:88.2%;height:6.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'font-size:88%'><span class=3DBB style=3D'position:absolute;left:-= 4.43%'>•</span></span><span style=3D'font-size:88%'>Nowy antyandrogen MDV3100 </span></span></div> <div style=3D'position:absolute;top:72.5%;left:5.99%;width:88.2%;height:6.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'font-size:88%'><span class=3DBB style=3D'position:absolute;left:-= 4.43%'>•</span></span><span style=3D'font-size:88%'>Inhibitor CYP17 -abirateron </span></span></di= v> <div style=3D'position:absolute;top:80.0%;left:5.99%;width:88.2%;height:7.= 5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span style=3D'visibility:hidden'><span class=3DBB style=3D'position:absolute;le= ft:-4.43%'>•</span></span><span style=3D'mso-special-format:lastCR;display:none'> </span></span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0052.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf>  <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\slide00= 52.htm" id=3D"webarch_temp_base_tag"> <![endif]> <meta name=3DDescription content=3D"2009-10-08: Nowe terapie ASCO 2009"> <link rel=3DStylesheet href=3D"master03_stylesheet.css"> <![if !ppt]> <style media=3Dprint>  </style> <script 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v:shape=3D"_x0000_s37890" class=3DT style=3D'position:absolute;top:7.= 25%; left:5.99%;width:88.2%;height:10.25%'>Nowe terapie ASCO 2009</div> <div v:shape=3D"_x0000_s37891" class=3DB><span style=3D'position:absolute; top:24.0%;left:9.73%;width:93.44%;height:7.5%'><span class=3DBB style=3D'position:absolute;left:-4.0%'>•</span>Receptor androgenowy pozostaje istotnym </span><span style=3D'position:absolute;top:31.0%;left:= 9.73%; width:84.45%;height:7.5%'>celem terapeutycznym nawet w HRPC </span><sp= an style=3D'position:absolute;top:39.5%;left:9.73%;width:97.94%;height:7.5%'>= <span class=3DBB style=3D'position:absolute;left:-3.82%'>•</span>MDV3100 j= est obiecującym antyandrogenem </span><span style=3D'position:absolute; top:46.5%;left:9.73%;width:88.01%;height:7.5%'>o mechaniźmie działania odmiennym niż </span><span style=3D'position:absolute; top:53.75%;left:9.73%;width:88.76%;height:7.5%'>bicalutamid, aktywnym w HR= PC zarówno </span><span style=3D'position:absolute;top:60.75%;left:9.7= 3%; width:84.45%;height:7.5%'>przed jak i po chemioetrapii </span> <div style=3D'position:absolute;top:69.25%;left:5.99%;width:88.2%;height:7= .5%'><span style=3D'position:absolute;top:0%;left:4.24%;width:95.75%;height:100.0%'><= span class=3DBB style=3D'position:absolute;left:-4.43%'>•</span>Preparat w trakcie badań klinicznych</span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/slide0053.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-microsoft-com:office:office" xmlns:p=3D"urn:schemas-microsoft-com:office:powerpoint" xmlns:oa=3D"urn:schemas-microsoft-com:office:activation" xmlns=3D"http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId 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style=3D'font-size:94%'>Immunoterapia w leczeniu HRPC nie wykazała </span></span><span style=3D'position:abso= lute; top:28.25%;left:9.73%;width:84.45%;height:7.0%'><span style=3D'font-size:9= 4%'>wpływu na ból, poziomy PSA lub chorobę </span></span><span style=3D'position:absolute;top:33.5%;left:9.73%;width:84.45%;height:7.0%'>= <span style=3D'font-size:94%'>mierzalną </span></span></div> <div class=3DB style=3D'mso-line-spacing:"80 20 0"'><span style=3D'position= :absolute; top:40.25%;left:9.73%;width:87.26%;height:7.0%'><span style=3D'font-size:9= 4%'><span style=3D'mso-special-format:bullet;position:absolute;left:-4.29%;font-fami= ly: Arial'>•</span></span><span style=3D'font-size:94%'>TYM NIEMNIEJ = 211; nieoczekiwanie wykazano </span></span><span style=3D'position:absolute; top:45.5%;left:9.73%;width:95.13%;height:7.0%'><span style=3D'font-size:94= %'>poprawę przeżyć całkowitych w 3 badaniach III </span></span><span style=3D'position:absolute;top:50.75%;left:9.73%;width:84.45%;height:7.0%'= ><span style=3D'font-size:94%'>fazy: </span></span></div> <div class=3DB1 style=3D'mso-line-spacing:"80 20 0";position:absolute;top:= 57.5%; left:11.04%;width:83.14%;height:6.0%'><span style=3D'position:absolute; top:0%;left:3.6%;width:96.17%;height:100.0%'><span style=3D'font-size:93%'= ><span style=3D'mso-special-format:bullet;position:absolute;left:-3.74%;font-fami= ly: Arial'>–</span></span><span style=3D'font-size:93%'><span style=3D'mso-spacerun:yes'> </span>Sipuleucel-T </span></span></= div> <div class=3DB1 style=3D'mso-line-spacing:"80 20 0"'><span style=3D'positi= on:absolute; top:63.25%;left:14.04%;width:86.7%;height:6.0%'><span style=3D'font-size:9= 3%'><span style=3D'mso-special-format:bullet;position:absolute;left:-3.45%;font-fami= ly: Arial'>–</span></span><span style=3D'font-size:93%'>sugerowana jest także przy użyciu PROSTVAC-VF-</span></span><span style=3D'posit= ion: absolute;top:68.0%;left:14.04%;width:79.96%;height:6.0%'><span style=3D'font-size:93%'>Tricom </span></span></div> <div class=3DB style=3D'text-align:center;mso-line-spacing:"80 20 0";posit= ion: absolute;top:73.75%;left:5.99%;width:88.2%;height:7.0%'><span style=3D'mso-special-format:nobullet;display:none;font-family:Arial'>̶= 6;</span><span style=3D'font-size:94%;color:red'>„BYĆ MOŻE IMMUNOTERAPIA DZIAŁA” </span></div> <div class=3DB style=3D'text-align:center;mso-line-spacing:"80 20 0";posit= ion: absolute;top:80.25%;left:5.99%;width:88.2%;height:4.75%'><span style=3D'mso-special-format:nobullet;display:none;font-family:Arial'>̶= 6;</span><span style=3D'font-size:63%'><i>(komentarz prowadzącego sesję)</i></s= pan><span style=3D'font-size:63%;mso-special-format:lastCR;display:none'><i> </i= ></span></div> </div> </p:slide></div> </body> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/master01.htm 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g_scaleInFrame||(IsWin("PPTSld") && parent.IsFullScrMode() ) ) document.body.scroll=3D"no" _RSW() if( IsWin("PPTSld") && parent.IsFullScrMode() ) FullScrInit(); =09 MakeSldVis(); ChkAutoAdv() if( runAnimations ) { if( document.all("NSPlay") ) document.all("NSPlay").autoStart =3D false; if( sld.filters && sld.filters.revealtrans ) setTimeout( "document.body.start()", sld.filters.revealtrans.duration * = 1000 ); else document.body.start(); } } function MakeSldVis() { var fTrans=3Dg_showAnimation && SldHasTrans() if( fTrans ) { if( g_bgSound ) { idx=3Dg_bgSound.indexOf(","); pptSound.src=3Dg_bgSound.substr( 0, idx ); pptSound.loop=3D -(parseInt(g_bgSound.substr(idx+1))); } SlideObj.filters.revealtrans.Apply() } SlideObj.style.visibility=3D"visible" if( fTrans ) SlideObj.filters.revealtrans.Play() } function MakeNotesVis() { if( !IsNts() ) return false SlideObj.style.display=3D"none" nObj =3D document.all.item("NotesObj") parent.SetHasNts(0) if( nObj ) { nObj.style.display=3D"" parent.SetHasNts(1) } return 1 } function ChkAutoAdv() { if(SldHasTrans()) SlideObj.onfilterchange=3DAutoAdv else AutoAdv() } function AutoAdv() { if(!IsWin("PPTSld") || !gUseSldTimings )return var sld=3DGetCurSld() if( (sld.mAdvDelay>0) && !parent.IsFramesMode() ) setTimeout("parent.GoToNextSld()",sld.mAdvDelay) } function GetObj(id) { if(g_supportsPPTHTML) return document.all(id); else return document.getElementById(id); } function SldHasTrans() { return SlideObj.style.filter !=3D ""; } function GetSldId() { return sId=3Dlocation.href.substring(location.href.la= stIndexOf('/')+1) } function HideMenu() { if( frames["PPTSld"] && PPTSld.document.all.item("ctx= tmenu") && PPTSld.ctxtmenu.style.display!=3D"none" ) { PPTSld.ctxtmenu.styl= e.display=3D'none'; return true } return false } function IsWin( name ) { return window.name =3D=3D name } function IsNts() { return IsWin("PPTNts") } function IsSldOrNts() { return( IsWin("PPTSld")||IsWin("PPTNts") ) } function SupportsPPTAnimation() { return( navigator.platform =3D=3D "Win32"= && navigator.appVersion.indexOf("Windows")>0 ) } function SupportsPPTHTML() { var appVer=3Dnavigator.appVersion, msie=3DappVer.indexOf("MSIE "), ver=3D0 if( msie >=3D 0 ) ver=3DparseFloat( appVer.substring( msie+5, appVer.indexOf(";",msie) ) ) else ver=3DparseInt(appVer) return( ver >=3D 4 && msie >=3D 0 ) } function _RSW() { if( !g_supportsPPTHTML || IsNts() || ( !g_scaleInFrame && (!IsWin("PPTSld") || !parent.IsFullScrMode()) ) ) return var padding=3D0; if( IsWin("PPTSld") && parent.IsFramesMode() ) padding=3D6 cltWidth=3Ddocument.body.clientWidth-padding cltHeight=3Ddocument.body.clientHeight-padding factor=3D(1.0*cltWidth)/g_origW if( cltHeight < g_origH*factor ) factor=3D(1.0*cltHeight)/g_origH newSize =3D g_origSz * factor if( newSize < 1 ) newSize=3D1 s=3DSlideObj.style s.fontSize=3DnewSize+"px" s.posWidth=3Dg_origW*factor s.posHeight=3Dg_origH*factor s.posLeft=3D(cltWidth-s.posWidth+padding)/2 s.posTop=3D(cltHeight-s.posHeight+padding)/2 if( g_scaleHyperlinks ) ScaleHyperlinks( factor ) } function _InitAnimations() { animRuntimeInstalled =3D ''+document.body.localTime !=3D 'undefined'; isFullScreen =3D (window.name =3D=3D "PPTSld") && !parent.IsFramesMode(); g_animUseRuntime =3D g_showAnimation && animRuntimeInstalled && !(isFullSc= reen && parent.IsSldVisited()); if( g_animUseRuntime ) { collSeq =3D document.all.tags("seq"); if( collSeq !=3D null ) { for(ii=3D0;ii<collSeq.length;ii++) { if( collSeq[ii].getAttribute( "p:nodeType" ) =3D=3D "mainSeq" ) { g_animMainSequence =3D collSeq[ii]; break; } } } if( g_animItemsToHide && document.body.playAnimations !=3D false ) { for(jj =3D 0; jj < g_animItemsToHide.length; jj++) { if( hideObj =3D GetObj(g_animItemsToHide[jj]) ) hideObj.runtimeStyle.visibility=3D"hidden"; } } if( g_animInteractiveItems ){ for(jj =3D 0; jj < g_animInteractiveItems.length; jj++) { if( triggerObj =3D GetObj(g_animInteractiveItems[jj]) ) triggerObj.runtimeStyle.cursor=3D"hand"; } } if( gUseSldTimings && ''+g_animSlideTime !=3D 'undefined' ) { adjustedTime =3D document.body.calculateAutoAdvanceTimes( g_animSlideTim= e, g_animEffectTimings ); if( IsWin("PPTSld") && adjustedTime !=3D g_animSlideTime ) { var sld =3D GetCurSld(); sld.mAdvDelay =3D adjustedTime * 1000; } } } return g_animUseRuntime; } gSldJump =3D 0, gSldJumpTrack =3D 0, gSldJumpIdx =3D ""; function _KPH() { if( IsNts() ) return; if( !parent.IsFramesMode() && event.keyCode =3D=3D 27 && !HideMenu() ) parent.window.close( self ); else if( event.keyCode =3D=3D 32 ) { if( window.name =3D=3D "PPTSld" ) parent.PPTSld.DocumentOnClick(); else parent.GoToNextSld(); } CatchNumKeys( parent, event ); } function CatchNumKeys( win, event ) { if( win.IsFullScrMode() && (48<=3Devent.keyCode) && (event.keyCode<=3D57) = ) { gSldJump =3D 1; gSldJumpIdx +=3D (event.keyCode-48).toString(); } if( win.IsFullScrMode() && gSldJump && event.keyCode =3D=3D 13 ) { var numSlds =3D parent.GetSldList().mList.length if ( gSldJumpIdx > numSlds ) gSldJumpIdx =3D numSlds; if ( gSldJumpIdx >=3D 0 ) { if ( gSldJumpIdx =3D=3D 0 ) gSldJumpIdx =3D 1; var jumpTo =3D parseInt(gSldJumpIdx); gSldJump =3D 0; gSldJumpIdx =3D ""; win.GoToSld( parent.GetSldList().mList[jumpTo-1].mSldHref ) } } } function _KDH() { if( event.keyCode =3D=3D 8 ) { event.returnValue =3D 0; parent.GoToPrevSld(); } } function DocumentOnClick() { if( IsNts() || parent.HideMenu() ) return; if( ( g_allowAdvOnClick && (window.name=3D=3D"PPTSld") && !parent.IsFrames= Mode() ) || (event && event.keyCode=3D=3D32) ) { if( g_animUseRuntime && g_animMainSequence && g_animMainSequence.cangonex= t ) return; parent.GoToNextSld(); } } var g_supportsPPTHTML =3D SupportsPPTHTML(), g_scaleInFrame =3D 1, gId=3D""= , g_bgSound=3D"", g_scaleHyperlinks =3D false, g_allowAdvOnClick =3D 1, g_showInBrowser = =3D 0, gLoopCont =3D 0, gUseSldTimings =3D 1; var g_showAnimation =3D g_supportsPPTHTML && SupportsPPTAnimation() && ( (w= indow.name=3D=3D"PPTSld" && !parent.IsFramesMode()) || g_showInBrowser );va= r g_animManager =3D null; var g_animUseRuntime =3D false; var g_animItemsToHide, g_animInteractiveItems, g_animSlideTime; var g_animMainSequence =3D null; var ENDSHOW_MESG=3D"Koniec pokazu slajdów, kliknij, aby zakończ= yć.", SCREEN_MODE=3D"Frames", gIsEndShow=3D0, NUM_VIS_SLDS=3D37, SCRIP= T_HREF=3D"script.js", FULLSCR_HREF=3D"fullscreen.htm"; var gCurSld =3D gPrevSld =3D 1, g_offset =3D 0, gNtsOpen =3D gHasNts =3D gO= tlTxtExp =3D 0, gHasNarration =3D 0, gOtlOpen =3D true window.gPPTHTML=3DSupportsPPTHTML() var gMainDoc=3Dnew Array(new hrefList("slide0001.htm",1,-1,1),new hrefList(= "slide0047.htm",1,-1,1),new hrefList("slide0048.htm",1,-1,1),new hrefList("= slide0002.htm",1,-1,1),new hrefList("slide0003.htm",1,-1,1),new hrefList("s= lide0054.htm",1,-1,1),new hrefList("slide0055.htm",1,-1,1),new hrefList("sl= ide0049.htm",1,-1,1),new hrefList("slide0023.htm",1,-1,1),new hrefList("sli= de0020.htm",1,-1,1),new hrefList("slide0025.htm",1,-1,1),new hrefList("slid= e0021.htm",1,-1,1),new hrefList("slide0022.htm",1,-1,1),new hrefList("slide= 0038.htm",1,-1,1),new hrefList("slide0040.htm",1,-1,1),new hrefList("slide0= 041.htm",1,-1,1),new hrefList("slide0026.htm",1,-1,1),new hrefList("slide00= 39.htm",1,-1,1),new hrefList("slide0027.htm",1,-1,1),new hrefList("slide002= 8.htm",1,-1,1),new hrefList("slide0029.htm",1,-1,1),new hrefList("slide0030= .htm",1,-1,1),new hrefList("slide0031.htm",1,-1,1),new hrefList("slide0032.= htm",1,-1,1),new hrefList("slide0045.htm",1,-1,1),new hrefList("slide0033.h= tm",1,-1,1),new hrefList("slide0034.htm",1,-1,1),new hrefList("slide0035.ht= m",1,-1,1),new hrefList("slide0036.htm",1,-1,1),new hrefList("slide0037.htm= ",1,-1,1),new hrefList("slide0046.htm",1,-1,1),new hrefList("slide0024.htm"= ,1,-1,1),new hrefList("slide0056.htm",1,-1,1),new hrefList("slide0051.htm",= 1,-1,1),new hrefList("slide0057.htm",1,-1,1),new hrefList("slide0052.htm",1= ,-1,1),new hrefList("slide0053.htm",1,-1,1)); function FullScrInit() { g_allowAdvOnClick =3D GetCurSld().mAdvOnClk document.body.style.backgroundColor=3D"black" document.oncontextmenu=3Dparent._CM; document.onkeydown =3D _KDH; document.ondragstart=3DCancel document.onselectstart=3DCancel self.focus() } function Redirect( frmId ) { var str=3Ddocument.location.hash,idx=3Dstr.indexOf('#'), sId=3DGetSldId() if(idx>=3D0) str=3Dstr.substr(1); if( window.name !=3D frmId && ( sId !=3D str) ) { obj =3D GetObj("Main-File") window.location.href=3Dobj.href+"#"+sId return 1 } return 0 } var MHTMLPrefix =3D CalculateMHTMLPrefix(); function CalculateMHTMLPrefix() { if ( document.location.protocol =3D=3D 'mhtml:') { href=3Dnew String(document.location.href) Start=3Dhref.indexOf('!')+1 End=3Dhref.lastIndexOf('/')+1 if (End < Start) return href.substring(0, Start) else return href.substring(0, End) } return ''; } function GetTags(base,tag) { if(g_supportsPPTHTML) return base.all.tags(tag); else return base.getElementsByTagName(tag); } function UpdNtsPane(){ if(frames["PPTNts"]) PPTNts.location.replace( MHTMLP= refix+GetHrefObj( gCurSld ).mNtsHref ) } function UpdNavPane( sldIndex ){ if(gNavLoaded) PPTNav.UpdNav() } function UpdOtNavPane(){ if(gOtlNavLoaded) PPTOtlNav.UpdOtlNav() } function UpdOtlPane(){ if(gOtlLoaded) PPTOtl.UpdOtl() } function SetHasNts( fVal ) { if( gHasNts !=3D fVal ) { gHasNts=3DfVal UpdNavPane() } } function ToggleOtlText() { gOtlTxtExp=3D!gOtlTxtExp UpdOtlPane() } function ClearMedia() { if (PPTSld.pptSound) PPTSld.pptSound.loop =3D 0; } function FullScreen() { if ( PPTSld.g_animUseRuntime ) PPTSld.document.body.pause(); ClearMedia(); var href =3D ( document.location.protocol =3D=3D 'mhtml:') ? FULLSCR_HREF = : FULLSCR_HREF+"#"+GetHrefObj(gCurSld).mSldHref; if(PPTNav.event.ctrlKey) { var w =3D (window.screen.availWidth * 1.0) / 2.0 var h =3D w * (PPTSld.g_origH * 1.0) / PPTSld.g_origW win =3D window.open( MHTMLPrefix+href,null,"toolbar=3D0,resizable=3D1,top= =3D0,left=3D0," + "width=3D"+ w + ",height=3D" + h ); if( win.document.body && PPTSld.g_animUseRuntime ) win.document.body.PPTSldFrameset=3Dwindow; } else { win =3D window.open( MHTMLPrefix+href,null,"fullscreen=3Dyes" ); if( win.document.body && PPTSld.g_animUseRuntime ) win.document.body.PPTSldFrameset=3Dwindow; } } function ToggleVNarration() { rObj=3DPPTSld.document.all("NSPlay") if( rObj && !PPTSld.g_animUseRuntime ) { if( (rObj.playState =3D=3D 1)||(rObj.playState =3D=3D 0) ) rObj.Play() else if( rObj.playState =3D=3D 2 ) rObj.Pause() else return; } else if( PPTSld.g_animUseRuntime ) { narObj =3D PPTSld.document.all("narrationID") if( narObj ) narObj.togglePause() } } function GetCurSldNum() { obj=3DGetHrefObj(gCurSld) if( obj.mOrigVis =3D=3D 1 ) return obj.mSldIdx else return gCurSld } function GetNumSlds() { if( GetHrefObj(gCurSld).mOrigVis =3D=3D 1 ) return GetSldList().mNumVisSlds; else return GetSldList().mList.length } function GetSldNum( href ) { for(ii=3D0; ii<GetSldList().mList.length; ii++) { if ( GetSldList().mList[ii].mSldHref =3D=3D href ) return ii+1 } return 1 } function GetHrefObj( sldIdx ){ return GetSldList().mList[sldIdx-1] } function IsFramesMode(){ return ( SCREEN_MODE =3D=3D "Frames" ) } function IsFullScrMode(){ return ( SCREEN_MODE =3D=3D "FullScreen" ) } function GoToNextSld() { ii=3DgCurSld + 1 if( GetHrefObj( ii-1 ).mOrigVis =3D=3D 0 ) { if( ii<=3DGetSldList().mList.length ) { obj=3DGetHrefObj(ii) obj.mVis=3D1 GoToSldNum(ii) return } } else { obj=3DGetHrefObj( ii ) while ( obj && ( obj.mOrigVis =3D=3D 0 ) ) obj=3DGetHrefObj(++ii) if( obj && obj.mOrigVis ) { GoToSldNum(ii) return } } if( gSldStack.length > 1 ) PopSldList(); else if( !IsFramesMode() ) { if( gLoopCont ) GoToFirst() else EndShow() } } function GoToPrevSld() { ii=3DgCurSld-1 if( ii > 0 ) { obj=3DGetHrefObj(ii) while ( obj && ( obj.mVis =3D=3D 0 ) && ( ii>0 ) ) obj=3DGetHrefObj(--ii) if( ii =3D=3D 0 ) ii=3D1 GoToSldNum(ii) } } function GoToFirst(){ GoToSld( GetHrefObj(1).mSldHref ) } function GoToLast() { ii=3DGetSldList().mList.length if( ii !=3D gCurSld ) GoToSld( GetHrefObj(ii).mSldHref ) } function GoToSldNum( num ) { if( PPTSld.event ) PPTSld.event.cancelBubble=3Dtrue obj =3D GetHrefObj( num ) obj.mVis=3D1 gPrevSld=3DgCurSld gCurSld =3D num; PPTSld.location.replace(MHTMLPrefix+obj.mSldHref) if( IsFramesMode() ) { UpdNavPane(); UpdOtlPane(); UpdNtsPane() } } function GoToSld( href ) { if( PPTSld.event ) PPTSld.event.cancelBubble=3Dtrue GetHrefObj( GetSldNum(href) ).mVis=3D1 PPTSld.location.replace(MHTMLPrefix+href) } function SldUpdated( id ) { if( id =3D=3D GetHrefObj(gCurSld).mSldHref ) return gPrevSld=3DgCurSld gCurSld=3DGetSldNum(id) if( IsFramesMode() ) { UpdNavPane(); UpdOtlPane(); UpdNtsPane() } } function PrevSldViewed(){ GoToSld( GetHrefObj(gPrevSld).mSldHref ) } function HasPrevSld() { return ( gIsEndShow || ( gCurSld !=3D 1 && GetHrefO= bj( gCurSld-1 ).mVis =3D=3D 1 )||( GetCurSldNum() > 1 ) ) } function HasNextSld() { return (GetCurSldNum() !=3D GetNumSlds()) } function CloseWindow() { if( HideMenu() ) return; var event =3D PPTSld.event; if( !IsFramesMode() && event && (event.keyCode=3D=3D27 || event.keyCode=3D= =3D32 || event.type=3D=3D"click" ) ) window.close( self ); CatchNumKeys( self, event ); } function Unload() { gIsEndShow=3D0; } function SetupEndShow() { gIsEndShow=3D1; PPTSld.document.body.scroll=3D"no"; PPTSld.document.onkeypress=3DCloseWindow; PPTSld.document.onclick=3DCloseWindow; PPTSld.document.oncontextmenu=3D_CM; } function EndShow() { if( IsFramesMode() ) return if( PPTSld.event ) PPTSld.event.cancelBubble=3Dtrue doc=3DPPTSld.document var dir =3D doc.body.dir if( dir !=3D "rtl" ) dir =3D "ltr"; doc.open() doc.writeln('<html><body dir=3D' + dir + ' bgcolor=3Dblack onload=3Dparent= .SetupEndShow() onunload=3Dparent.Unload()><center><p><font face=3DTahoma c= olor=3Dwhite size=3D2><br><b>' + ENDSHOW_MESG + '</b></font></p></center></= body></html>') doc.close() } function SetSldVisited(){ GetSldList().mList[gCurSld-1].mVisited=3Dtrue } function IsSldVisited(){ return GetSldList().mList[gCurSld-1].mVisited } function hrefList( sldHref, visible, advDelay, advClk ) { this.mSldHref=3D this.mNtsHref =3D sldHref this.mOrigVis=3D this.mVis =3D visible this.mVisited=3D false this.mAdvDelay=3D advDelay this.mAdvOnClk=3D advClk } function SldList(arr,curSld,fEnd) { this.mCurSld =3D curSld; this.mList =3D new Array(); var idx =3D 1; for(ii=3D0;ii<arr.length;ii++) { this.mList[ii] =3D new hrefList( arr[ii].mSldHref, arr[ii].mOrigVis, arr[= ii].mAdvDelay, arr[ii].mAdvOnClk ); if( arr[ii].mOrigVis ) this.mList[ii].mSldIdx =3D idx++; } this.mNumVisSlds =3D idx-1; this.fEndShow =3D fEnd; } function GetSldList() { return gSldStack[gSldStack.length-1] } function GetCurSld() { return parent.GetSldList().mList[parent.gCurSld - 1]= } gSldStack =3D new Array(); gSldStack[0] =3D new SldList(gMainDoc,gCurSld,1) function ToggleOtlPane() { frmset=3Ddocument.all("PPTHorizAdjust") frm=3Ddocument.all("PPTOtl") if( gOtlOpen ) frmset.cols=3D"*,100%" else frmset.cols=3D"25%,*" gOtlOpen=3D!gOtlOpen frm.noResize=3D!frm.noResize UpdOtNavPane() } function ToggleNtsPane() { frmset=3Ddocument.all("PPTVertAdjust") frm=3Ddocument.all("PPTNts") if( gNtsOpen ) frmset.rows=3D"100%,*" else frmset.rows=3D"*,20%" gNtsOpen=3D!gNtsOpen UpdNtsPane() } function ViewCustomShow(idx,fEnd) { if( !IsFullScrMode() ) return; var sldList =3D new Array(); var custShow =3D custShowList[idx-1]; var jj =3D 0; for( ii=3D0;ii<custShow.length;ii++ ) { if( custShow[ii] <=3D gMainDoc.length ) sldList[jj++] =3D gMainDoc[custShow[ii]-1]; } if (sldList.length > 0) { PushSldList(sldList,fEnd); gCurSld =3D 1; } else if( PPTSld.event ) PPTSld.event.cancelBubble=3Dtrue } function PushSldList(arr,fEnd) { var ii =3D gSldStack.length; gSldStack[ii] =3D new SldList(arr,gCurSld,fEnd); GoToSld( gSldStack[ii].mList[0].mSldHref ); } function PopSldList() { if (gSldStack[gSldStack.length-1].fEndShow) EndShow() else { gCurSld =3D gSldStack[gSldStack.length-1].mCurSld; gSldStack[gSldStack.length-1] =3D null; gSldStack.length--; var sldList =3D gSldStack[gSldStack.length-1]; GoToSld( sldList.mList[gCurSld - 1].mSldHref ); } } var custShowList=3Dnew Array(); function ImgBtn( oId,bId,w,action ) { var t=3Dthis t.Perform =3D _IBP t.SetActive =3D _IBSetA t.SetInactive=3D _IBSetI t.SetPressed =3D _IBSetP t.SetDisabled=3D _IBSetD t.Enabled =3D _IBSetE t.ChangeIcon =3D null t.UserAction =3D action t.ChgState =3D _IBUI t.mObjId =3D oId t.mBorderId=3D bId t.mWidth =3D w t.mIsOn =3D t.mCurState =3D 0 } function _IBSetA() { if( this.mIsOn ) { obj=3Dthis.ChgState( gHiliteClr,gShadowClr,2 ) obj.style.posTop=3D0 } } function _IBSetI() { if( this.mIsOn ) { obj=3Dthis.ChgState( gFaceClr,gFaceClr,1 ) obj.style.posTop=3D0 } } function _IBSetP() { if( this.mIsOn ) { obj=3Dthis.ChgState( gShadowClr,gHiliteClr,2 ) obj.style.posLeft+=3D1; obj.style.posTop+=3D1 } } function _IBSetD() { obj=3Dthis.ChgState( gFaceClr,gFaceClr,0 ) obj.style.posTop=3D0 } function _IBSetE( state ) { var t=3Dthis GetObj( t.mBorderId ).style.visibility=3D"visible" if( state !=3D t.mIsOn ) { t.mIsOn=3Dstate if( state ) t.SetInactive() else t.SetDisabled() } } function _IBP() { var t=3Dthis if( t.mIsOn ) { if( t.UserAction !=3D null ) t.UserAction() if( t.ChangeIcon ) { obj=3DGetObj(t.mObjId) if( t.ChangeIcon() ) obj.style.posLeft=3Dobj.style.posLeft+(t.mCurState-4)*t.mWidth else obj.style.posLeft=3Dobj.style.posLeft+(t.mCurState-0)*t.mWidth } t.SetActive() } } function _IBUI( clr1,clr2,nextState ) { var t=3Dthis SetBorder( GetObj( t.mBorderId ),clr1,clr2 ) obj=3DGetObj( t.mObjId ) obj.style.posLeft=3Dobj.style.posLeft+(t.mCurState-nextState)*t.mWidth-obj= .style.posTop t.mCurState=3DnextState return obj } function TxtBtn( oId,oeId,action,chkState ) { var t=3Dthis t.Perform =3D _TBP t.SetActive =3D _TBSetA t.SetInactive=3D _TBSetI t.SetPressed =3D _TBSetP t.SetDisabled=3D _TBSetD t.SetEnabled =3D _TBSetE t.GetState =3D chkState t.UserAction =3D action t.ChgState =3D _TBUI t.mObjId =3D oId t.m_elementsId=3D oeId t.mIsOn =3D 1 } function _TBSetA() { var t=3Dthis if( t.mIsOn && !t.GetState() ) t.ChgState( gHiliteClr,gShadowClr,0,0 ) } function _TBSetI() { var t=3Dthis if( t.mIsOn && !t.GetState() ) t.ChgState( gFaceClr,gFaceClr,0,0 ) } function _TBSetP() { if( this.mIsOn ) this.ChgState( gShadowClr,gHiliteClr,1,1 ) } function _TBSetD() { this.ChgState( gFaceClr,gFaceClr,0,0 ) this.mIsOn =3D 0 } function _TBSetE() { var t=3Dthis if( !t.GetState() ) t.ChgState( gFaceClr,gFaceClr,0,0 ) else t.ChgState( gShadowClr,gHiliteClr,1,1 ) t.mIsOn =3D 1 } function _TBP() { var t=3Dthis if( t.mIsOn ) { if( t.UserAction !=3D null ) t.UserAction() if( !t.GetState ) return if( t.GetState() ) t.SetPressed() else t.SetActive() } } function _TBUI( clr1,clr2,lOffset,tOffset ) { SetBorder( GetObj( this.mObjId ),clr1,clr2 ) Offset( GetObj( this.m_elementsId ),lOffset,tOffset ) } function Offset( obj, top, left ){ obj.style.top=3Dtop; obj.style.left=3Dle= ft } function SetBorder( obj, upperLeft, lowerRight ) { s=3Dobj.style; s.borderStyle =3D "solid" s.borderWidth =3D 1 s.borderLeftColor =3D s.borderTopColor =3D upperLeft s.borderBottomColor=3D s.borderRightColor =3D lowerRight } function GetBtnObj(){ return gBtnArr[window.event.srcElement.id] } function BtnOnOver(){ b=3DGetBtnObj(); if( b !=3D null ) b.SetActive() } function BtnOnDown(){ b=3DGetBtnObj(); if( b !=3D null ) b.SetPressed() } function BtnOnOut(){ b=3DGetBtnObj(); if( b !=3D null ) b.SetInactive() } function BtnOnUp() { b=3DGetBtnObj() if( b !=3D null ) b.Perform() else Upd() } function GetNtsState(){ return parent.gNtsOpen } function GetOtlState(){ return parent.gOtlOpen } function GetOtlTxtState(){ return parent.gOtlTxtExp } function NtsBtnSetFlag( fVal ) { s=3Ddocument.all.item( this.m_flagId ).style s.display=3D"none" if( fVal ) s.display=3D"" else s.display=3D"none" } function _BSetA_Border(){ b =3D gBtnArr[this.mObjId]; if( b !=3D null ) b.S= etActive() } function _BSetI_Border(){ b =3D gBtnArr[this.mObjId]; if( b !=3D null ) b.S= etInactive() } function _BSetP_Border(){ b =3D gBtnArr[this.mObjId]; if( b !=3D null ) b.S= etPressed() } function _BSetA_BorderImg() { b =3D gBtnArr[this.mBorderId] if( b !=3D null && this.mIsOn && !b.GetState() ) { obj=3Dthis.ChgState( gHiliteClr,gShadowClr,2 ) obj.style.posTop=3D0 } } function _BSetI_BorderImg() { b =3D gBtnArr[this.mBorderId] if( b !=3D null && this.mIsOn && !b.GetState() ) { obj=3Dthis.ChgState( gFaceClr,gFaceClr,1 ) obj.style.posTop=3D0 } } var gHiliteClr=3D"THREEDHIGHLIGHT",gShadowClr=3D"THREEDSHADOW",gFaceClr=3D"= THREEDFACE" var gBtnArr =3D new Array() gBtnArr["nb_otl"] =3D new TxtBtn( "nb_otl","nb_otlElem",parent.ToggleOtlPan= e,GetOtlState ) gBtnArr["nb_otlElem"] =3D new TxtBtn( "nb_otl","nb_otlElem",parent.ToggleOt= lPane,GetOtlState ) gBtnArr["nb_nts"] =3D new ImgBtn( "nb_nts","nb_ntsBorder",10,parent.ToggleN= tsPane ) gBtnArr["nb_nts"].SetActive =3D _BSetA_BorderImg; gBtnArr["nb_nts"].SetInactive =3D _BSetI_BorderImg; gBtnArr["nb_ntsBorder"] =3D new TxtBtn( "nb_ntsBorder","nb_ntsElem",parent.= ToggleNtsPane,GetNtsState ) gBtnArr["nb_ntsElem"] =3D new TxtBtn( "nb_ntsBorder","nb_ntsElem",parent.To= ggleNtsPane,GetNtsState ) gBtnArr["nb_prevBorder"] =3D gBtnArr["nb_prev"]=3D new ImgBtn( "nb_prev","n= b_prevBorder",30,parent.GoToPrevSld ) gBtnArr["nb_nextBorder"] =3D gBtnArr["nb_next"]=3D new ImgBtn( "nb_next","n= b_nextBorder",30,parent.GoToNextSld ) gBtnArr["nb_sldshw"]=3D new ImgBtn( "nb_sldshw","nb_sldshwBorder",18,parent= .FullScreen ) gBtnArr["nb_sldshwBorder"] =3D new TxtBtn( "nb_sldshw","nb_sldshwBorder",pa= rent.FullScreen,null ) gBtnArr["nb_sldshwBorder"].SetActive =3D _BSetA_Border; gBtnArr["nb_sldshwBorder"].SetInactive =3D _BSetI_Border; gBtnArr["nb_sldshwText"] =3D new TxtBtn( "nb_sldshw","nb_sldshwText",parent= .FullScreen,null ) gBtnArr["nb_sldshwText"].SetActive =3D _BSetA_Border; gBtnArr["nb_sldshwText"].SetInactive =3D _BSetI_Border; gBtnArr["nb_voice"] =3D gBtnArr["nb_voiceBorder"] =3D new ImgBtn( "nb_voice= ","nb_voiceBorder",18,parent.ToggleVNarration ) gBtnArr["nb_otlTxtBorder"] =3D gBtnArr["nb_otlTxt"]=3D new ImgBtn( "nb_otlT= xt","nb_otlTxtBorder",23,parent.ToggleOtlText ) gBtnArr["nb_ntsBorder"].m_flagId=3D "nb_nts" gBtnArr["nb_ntsBorder"].SetFlag =3D NtsBtnSetFlag gBtnArr["nb_otlTxt"].ChangeIcon=3D GetOtlTxtState var sNext=3D"Dalej",sPrev=3D"Poprzedni",sEnd=3D"Zakończ pokaz",sFont= =3D"Arial",sArrow=3D"Strzałka",sFreeform=3D"Dowolny kształt",sRec= t=3D"Prostokąt",sOval=3D"Owal" function ShowMenu() { BuildMenu(); var doc=3DPPTSld.document.body,x=3DPPTSld.event.clientX+doc.scrollLeft,y= =3DPPTSld.event.clientY+doc.scrollTop m =3D PPTSld.document.all.item("ctxtmenu") m.style.pixelLeft=3Dx if( (x+m.scrollWidth > doc.clientWidth)&&(x-m.scrollWidth > 0) ) m.style.pixelLeft=3Dx-m.scrollWidth m.style.pixelTop=3Dy if( (y+m.scrollHeight > doc.clientHeight)&&(y-m.scrollHeight > 0) ) m.style.pixelTop=3Dy-m.scrollHeight m.style.display=3D"" } function _CM() { if( !parent.IsFullScrMode() ) return; if(!PPTSld.event.ctrlKey) { ShowMenu() return false } else HideMenu() } function BuildMenu() { if( PPTSld.document.all.item("ctxtmenu") ) return var mObj=3DCreateItem( PPTSld.document.body ) mObj.id=3D"ctxtmenu" mObj.style.visibility=3D"hidden" var s=3DmObj.style s.position=3D"absolute" s.cursor=3D"default" s.width=3D"120px" SetCMBorder(mObj,"menu","black") var iObj=3DCreateItem( mObj ) SetCMBorder( iObj, "threedhighlight","threedshadow" ) iObj.style.padding=3D2 CreateMenuItem( iObj,sNext,M_GoNextSld,M_True ) CreateMenuItem( iObj,sPrev,M_GoPrevSld,M_HasPrevSld ) CreateSeparator( iObj ) CreateMenuItem( iObj,sEnd,M_End,M_True ) mObj.style.visibility=3D"visible" } function Cancel() { window.event.cancelBubble=3Dtrue; window.event.returnVa= lue=3Dfalse } function Highlight() { ChangeClr("activecaption","threedhighlight") } function Deselect() { ChangeClr("threedface","menutext") } function Perform() { e=3DPPTSld.event.srcElement if( e.type=3D=3D"menuitem" && e.IsActive() ) e.Action() else PPTSld.event.cancelBubble=3Dtrue } function ChangeClr( bg,clr ) { e=3DPPTSld.event.srcElement if( e.type=3D=3D"menuitem" && e.IsActive() ) { e.style.backgroundColor=3Dbg e.style.color=3Dclr } } function M_HasPrevSld() { return( parent.HasPrevSld() ) } function M_GoNextSld() { if( gIsEndShow ) M_End(); else GoToNextSld() } function M_GoPrevSld() { if( gIsEndShow ) { gIsEndShow=3D0; history.back();= PPTSld.event.cancelBubble=3Dtrue; } else GoToPrevSld() } function M_True() { return true } function M_End() { window.close( self ) } function CreateMenuItem( node,text,action,eval ) { var e=3DCreateItem( node ) e.type=3D"menuitem" e.Action=3Daction e.IsActive=3Deval e.innerHTML=3Dtext if( !e.IsActive() ) e.style.color=3D"threedshadow" e.onclick=3DPerform e.onmouseover=3DHighlight e.onmouseout=3DDeselect s=3De.style; s.fontFamily=3DsFont s.fontSize=3D"9pt" s.paddingLeft=3D2 } function CreateSeparator( node ) { var sObj=3DCreateItem( node ) SetCMBorder(sObj,"menu","menu") var s=3DsObj.style s.borderTopColor=3D"threedshadow" s.borderBottomColor=3D"threedhighlight" s.height=3D1 s.fontSize=3D"0px" } function CreateItem( node ) { var elem=3DPPTSld.document.createElement("DIV") node.insertBefore( elem ) return elem } function SetCMBorder( o,ltClr,rbClr ) { var s=3Do.style s.backgroundColor=3D"menu" s.borderStyle=3D"solid" s.borderWidth=3D1 s.borderColor=3DltClr+" "+rbClr+" "+rbClr+" "+ltClr } ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/fullscreen.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; 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charset="us-ascii" <html> <head> <meta http-equiv=3DContent-Type content=3D"text/html; charset=3Dus-ascii"> <meta name=3DProgId content=3DPowerPoint.Slide> <meta name=3DGenerator content=3D"Microsoft PowerPoint 12"> <link id=3DMain-File rel=3DMain-File href=3D"../OptymalnyprofilchoregozHRCP= .htm"> <link rel=3DPreview href=3Dpreview.wmf> <title>Optymalny profil chorego z HRCP do leczenia chemioterapią</titl= e> <![if IE]> <base href=3D"file:///C:\367550B0\OptymalnyprofilchoregozHRCP_pliki\frame.h= tm" id=3D"webarch_temp_base_tag"> <![endif]><![if !ppt]><script src=3Dscript.js></script><script>  </script>  <![endif]> </head> <frameset rows=3D"*,25" border=3D0> <frameset cols=3D"25%,*" onload=3D"Load()" id=3DPPTHorizAdjust framespacin= g=3D1 frameborder=3D1> <frame src=3Doutline.htm title=3D"Konspekt" name=3DPPTOtl> <frame src=3Dslide0001.htm title=3D"Slajd" name=3DPPTSld> </frameset> <frameset cols=3D"25%,*" framespacing=3D1> <frame src=3Doutline.htm title=3D"Pasek nawigacyjny konspektu" name=3DPPTOtlNav scrolling=3Dno noresize> <frame src=3Doutline.htm title=3D"Pasek nawigacyjny slajdu" name=3DPPTNav scrolling=3Dno noresize> </frameset> </frameset> </html> ------=_NextPart_01CA4839.6400CBF0 Content-Location: file:///C:/367550B0/OptymalnyprofilchoregozHRCP_pliki/outline.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; 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font-family:Arial;color:buttontext;font-size:9pt; cursor:default'> <img src=3D"notes_flag.gif" id=3D"nb_nts" style=3D'display:none'> No= tatki</div> <div id=3D"nb_ntsBorder" title =3D"Pokaż/Ukryj notatki" onfocus=3D"BtnOnOver()" onblur=3D"BtnOnOut()" TABINDEX=3D1 style= =3D'position:absolute;top:0%;left:0%;width:100%;height:20px'> </div> </td> </table> <table style=3D'position:relative;width:70px' align=3Dright cellpadding=3D0= cellspacing=3D0> <td nowrap> <div id=3D"nb_sldshwText" title=3D"Pokaz slajdów na pełnym ekr= anie" align=3Dcenter style=3D'position:relative;margin-left:20px;padding:3p= x; font-family:Arial;color:buttontext;font-size:9pt;cursor:default'>Pokaz slajdów</div> <div id=3D"nb_sldshwBorder" title=3D"Pokaz slajdów na pełnym ekranie" onfocus=3D"BtnOnOver()" onblur=3D"BtnOnOut()" TABINDEX= =3D5 style=3D'position:absolute;top:0%;left:0%;width:100%;height:20px'> <div style=3D'position:absolute;clip:rect(0px, 18px, 18px, 0px)'><img src=3D"buttons.gif" id=3D"nb_sldshw" style=3D'position:relative;left:-254p= x'></div> </div> </td> <td> <div id=3D"nb_voiceBorder" style=3D'display:none;position:absolute;top:0;l= eft:-40px; width:20px;height:20px' onfocus=3D"BtnOnOver()" onblur=3D"BtnOnOut()" TABI= NDEX=3D4 class=3Dbutton> <div style=3D'position:absolute;clip:rect(0px, 18px, 18px, 0px)'><img src=3D"buttons.gif" id=3D"nb_voice" title=3D"Wstrzymaj/Odtwarzaj narracj&#= 281;" style=3D'position: relative;left:-290px'></div> </div> </td> </table> <table style=3D'position:relative' align=3Dcenter cellpadding=3D0 cellspaci= ng=3D0> <td nowrap> <div id=3D"nb_prevBorder" onfocus=3D"BtnOnOver()" onblur=3D"BtnOnOut()" TA= BINDEX=3D2 class=3Dbutton style=3D'left:-30px'> <div style=3D'position:absolute;clip:rect(0px, 30px, 18px, 0px)'><img src=3D"buttons.gif" id=3D"nb_prev" title=3D"Poprzedni slajd" style=3D'posi= tion:relative; left:0px'></div> </div> <span id=3D"nav_text" style=3D'position:relative;top:3px;width:100px;font-= family: Arial;color:buttontext;font-size:9pt'></span> <div id=3D"nb_nextBorder" onfocus=3D"BtnOnOver()" onblur=3D"BtnOnOut()" TA= BINDEX=3D3 class=3Dbutton> <div style=3D'position:absolute;clip:rect(0px, 30px, 18px, 0px)'><img src=3D"buttons.gif" id=3D"nb_next" title=3D"Następny slajd" style=3D'= position:relative; left:-90px'></div> </div> </td> </table> </div> <div id=3DOtlNavObj onload=3D"Load()" onmouseover=3D"BtnOnOver()" onmousedown=3D"BtnOnDown()" onmouseout=3D"BtnOnOut()" onmouseup=3D"BtnOnUp(= )" onkeypress=3D"ExecBtn()" style=3D'display:none;visibility:hidden'> <table style=3D'position:relative;width:70px' align=3Dleft cellpadding=3D0 = cellspacing=3D0> <td nowrap><div title=3D"Pokaż/Ukryj konspekt" id=3D"nb_otl" onfocus=3D"BtnOnOver()" onblur=3D"BtnOnOut()" TABIN= DEX=3D11 style=3D'position:absolute;top:0%;left:0%;width:100%;height:100%;cursor:de= fault'> <div id=3D"nb_otlElem" align=3Dcenter style=3D'position:relative;padding:3= px;font-family:Arial; color:buttontext;font-size:9pt'>Konspekt</div></div> </td> </table> <table style=3D'position:relative' align=3Dcenter cellpadding=3D0 cellspaci= ng=3D0> <td> <div style=3D'position:absolute;left:-18px;width:24px;height:20px;border-s= tyle: solid;border-width:1px;border-color:threedface' onfocus=3D"BtnOnOver()" on= blur=3D"BtnOnOut()" TABINDEX=3D12 id=3D"nb_otlTxtBorder"> <div style=3D'position:absolute;clip:rect(0px, 22px, 18px, 0px)'><img src=3Dbuttons.gif id=3D"nb_otlTxt" title=3D"Rozwiń/Zwiń konspekt" style=3D'position:relative;left:-157px'></div> </div> </td> </table> </div> <div id=3DOtlObj style=3D'display:none;visibility:hidden;'> <table width=3D"100%" style=3D'font-family:Arial;font-size:9pt'> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>1</font></div> </td> <td width=3D"100%"> <div id=3DPPTP1 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0001.htm');" id=3DPPTL1>Optymalny profil= chorego z HRPC<br> do leczenia chemioterapią</a></font></div> <div id=3DPPTC1 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Wojciech Poborski</li> <li>Oddział Onkologii</li> <li>Szpitala im St. Leszczyńskiego</li> <li>Katowice</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>2</font></div> </td> <td> <div id=3DPPTP2 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0047.htm');" id=3DPPTL2>Zarejestrowane zachorowania na raka prostaty w grupach wiekowych 5 lat w <br> woj. śląskim (2005)</a></font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>3</font></div> </td> <td> <div id=3DPPTP3 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0048.htm');" id=3DPPTL3>Współ= ;czynniki zachorowań na raka prostaty w grupach wiekowych 5 letnich <br> w woj. śląskim (2005)</a></font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>4</font></div> </td> <td> <div id=3DPPTP4 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0002.htm');" id=3DPPTL4>HRPC</a></font><= /div> <div id=3DPPTC4 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Rak gruczołu krokowego rozpoznawany jest zazwyczaj w grupie pacjentów powyżej 60 roku życia.</li> <li>Do powstania hormonooporności dochodzi zazwyczaj po kilku latach leczenia (mediana 18-24 m-cy)</li> <li>Po powstaniu hormonooporności rokowanie jest niekorzystne; czas przeżycia wynosił 9-12 m-cy</li> <li>Petrylak DP. Chemotherapy for the treatment .. w Prostate and renal cancer…. Parthenon Publishing Group 2002</li> <br> <br> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>5</font></div> </td> <td> <div id=3DPPTP5 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0003.htm');" id=3DPPTL5>HRCP</a></font><= /div> <div id=3DPPTC5 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li><span style=3D'mso-spacerun:yes'> </span>Progresja choroby w trakcie hormonoterapii u pacjenta z udokumentowanym rozpoznaniem raka gruczołu krokowego<span style=3D'mso-spacerun:yes'> </span>po wykorzystaniu co najmnie= j II rzutów leczenia</li> <li>I rzut –blokada analogiem GNRH (tzw. pełna blokada nie da= je zysku klinicznego, a tylko większą ilość działań ubocznych)</li> <li>II rzut – antyandrogeny (steroidowe lub niesteroidowe)</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>6</font></div> </td> <td> <div id=3DPPTP6 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0054.htm');" id=3DPPTL6>HRCP</a></font><= /div> <div id=3DPPTC6 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Wskazania do rozpoczęcia terapii:</li> <li>Progresja kliniczna</li> <li>Narastanie poziomu PSA</li> <li>Kastracyjny poziom testosteronu</li> <br> <br> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>7</font></div> </td> <td> <div id=3DPPTP7 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0055.htm');" id=3DPPTL7>Progresja w trak= cie leczenia HRCP</a></font></div> <div id=3DPPTC7 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Obecnie brak standardów postępowania po progresji<span style=3D'mso-spacerun:yes'> </span>po CHT w HRPC</li> <li>Możliwość ponownego zastosowania hormonoterapii</li> <li>Powtórna CHT</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>8</font></div> </td> <td> <div id=3DPPTP8 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0049.htm');" id=3DPPTL8>HRCP</a></font><= /div> <div id=3DPPTC8 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Pacjent z HRPC typowo jest pacjentem starszym, często z licznymi chorobami współistniejącymi.</li> <li>Odpowiedzi terapeutyczne (RR) na klasyczną chemioterapię jedną substancją<span style=3D'mso-spacerun:yes'> </= span>w serii badań wynosiły 8,7%, a mediana przeżycia 9-12 m= -cy*</li> <br> <br> <br> <li>Yagoda A, Petrylak D Cancer 1993;71:1098-109</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>9</font></div> </td> <td> <div id=3DPPTP9 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0023.htm');" id=3DPPTL9>"Doświ= adczenia własne"</a></font></div> <div id=3DPPTC9 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <br> <br> <li>Doświadczenia własne</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>10</font></div> </td> <td> <div id=3DPPTP10 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0020.htm');" id=3DPPTL10>"Do Oś= ;rodka skierowano łącznie 23..."</a></font></div> <div id=3DPPTC10 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li><span style=3D'mso-spacerun:yes'> </span>Do Oś= ;rodka skierowano łącznie 23 chorych spełniających kryt= eria HRPC</li> <li>Do leczenia<span style=3D'mso-spacerun:yes'> </span>chemioterapią<span style=3D'mso-spacerun:yes'> </s= pan>I rzutu zakwalifikowano:</li> <li>21 chorych</li> <li>Wiek 49 do 81 lat</li> <li>Podana ilość cykli 2 do 10 (średnio 5,6), łącznie 117 podań</li> <br> <br> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>11</font></div> </td> <td> <div id=3DPPTP11 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0025.htm');" id=3DPPTL11>Choroby współistniejące<br> istotne klinicznie</a></font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>12</font></div> </td> <td> <div id=3DPPTP12 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0021.htm');" id=3DPPTL12>Tolerancja lecz= enia</a></font></div> <div id=3DPPTC12 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>U 1 pacjenta leukopenia i trombocytopenia WHO III/IV (wiek 81 lat, pomimo zredukowania dawki)</li> <li>Przy 37 cyklach leukopenie ustępujące po odroczeniu cyklu = (o tydzień)</li> <li>Pozostałe objawy uboczne<span style=3D'mso-spacerun:yes'> </span>istotne klinicznie w nasileniu WHO<II</li> <br> <br> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>13</font></div> </td> <td> <div id=3DPPTP13 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0022.htm');" id=3DPPTL13>Odpowiedzi klin= iczne</a></font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>14</font></div> </td> <td> <div id=3DPPTP14 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0038.htm');" id=3DPPTL14>"Prezentac= ja przypadków"</a></font></div> <div id=3DPPTC14 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <br> <li>Prezentacja przypadków</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>15</font></div> </td> <td> <div id=3DPPTP15 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0040.htm');" id=3DPPTL15>Wywiad</a></fon= t></div> <div id=3DPPTC15 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Rozpoznanie ustalono w wieku 67 lat</li> <li>PSA 27 ng/ml, bez cech rozsiewu<span style=3D'mso-spacerun:yes'>&nbs= p; </span>w badaniach obrazowych.</li> <li><span style=3D'mso-spacerun:yes'> </span>Operowany= z założeniem leczenia radykalnego</li> <li>Histologicznie stopień złośliwości Gleason 8, naciekanie torebki stercza</li> <li>Po operacji spadek wartości PSA do 2ng/ml</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>16</font></div> </td> <td> <div id=3DPPTP16 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0041.htm');" id=3DPPTL16>Wywiad c.d.</a>= </font></div> <div id=3DPPTC16 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>W 6 miesięcy po operacji – narastanie poziomu PSA, w CT stwierdzono powiększenie węzłów chłonnych miednicy małej oraz ogniska osteosklerotyczne w kościach miednicy, klinicznie obrzęk kończyny dolnej (ucisk na naczynia)</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>17</font></div> </td> <td> <div id=3DPPTP17 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0026.htm');" id=3DPPTL17>Leczenie</a></f= ont></div> <div id=3DPPTC17 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Włączono pełną blokadę hormonalną (ana= log GN-RH oraz flutamid, a następnie bicalutamid), oraz w zwią= zku z objawami uciskowymi<span style=3D'mso-spacerun:yes'> </span>paliatywną RT</li> <li>Uzyskano ustąpienie dolegliwości klinicznych oraz spadek poziomu PSA < 4ng/ml</li> <li>Po 28 miesiącach leczenia bóle kostne, narastanie<span style=3D'mso-spacerun:yes'> </span>poziomu PSA, zmiany osteoli= tyczno – osteosklerotyczne w kościach miednicy i kręgosłupa.</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>18</font></div> </td> <td> <div id=3DPPTP18 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0039.htm');" id=3DPPTL18>Stwierdzenie HR= PC</a></font></div> <div id=3DPPTC18 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>70 letni pracownik umysłowy, mieszkaniec dużego miasta</li> <li>Choroby współistniejące:</li> <ul> <li>Nadciśnienie tętnicze</li> <li>Choroba wieńcowa (leczony od 15 lat)</li> </ul> <li>Wieloletni palacz tytoniu, od 3 lat nie pali</li> <br> <br> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>19</font></div> </td> <td> <div id=3DPPTP19 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0027.htm');" id=3DPPTL19>Leczenie c.d.</= a></font></div> <div id=3DPPTC19 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Przy przyjęciu:</li> <li>Stan ogólny WHO I/II</li> <li>Nadciśnienie wyrównane lekami, zapis EKG bez cech ostrego niedokrwienia</li> <li>Układ krwiotwórczy, parametry wydolności wątro= by oraz poziom kreatyniny prawidłowe</li> <li>Poziom PSA narastający w ciągu 2 tyg<span style=3D'mso-spacerun:yes'> </span>z 79,8 do 168ng/ml</li> <li>Poziom testosteronu - kastracyjny</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>20</font></div> </td> <td> <div id=3DPPTP20 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0028.htm');" id=3DPPTL20>Chemioterapia</= a></font></div> <div id=3DPPTC20 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Docetaxel + Prednison w pełnych dawkach należnych</li> <li>Po I cyklu znaczące zmniejszenie dolegliwości bólow= ych (odstawiono opioidy)</li> <li>Łącznie IX cykli, bez opóźnień, bez toksyczności >WHO II, z dobra tolerancją</li> <li>Powolny spadek poziomu PSA do VI cyklu, następnie stabilizacja, (bez<span style=3D'mso-spacerun:yes'> </span>normalizacji)</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>21</font></div> </td> <td> <div id=3DPPTP21 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0029.htm');" id=3DPPTL21>Follow-up</a></= font></div> <div id=3DPPTC21 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Wobec braku dalszej regresji poziomu PSA, całkowitego ustąpienia dolegliwości bólowych oraz zmęczenia pacjenta chemioterapią odstąpiono od kontynuacji CHT i podjęto próbę leczenia hormonalnego (analog GN-RH + Bicalutamid) oraz bisfosfoniany.</li> <li>Leczenie prowadzono przez 9 miesięcy; stabily obraz kliniczny, poziom PSA ok. 20 ng/ml</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>22</font></div> </td> <td> <div id=3DPPTP22 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0030.htm');" id=3DPPTL22>Follow-up</a></= font></div> <div id=3DPPTC22 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Po 9 miesiącach progresja: nasilenie dolegliwości bólowych, narastanie PSA</li> <li>Naciek w trzonach kręgów L4 i L5 – stabilizacja operacyjna, a następnie paliatywna RT</li> <li>Wobec narastania objawów chorobowych<span style=3D'mso-spacerun:yes'> </span>w tym dolegliwości bólowych zdecydowano o ponownym włączeniu leczenia cytostatycznego</li> <li>Poziom PSA 210ng/ml</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>23</font></div> </td> <td> <div id=3DPPTP23 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0031.htm');" id=3DPPTL23>CHT – II = rzut</a></font></div> <div id=3DPPTC23 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Podano 2 cykle CHT w dawkach zredukowanych o 10%</li> <li>Uzyskano zmniejszenie dolegliwości<span style=3D'mso-spacerun:yes'> </span>bólowych, obniż= enie poziomu PSA do 62ng/ml</li> <li>Tolerancja leczenia dobra, bez toksyczności >WHO II</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>24</font></div> </td> <td> <div id=3DPPTP24 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0032.htm');" id=3DPPTL24>"W trakcie= pobytu w domu..."</a></font></div> <div id=3DPPTC24 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>W trakcie pobytu w domu ok. 10 dnia po CHT zawał mięś= nia sercowego zakończony zgonem (pacjent z wieloletnim wywiadem cho= roby wieńcowej i nadciśnienia) – zdarzenia nie wiążemy z CHT</li> <br> <br> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>25</font></div> </td> <td> <div id=3DPPTP25 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0045.htm');" id=3DPPTL25>Poziomy PSA w k= olejnych badaniach od początku CHT <br> Oznaczenia co 3-4 tyg</a></font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>26</font></div> </td> <td> <div id=3DPPTP26 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0033.htm');" id=3DPPTL26>Pacjent II</a><= /font></div> <div id=3DPPTC26 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>72 letni pracownik fizyczny, mieszkaniec małego miasta w woj. śląskim</li> <li>Przez 50 lat palił ok. 20 papierosów dziennie, od 5 lat = nie pali</li> <li>Bez istotnych klinicznie chorób współistniejących</li> <li>Rozpoznanie raka prostaty ustalono w stadium rozsiewu<span style=3D'mso-spacerun:yes'> </span>do kości w 70 roku życia</li> <li>Histologiczny stopień Gleason 8</li> <br> <br> <br> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>27</font></div> </td> <td> <div id=3DPPTP27 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0034.htm');" id=3DPPTL27>Wywiad Pacjent = II</a></font></div> <div id=3DPPTC27 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Leczony : pełna blokada hormonalna (Analog GN-RH + Bicalutamid) przez okres 22 miesięcy</li> <li>Przy pojawieniu się bólów kostnych i narastaniu poziomu PSA hormonoterapia II rzutu – nieskuteczna</li> <li>Z cechami hormonooporności (poziom PSA<span style=3D'mso-spacerun:yes'> </span>211ng/ml, poziom testostero= nu kastracyjny) oraz progresją kliniczną zakwalifikowany do C= HT</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>28</font></div> </td> <td> <div id=3DPPTP28 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0035.htm');" id=3DPPTL28>Pacjent II:<span style=3D'mso-spacerun:yes'> </span>CHT</a></font></div> <div id=3DPPTC28 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Otrzymał łącznie 8 cykli Docetaxel + Prednison.</li> <li>Tolerancja leczenia dobra. Ostatnie II cykle opóźnione o tydzień z powodu leukopenii</li> <li>Stopniowy spadek PSA do<span style=3D'mso-spacerun:yes'> </span>wartości rzędu 20ng/ml po 6 cyklu, następnie stabilizacja</li> <li>Całkowite ustąpienie dolegliwości bólowych</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>29</font></div> </td> <td> <div id=3DPPTP29 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0036.htm');" id=3DPPTL29>Pacjent II</a><= /font></div> <div id=3DPPTC29 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Po 8 cyklach wobec braku „spadku PSA” oraz dobrego samopoczucia pacjent odmówił kontynuacji leczenia</li> <li>Nie wyraził zgody na hormonoterapię</li> <li>Nie zgłaszał się do kontroli</li> <li>Po 9 miesiącach z nasilonymi bólami kostnymi oraz PSA> 1000 zgłosił się do kontroli.</li> <li>W badaniach obrazowych – progresja zmian osteosklerotycznych</= li> <br> <br> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>30</font></div> </td> <td> <div id=3DPPTP30 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0037.htm');" id=3DPPTL30>Pacjent II</a><= /font></div> <div id=3DPPTC30 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Włączono ponownie chemioterapię: Docetaxel (dawka zredukowana o 15% - uprzednie leukopenie) wraz z Prednisonem.</li> <li>Do chwili obecnej otrzymał 3 cykle</li> <li>Spadek poziomu PSA z >1000 do 786 i 470 ng/ml</li> <li>Tolerancja leczenia dobra.</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>31</font></div> </td> <td> <div id=3DPPTP31 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0046.htm');" id=3DPPTL31>Pacjent II<br> Poziomy PSA w trakcie CHT<br> Oznaczenia co 3-4<span style=3D'mso-spacerun:yes'> </span>tyg</a>= </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>32</font></div> </td> <td> <div id=3DPPTP32 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0024.htm');" id=3DPPTL32>Podsumowanie</a= ></font></div> <div id=3DPPTC32 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <br> <br> <li>Większość pacjentów<span style=3D'mso-spacerun:yes'> </span>z HRCP to starsi mężczyźni z typowymi dla tego wieku współistniejącymi<span style=3D'mso-spacerun:yes'>&= nbsp; </span>schorzeniami głównie układu krążen= ia</li> <br> <br> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>33</font></div> </td> <td> <div id=3DPPTP33 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0056.htm');" id=3DPPTL33>Podsumowanie<br> Docetaxel w HRPC</a></font></div> <div id=3DPPTC33 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Dobra tolerancja leczenia pomimo wieku pacjentów</li> <li>Terapia ze stosunkowo niewielką ilością istotnych klinicznie działań ubocznych</li> <li>Zysk kliniczny u znacznego odsetka leczonych zarówno w czasie= do progresji jak i jakości życia.</li> <li>Możliwość ponownej CHT - korzystna opcja w terapii HR= PC</li> <br> <br> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>34</font></div> </td> <td> <div id=3DPPTP34 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0051.htm');" id=3DPPTL34>ASCO 2009</a></= font></div> <div id=3DPPTC34 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li><span style=3D'mso-spacerun:yes'> </span>Standarde= m w leczeniu HRPC pozostaje docetaxel + Prednison</li> <br> <br> <li>Próby kojarzenia docetaxelu z innymi substancjami</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>35</font></div> </td> <td> <div id=3DPPTP35 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0057.htm');" id=3DPPTL35>Rak prostaty <b= r> Nowe aspekty ASCO 2009</a></font></div> <div id=3DPPTC35 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Wewnątrzguzowa synteza androgenów</li> <li>Wzmożenie wrażliwości (upregulation) receptora androgenowego w przerzutowym raku prostaty</li> <li><span style=3D'mso-spacerun:yes'> </span>Powyższe wyniki uzasadniają dwa bieżące trendy rozwoju leków dla przerzutowego raka gruczołu krokowego znajdujące się w fazie badań klinicznych</l= i> <li>Nowy antyandrogen MDV3100</li> <li>Inhibitor CYP17 -abirateron</li> <br> <br> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>36</font></div> </td> <td> <div id=3DPPTP36 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0052.htm');" id=3DPPTL36>Nowe terapie AS= CO 2009</a></font></div> <div id=3DPPTC36 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Receptor androgenowy pozostaje istotnym celem terapeutycznym nawet w HRPC</li> <li>MDV3100 jest obiecującym antyandrogenem o mechaniźmie działania odmiennym niż bicalutamid, aktywnym w HRPC zarówno przed jak i po chemioetrapii</li> <li>Preparat w trakcie badań klinicznych</li> </ul> </font></div> </td> </tr> <tr onmouseover=3D"Over(this)" onmouseout=3D"Out(this)" onclick=3D"Follow(= this)" style=3D'cursor:hand'> <td align=3Dright valign=3Dtop> <div class=3DsldNum><font size=3D2>37</font></div> </td> <td> <div id=3DPPTP37 class=3DPTxt><font size=3D2><a href=3D"javascript:GoToSld('slide0053.htm');" id=3DPPTL37>Nowe terapie AS= CO 2009<br> immunoterapia</a></font></div> <div id=3DPPTC37 class=3DCTxt style=3D'display:none'><font size=3D2> <ul> <li>Immunoterapia w leczeniu HRPC nie wykazała wpływu na ból, poziomy PSA lub chorobę mierzalną</li> <li>TYM NIEMNIEJ – nieoczekiwanie wykazano poprawę przeżyć całkowitych w 3 badaniach III fazy:</li> <ul> <li><span style=3D'mso-spacerun:yes'> </span>Sipuleucel-T</li> <li>sugerowana jest także przy użyciu PROSTVAC-VF-Tricom</li> </ul> <li>„BYĆ MOŻE IMMUNOTERAPIA DZIAŁA”</li> <li>(komentarz prowadzącego sesję)</li> </ul> </font></div> </td> </tr> </table> </div> <div style=3D'display:none'><a href=3D"../OptymalnyprofilchoregozHRCP.htm">= 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